Publications by authors named "James Costello"

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A Roadmap for the Future of Systems Biology in Cancer Research.
H Steven Wiley, Carlos F Lopez, Andrei S Rodin, Russell C Rockne, Thomas E Yankeelov, James C Costello

Cancer Res· December 2025

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Microbiome preterm birth DREAM challenge: Crowdsourcing machine learning approaches to advance preterm birth research.
Jonathan L Golob, Tomiko T Oskotsky, Alice S Tang, Alennie Roldan, Verena Chung, James C Costello

Cell Rep Med· December 2025

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eIF3d and eIF3e mediate selective translational control of hypoxia that can be inhibited by small molecules.
Stephen C Purdy, Kate Matlin, Christopher Alderman, Amber Baldwin, Natasha Shrivastava, James C Costello

Cell Rep· December 2025

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Magnetoelectric Nanotherapy Achieves Complete Tumor Ablation and Prolonged Survival in Pancreatic Cancer Murine Models.
John Michael Bryant, Max Shotbolt, Emmanuel Stimphil, Victoria Andre, Elric Zhang, James Costello

Adv Sci (Weinh)· November 2025

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A phase II, randomized, double-blind study of the use of rucaparib vs. placebo maintenance therapy in metastatic and recurrent endometrial cancer.
Bradley R Corr, Ashley Haggerty, Stefan M Gysler, Sarah Taylor, Kian Behbakht, James Costello

Gynecol Oncol· September 2025

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Respiratory viral infections awaken metastatic breast cancer cells in lungs.
Shi B Chia, Bryan J Johnson, Junxiao Hu, Felipe Valença-Pereira, Marc Chadeau-Hyam, James C Costello

Nature· September 2025

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Standardized reporting of extrahepatic cholangiocarcinoma.
Maria El Homsi, Omar T Hassan, Ciara O'Brien, Charanjeet Singh, Hina Arif-Tiwari, James Costello

Abdom Radiol (NY)· September 2025

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Systems biology successes and areas for opportunity in prostate cancer.
Michael V Orman, Laura S Graham, Scott D Cramer, James C Costello

Endocr Relat Cancer· August 2025

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GRACKLE: an interpretable matrix factorization approach for biomedical representation learning.
Lucas A Gillenwater, Lawrence E Hunter, James C Costello

Bioinformatics· July 2025

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Molecular signatures of intrahepatic cholangiocarcinoma: role in targeted therapy selection.
Tetiana Glushko, James Costello, Ranjit Chima, Melissa McGettigan, Richard Kim

Eur J Radiol· June 2025

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EYA3 regulation of NF-κB and CCL2 suppresses cytotoxic NK cells in the premetastatic niche to promote TNBC metastasis.
Sheera R Rosenbaum, Connor J Hughes, Kaiah M Fields, Stephen Connor Purdy, Annika L Gustafson, James C Costello

Sci Adv· May 2025

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Whole-body MRI for a patient with progressive multiple myeloma.
Jonathan E Henning, Taiga Nishihori, Ciara Freeman, Alexander Lazarides, Jinming Song, James R Costello

BJR Case Rep· May 2025

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eIF3d and eIF3e mediate selective translational control of hypoxia that can be inhibited by novel small molecules.
Stephen C Purdy, Kate Matlin, Christopher Alderman, Amber Baldwin, Natasha Shrivastava, James C Costello

bioRxiv· May 2025

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Adenine base editing with engineered virus-like particles rescues the mutation G542X in patient-derived intestinal organoids.
Lucia Nicosia, Iwona Pranke, Roberta V Latorre, Joss B Murray, Lisa Lonetti, James P Costello

iScience· March 2025

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Editorial: State-of-the-art hypothesis-driven systems pharmacology and artificial intelligence approaches to decipher disease complexity.
Cristina Correia, Choong-Yong Ung, Hu Li, James C Costello

Front Pharmacol· March 2025

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Imaging cholangiocarcinoma: CT and MRI techniques.
Andrea S Kierans, James Costello, Aliya Qayyum, Bachir Taouli, Sudhakar K Venkatesh

Abdom Radiol (NY)· January 2025

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A Pathway-Level Information ExtractoR (PLIER) framework to gain mechanistic insights into obesity in Down syndrome.
Sutanu Nandi, Yuehua Zhu, Lucas A Gillenwater, Marc Subirana-Granés, Haoyu Zhang, James C Costello

Pac Symp Biocomput· December 2024

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Regulation of volume-regulated anion channels alters sensitivity to platinum chemotherapy.
Lily Elizabeth R Feldman, Saswat Mohapatra, Robert T Jones, Mathijs Scholtes, Charlene B Tilton, James C Costello

Sci Adv· December 2024

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Integrated analysis of immunometabolic interactions in Down syndrome.
Lucas A Gillenwater, Matthew D Galbraith, Angela L Rachubinski, Neetha Paul Eduthan, Kelly D Sullivan, James C Costello

Sci Adv· December 2024

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Nanoparticles use magnetoelectricity to target and eradicate cancer cells.
John Michael Bryant, Emmanuel Stimphil, Victoria Andre, Max Shotbolt, Elric Zhang, James Costello

bioRxiv· October 2024

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Management of bone disease with concurrent chimeric antigen receptor T-cell therapy for multiple myeloma.
Davis Kuruvilla, Thien Huynh, Matthew Nester, Chloe Chose, Guston Zervoudakis, James R Costello

Crit Rev Oncol Hematol· September 2024

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An EYA3/NF-κB/CCL2 signaling axis suppresses cytotoxic NK cells in the pre-metastatic niche to promote triple negative breast cancer metastasis.
Sheera R Rosenbaum, Connor J Hughes, Kaiah M Fields, Stephen Connor Purdy, Annika Gustafson, James C Costello

bioRxiv· August 2024

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E-cadherin expression and gene expression profiles in corticotroph pituitary neuroendocrine tumor subtypes.
Katja Kiseljak-Vassiliades, Kristin Lipe, Christie G Turin, Lauren Fishbein, James C Costello

J Neuropathol Exp Neurol· June 2024

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ProstaMine: a bioinformatics tool for identifying subtype-specific co-alterations associated with aggressiveness in prostate cancer.
Michael V Orman, Varsha Sreekanth, Teemu D Laajala, Scott D Cramer, James C Costello

Front Pharmacol· May 2024

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Magnetic resonance imaging of tumor response to stroma-modifying pegvorhyaluronidase alpha (PEGPH20) therapy in early-phase clinical trials.
Andrés M Arias-Lorza, James R Costello, Sunil R Hingorani, Daniel D Von Hoff, Ronald L Korn

Sci Rep· May 2024

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