Publications by authors named "Jacques Ghysdael"

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Targeting the TNF/IAP pathway synergizes with anti-CD3 immunotherapy in T-cell acute lymphoblastic leukemia.
Andrea Ávila Ávila, Kanokporn Nuantang, Mariana L Oliveira, Sabine Druillennec, Benedetta Zaniboni, Jacques Ghysdael

Blood· May 2024

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Harnessing the MYB-dependent TAL1 5'super-enhancer for targeted therapy in T-ALL.
Charlotte Smith, Aurore Touzart, Mathieu Simonin, Christine Tran-Quang, Guillaume Hypolite, Jacques Ghysdael

Mol Cancer· January 2023

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Preclinical Evaluation of a Novel Small Molecule Inhibitor of LIM Kinases (LIMK) CEL_Amide in Philadelphia-Chromosome Positive () Acute Lymphoblastic Leukemia (ALL).
Jeannig Berrou, Mélanie Dupont, Hanane Djamai, Emilie Adicéam, Véronique Parietti, Jacques Ghysdael

J Clin Med· November 2022

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AXL Inhibition in Macrophages Stimulates Host-versus-Leukemia Immunity and Eradicates Naïve and Treatment-Resistant Leukemia.
Irene Tirado-Gonzalez, Arnaud Descot, Devona Soetopo, Aleksandra Nevmerzhitskaya, Alexander Schäffer, Jacques Ghysdael

Cancer Discov· November 2021

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NFAT transcription factors are essential and redundant actors for leukemia initiating potential in T-cell acute lymphoblastic leukemia.
Claire Catherinet, Diana Passaro, Stéphanie Gachet, Hind Medyouf, Anne Reynaud, Jacques Ghysdael

PLoS One· November 2021

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Epigenetic analysis of patients with T-ALL identifies poor outcomes and a hypomethylating agent-responsive subgroup.
Aurore Touzart, Anand Mayakonda, Charlotte Smith, Joschka Hey, Reka Toth, Jacques Ghysdael

Sci Transl Med· May 2021

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Preclinical efficacy of humanized, non-FcγR-binding anti-CD3 antibodies in T-cell acute lymphoblastic leukemia.
Christine Tran Quang, Benedetta Zaniboni, Romain Humeau, Etienne Lengliné, Marie Emilie Dourthe, Jacques Ghysdael

Blood· September 2020

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The TCR/CD3 complex in leukemogenesis and as a therapeutic target in T-cell acute lymphoblastic leukemia.
Nuno R Dos Santos, Jacques Ghysdael, Christine Tran Quang

Adv Biol Regul· December 2019

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Novel Intergenically Spliced Chimera, , Is Associated with Aggressive T-ALL Biology and Outcome.
Jonathan Bond, Christine Tran Quang, Guillaume Hypolite, Mohamed Belhocine, Aurélie Bergon, Jacques Ghysdael

Mol Cancer Res· March 2018

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A TCR-switchable cell death pathway in T-ALL.
Christine Tran Quang, Benedetta Zaniboni, Jacques Ghysdael

Oncoscience· March 2017

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Triggering the TCR Developmental Checkpoint Activates a Therapeutically Targetable Tumor Suppressive Pathway in T-cell Leukemia.
Amélie Trinquand, Nuno R Dos Santos, Christine Tran Quang, Francesca Rocchetti, Benedetta Zaniboni, Jacques Ghysdael

Cancer Discov· September 2016

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Microenvironmental cues for T-cell acute lymphoblastic leukemia development.
Diana Passaro, Christine Tran Quang, Jacques Ghysdael

Immunol Rev· May 2016

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Lymphotoxin-β receptor in microenvironmental cells promotes the development of T-cell acute lymphoblastic leukaemia with cortical/mature immunophenotype.
Mónica T Fernandes, Marinella N Ghezzo, André B Silveira, Ravi K Kalathur, Vanda Póvoa, Jacques Ghysdael

Br J Haematol· December 2015

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Calcineurin/CXCR4 in T-ALL.
Diana Passaro, Christine Tran Quang, Jacques Ghysdael

Oncoscience· December 2015

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Control of CD8 T cell proliferation and terminal differentiation by active STAT5 and CDKN2A/CDKN2B.
Magali Grange, Marilyn Giordano, Amandine Mas, Romain Roncagalli, Guylène Firaguay, Jacques Ghysdael

Immunology· August 2015

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CXCR4 Is Required for Leukemia-Initiating Cell Activity in T Cell Acute Lymphoblastic Leukemia.
Diana Passaro, Marta Irigoyen, Claire Catherinet, Stéphanie Gachet, Cindy Da Costa De Jesus, Jacques Ghysdael

Cancer Cell· June 2015

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Lethal giant larvae 1 tumour suppressor activity is not conserved in models of mammalian T and B cell leukaemia.
Edwin D Hawkins, Jane Oliaro, Kelly M Ramsbottom, Stephen B Ting, Faruk Sacirbegovic, Jacques Ghysdael

PLoS One· September 2014

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Interleukin-18 produced by bone marrow-derived stromal cells supports T-cell acute leukaemia progression.
Benjamin Uzan, Sandrine Poglio, Bastien Gerby, Ching-Lien Wu, Julia Gross, Jacques Ghysdael

EMBO Mol Med· June 2014

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Deregulation of AhR function by the human acute leukemia TEL-ARNT fusion protein.
Florence Nguyen-Khac, Véronique Della Valle, Rodolphe G Lopez, Jacques Ghysdael, Olivier A Bernard

Am J Hematol· May 2014

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Combined targeting of JAK2 and Bcl-2/Bcl-xL to cure mutant JAK2-driven malignancies and overcome acquired resistance to JAK2 inhibitors.
Michaela Waibel, Vanessa S Solomon, Deborah A Knight, Rachael A Ralli, Sang-Kyu Kim, Jacques Ghysdael

Cell Rep· November 2013

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ISG15 modulates development of the erythroid lineage.
Ana Leticia Maragno, Martine Pironin, Hélène Alcalde, Xiuli Cong, Klaus-Peter Knobeloch, Jacques Ghysdael

PLoS One· February 2012

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Oncogenic activation of the Notch1 gene by deletion of its promoter in Ikaros-deficient T-ALL.
Robin Jeannet, Jérôme Mastio, Alejandra Macias-Garcia, Attila Oravecz, Todd Ashworth, Jacques Ghysdael

Blood· December 2010

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Calcineurin/NFAT signaling in lymphoid malignancies.
Stephanie Gachet, Jacques Ghysdael

Gen Physiol Biophys· August 2010

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RAG-1 and ATM coordinate monoallelic recombination and nuclear positioning of immunoglobulin loci.
Susannah L Hewitt, Bu Yin, Yanhong Ji, Julie Chaumeil, Katarzyna Marszalek, Jacques Ghysdael

Nat Immunol· June 2009

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RelB-dependent stromal cells promote T-cell leukemogenesis.
Nuno R dos Santos, Maryvonne Williame, Stéphanie Gachet, Françoise Cormier, Anne Janin, Jacques Ghysdael

PLoS One· July 2008

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