Publications by authors named "James Jewell"

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The prevelance of psychosis in indigenous populations in Australia: A review of the literature using systematic methods.
James Jewell, David Mitchell

Australas Psychiatry· June 2023

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An orally available non-nucleotide STING agonist with antitumor activity.
Bo-Sheng Pan, Samanthi A Perera, Jennifer A Piesvaux, Jeremy P Presland, Gottfried K Schroeder, James Jewell

Science· August 2020

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Discovery of a Novel cGAMP Competitive Ligand of the Inactive Form of STING.
Tony Siu, Michael D Altman, Gretchen A Baltus, Matthew Childers, J Michael Ellis, James Jewell

ACS Med Chem Lett· January 2019

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Structure guided design of a series of selective pyrrolopyrimidinone MARK inhibitors.
Jason D Katz, Andrew Haidle, Kaleen K Childers, Anna A Zabierek, James P Jewell

Bioorg Med Chem Lett· January 2017

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MARK inhibitors: Declaring a No-Go decision on a chemical series based on extensive DMPK experimentation.
Andrew M Haidle, Kaleen K Childers, Anna A Zabierek, Jason D Katz, James P Jewell

Bioorg Med Chem Lett· January 2017

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Reducing postoperative infections and red breast syndrome in patients with acellular dermal matrix-based breast reconstruction: the relative roles of product sterility and lower body mass index.
Priya Lewis, James Jewell, Gennaya Mattison, Subhas Gupta, Hahns Kim

Ann Plast Surg· May 2015

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Overcoming mutagenicity and ion channel activity: optimization of selective spleen tyrosine kinase inhibitors.
J Michael Ellis, Michael D Altman, Alan Bass, John W Butcher, Alan J Byford, James Jewell

J Med Chem· February 2015

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The impact of operative time on complications after plastic surgery: a multivariate regression analysis of 1753 cases.
Krista L Hardy, Kathryn E Davis, Ryan S Constantine, Mo Chen, Rachel Hein, James L Jewell

Aesthet Surg J· May 2014

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Impact of pen utilization on insulin cost reduction in long-term care facilities.
Gary Bazalo, Richard C Weiss, Jonathan R Bouchard, Ronald G Perry, Frederick L Wendt, James L Jewell

Consult Pharm· June 2012

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Discovery of a 5H-benzo[4,5]cyclohepta[1,2-b]pyridin-5-one (MK-2461) inhibitor of c-Met kinase for the treatment of cancer.
Jason D Katz, James P Jewell, David J Guerin, Jongwon Lim, Christopher J Dinsmore

J Med Chem· June 2011

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Discovery of MK-5046, a Potent, Selective Bombesin Receptor Subtype-3 Agonist for the Treatment of Obesity.
Iyassu K Sebhat, Christopher Franklin, Michael M-C Lo, David Chen, James P Jewell

ACS Med Chem Lett· January 2011

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Synthesis and cannabinoid-1 receptor binding affinity of conformationally constrained analogs of taranabant.
Ihor E Kopka, Linus S Lin, James P Jewell, Thomas J Lanza, Tung M Fong

Bioorg Med Chem Lett· August 2010

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MK-2461, a novel multitargeted kinase inhibitor, preferentially inhibits the activated c-Met receptor.
Bo-Sheng Pan, Grace K Y Chan, Melissa Chenard, An Chi, Lenora J Davis, James P Jewell

Cancer Res· February 2010

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A comparison of outcomes involving highly cohesive, form-stable breast implants from two manufacturers in patients undergoing primary breast augmentation.
Mark L Jewell, James L Jewell

Aesthet Surg J· January 2010

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PET imaging studies in rhesus monkey with the cannabinoid-1 (CB1) receptor ligand [11C]CB-119.
Terence G Hamill, Linus S Lin, William Hagmann, Ping Liu, James Jewell

Mol Imaging Biol· October 2009

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Synthesis and evaluation of N-[(1S,2S)-3-(4-chlorophenyl)-2-(3-cyanophenyl)-1-methylpropyl]-2-methyl-2-aminopropanamide as human cannabinoid-1 receptor (CB1R) inverse agonists.
Wu Du, James P Jewell, Linus S Lin, Vincent J Colandrea, Jing C Xiao

Bioorg Med Chem Lett· September 2009

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Discovery of N-{N-[(3-cyanophenyl)sulfonyl]-4(R)-cyclobutylamino-(L)-prolyl}-4-[(3',5'-dichloroisonicotinoyl) amino]-(L)-phenylalanine (MK-0668), an extremely potent and orally active antagonist of very late antigen-4.
Linus S Lin, Thomas Lanza, James P Jewell, Ping Liu, Carrie Jones

J Med Chem· June 2009

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Similar in vitro pharmacology of human cannabinoid CB1 receptor variants expressed in CHO cells.
Jing Chen Xiao, James P Jewell, Linus S Lin, William K Hagmann, Tung M Fong

Brain Res· October 2008

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Discovery of N-{(1S,2S)-2-(3-cyanophenyl)- 3-[4-(2-[18F]fluoroethoxy)phenyl]-1-methylpropyl}- 2-methyl-2-[(5-methylpyridin-2-yl)oxy]propanamide, a cannabinoid-1 receptor positron emission tomography tracer suitable for clinical use.
Ping Liu, Linus S Lin, Terence G Hamill, James P Jewell, Thomas J Lanza

J Med Chem· July 2007

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Antiobesity efficacy of a novel cannabinoid-1 receptor inverse agonist, N-[(1S,2S)-3-(4-chlorophenyl)-2-(3-cyanophenyl)-1-methylpropyl]-2-methyl-2-[[5-(trifluoromethyl)pyridin-2-yl]oxy]propanamide (MK-0364), in rodents.
Tung M Fong, Xiao-Ming Guan, Donald J Marsh, Chun-Pyn Shen, D Sloan Stribling, James P Jewell

J Pharmacol Exp Ther· June 2007

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[18F]MK-9470, a positron emission tomography (PET) tracer for in vivo human PET brain imaging of the cannabinoid-1 receptor.
H Donald Burns, Koen Van Laere, Sandra Sanabria-Bohórquez, Terence G Hamill, Guy Bormans, James P Jewell

Proc Natl Acad Sci U S A· June 2007

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Substituted acyclic sulfonamides as human cannabinoid-1 receptor inverse agonists.
Helen E Armstrong, Amy Galka, Linus S Lin, Thomas J Lanza, James P Jewell

Bioorg Med Chem Lett· April 2007

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Discovery of N-[(1S,2S)-3-(4-Chlorophenyl)-2- (3-cyanophenyl)-1-methylpropyl]-2-methyl-2- {[5-(trifluoromethyl)pyridin-2-yl]oxy}propanamide (MK-0364), a novel, acyclic cannabinoid-1 receptor inverse agonist for the treatment of obesity.
Linus S Lin, Thomas J Lanza, James P Jewell, Ping Liu, Shrenik K Shah

J Med Chem· December 2006

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Addressing the metabolic activation potential of new leads in drug discovery: a case study using ion trap mass spectrometry and tritium labeling techniques.
Koppara Samuel, Wenji Yin, Ralph A Stearns, Yui S Tang, Ashok G Chaudhary, James P Jewell

J Mass Spectrom· February 2003

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