Publications by authors named "James Bischoff"

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Evaluation of STK17B as a cancer immunotherapy target utilizing highly potent and selective small molecule inhibitors.
Felix Scheuplein, Florian Renner, John E Campbell, Robert Campbell, Chris De Savi, James R Bischoff

Front Immunol· November 2024

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Discovery of Novel Allosteric EGFR L858R Inhibitors for the Treatment of Non-Small-Cell Lung Cancer as a Single Agent or in Combination with Osimertinib.
Ulrike Obst-Sander, Antonio Ricci, Bernd Kuhn, Thomas Friess, Philipp Koldewey, James R Bischoff

J Med Chem· October 2022

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DUSP4 protects BRAF- and NRAS-mutant melanoma from oncogene overdose through modulation of MITF.
Nuria Gutierrez-Prat, Hedwig L Zuberer, Luca Mangano, Zahra Karimaddini, Luise Wolf, James R Bischoff

Life Sci Alliance· September 2022

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Activity and Resistance of a Brain-Permeable Paradox Breaker BRAF Inhibitor in Melanoma Brain Metastasis.
Ester Bonfill-Teixidor, Raffaella Iurlaro, Cornelia Handl, Jürgen Wichmann, Alexandra Arias, James R Bischoff

Cancer Res· July 2022

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Preclinical Characterization of a Next-Generation Brain Permeable, Paradox Breaker BRAF Inhibitor.
Jürgen Wichmann, Caroline Rynn, Thomas Friess, Jeannine Petrig-Schaffland, Martin Kornacker, James R Bischoff

Clin Cancer Res· February 2022

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2021 ACC/AHA/SCAI Guideline for Coronary Artery Revascularization: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines.
Jennifer S Lawton, Jacqueline E Tamis-Holland, Sripal Bangalore, Eric R Bates, Theresa M Beckie, James M Bischoff

Circulation· January 2022

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2021 ACC/AHA/SCAI Guideline for Coronary Artery Revascularization: Executive Summary: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines.
Jennifer S Lawton, Jacqueline E Tamis-Holland, Sripal Bangalore, Eric R Bates, Theresa M Beckie, James M Bischoff

Circulation· January 2022

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2021 ACC/AHA/SCAI Guideline for Coronary Artery Revascularization: Executive Summary: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines.

J Am Coll Cardiol· January 2022

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Lay Stakeholders in Science and Research Initiative: A Science Advisory From the American Heart Association.
William H Roach, James M Bischoff, Bernie Dennis, Marvis Donalson, Sandra B Dunbar

Circulation· August 2021

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Spirocyclic Thiohydantoin Antagonists of F877L and Wild-Type Androgen Receptor for Castration-Resistant Prostate Cancer.
Zhuming Zhang, Peter J Connolly, Luis Trabalón Escolar, Christian Rocaboy, Vineet Pande, James R Bischoff

ACS Med Chem Lett· August 2021

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Discovery of JNJ-63576253, a Next-Generation Androgen Receptor Antagonist Active Against Wild-Type and Clinically Relevant Ligand Binding Domain Mutations in Metastatic Castration-Resistant Prostate Cancer.
Jonathan R Branch, Tammy L Bush, Vineet Pande, Peter J Connolly, Zhuming Zhang, James R Bischoff

Mol Cancer Ther· May 2021

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Discovery of JNJ-63576253: A Clinical Stage Androgen Receptor Antagonist for F877L Mutant and Wild-Type Castration-Resistant Prostate Cancer (mCRPC).
Zhuming Zhang, Peter J Connolly, Heng Keang Lim, Vineet Pande, Lieven Meerpoel, James R Bischoff

J Med Chem· January 2021

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Cellular Resistance Mechanisms to Targeted Protein Degradation Converge Toward Impairment of the Engaged Ubiquitin Transfer Pathway.
Philipp Ottis, Chiara Palladino, Phillip Thienger, Adrian Britschgi, Christian Heichinger, James R Bischoff

ACS Chem Biol· October 2019

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Discovery of novel triazolo[4,3-b]pyridazin-3-yl-quinoline derivatives as PIM inhibitors.
Sonia Martínez-González, Sonsoles Rodríguez-Arístegui, Cristina Ana Gómez de la Oliva, Ana Isabel Hernández, Esther González Cantalapiedra, James R Bischoff

Eur J Med Chem· April 2019

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Ketamine as an Analgesic Adjuvant in Adult Trauma Intensive Care Unit Patients With Rib Fracture.
Mary K Walters, Joseph Farhat, James Bischoff, Mary Foss, Cory Evans

Ann Pharmacother· September 2018

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Design and synthesis of a series of bioavailable fatty acid synthase (FASN) KR domain inhibitors for cancer therapy.
Tianbao Lu, Carsten Schubert, Maxwell D Cummings, Gilles Bignan, Peter J Connolly, James Bischoff

Bioorg Med Chem Lett· July 2018

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Identification of novel PI3K inhibitors through a scaffold hopping strategy.
Sonia Martínez González, Ana Isabel Hernández, Rosa María Álvarez, Antonio Rodríguez, Francisco Ramos-Lima, James R Bischoff

Bioorg Med Chem Lett· November 2017

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Generation of tricyclic imidazo[1,2-a]pyrazines as novel PI3K inhibitors by application of a conformational restriction strategy.
Sonia Martínez González, Sonsoles Rodríguez-Arístegui, Ana Isabel Hernández, Carmen Varela, Esther González Cantalapiedra, James R Bischoff

Bioorg Med Chem Lett· June 2017

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PIM kinases as potential therapeutic targets in a subset of peripheral T cell lymphoma cases.
Esperanza Martín-Sánchez, Lina Odqvist, Socorro M Rodríguez-Pinilla, Margarita Sánchez-Beato, Giovanna Roncador, James R Bischoff

PLoS One· December 2015

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Bayesian chronological analyses consistent with synchronous age of 12,835-12,735 Cal B.P. for Younger Dryas boundary on four continents.
James P Kennett, Douglas J Kennett, Brendan J Culleton, J Emili Aura Tortosa, James L Bischoff

Proc Natl Acad Sci U S A· August 2015

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Combined ESR/U-series chronology of Acheulian hominid-bearing layers at Trinchera Galería site, Atapuerca, Spain.
Christophe Falguères, Jean-Jacques Bahain, James L Bischoff, Alfredo Pérez-González, Ana Isabel Ortega

J Hum Evol· August 2013

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Evidence for deposition of 10 million tonnes of impact spherules across four continents 12,800 y ago.
James H Wittke, James C Weaver, Ted E Bunch, James P Kennett, Douglas J Kennett, James L Bischoff

Proc Natl Acad Sci U S A· June 2013

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Fragment-hopping-based discovery of a novel chemical series of proto-oncogene PIM-1 kinase inhibitors.
Gustavo Saluste, Maria I Albarran, Rosa M Alvarez, Obdulia Rabal, Miguel Angel Ortega, James R Bischoff

PLoS One· April 2013

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