Publications by authors named "James Sidaway"

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Data science in drug discovery safety: Challenges and opportunities.
Nicholas J Coltman, Ruth A Roberts, James E Sidaway

Exp Biol Med (Maywood)· November 2023

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Editorial: COVID-19 in the tropics.
James D Sidaway

Singap J Trop Geogr· May 2021

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Label-Free Quantitative Proteomics and Substrate-Based Mass Spectrometry Imaging of Xenobiotic Metabolizing Enzymes in Ex Vivo Human Skin and a Human Living Skin Equivalent Model.
Narciso Couto, Jillian R A Newton, Cristina Russo, Esther Karunakaran, Brahim Achour, James Sidaway

Drug Metab Dispos· January 2021

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Analysis of β-catenin gene mutations and gene expression in liver tumours of C57BL/10J mice produced by chronic administration of sodium phenobarbital.
James E Sidaway, Terry C Orton, Kassiani Kalaitzi, Huw B Jones, Alison Foster

Toxicology· January 2020

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Modeling of Bile Acid Processing by the Human Fecal Microbiota.
Glynn Martin, Sofia Kolida, Julian R Marchesi, Elizabeth Want, James E Sidaway

Front Microbiol· June 2018

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Innovative organotypic in vitro models for safety assessment: aligning with regulatory requirements and understanding models of the heart, skin, and liver as paradigms.
Chris S Pridgeon, Constanze Schlott, Min Wei Wong, Minne B Heringa, Tobias Heckel, James Sidaway

Arch Toxicol· February 2018

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Statin regulated ERK5 stimulates tight junction formation and reduces permeability in human cardiac endothelial cells.
Emma L Wilkinson, James E Sidaway, Michael J Cross

J Cell Physiol· January 2018

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Preclinical imaging methods for assessing the safety and efficacy of regenerative medicine therapies.
Lauren Scarfe, Nathalie Brillant, J Dinesh Kumar, Noura Ali, Ahmed Alrumayh, James Sidaway

NPJ Regen Med· October 2017

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Towards better models and mechanistic biomarkers for drug-induced gastrointestinal injury.
Daniel F Carr, Seyoum Ayehunie, Andrea Davies, Carrie A Duckworth, Stephanie French, James E Sidaway

Pharmacol Ther· April 2017

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Cardiotoxic drugs Herceptin and doxorubicin inhibit cardiac microvascular endothelial cell barrier formation resulting in increased drug permeability.
Emma L Wilkinson, James E Sidaway, Michael J Cross

Biol Open· October 2016

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Cardiac Non-myocyte Cells Show Enhanced Pharmacological Function Suggestive of Contractile Maturity in Stem Cell Derived Cardiomyocyte Microtissues.
Stephanie M Ravenscroft, Amy Pointon, Awel W Williams, Michael J Cross, James E Sidaway

Toxicol Sci· July 2016

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MicroRNA-122: a novel hepatocyte-enriched in vitro marker of drug-induced cellular toxicity.
Richard Kia, Lorna Kelly, Rowena L C Sison-Young, Fang Zhang, Chris S Pridgeon, James Sidaway

Toxicol Sci· March 2015

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Probiotic administration attenuates myocardial hypertrophy and heart failure after myocardial infarction in the rat.
Xiaohong Tracey Gan, Grace Ettinger, Cathy X Huang, Jeremy P Burton, James V Haist, James E Sidaway

Circ Heart Fail· May 2014

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Characterization of the adenosine pharmacology of ticagrelor reveals therapeutically relevant inhibition of equilibrative nucleoside transporter 1.
Duncan Armstrong, Claire Summers, Lorna Ewart, Sven Nylander, James E Sidaway

J Cardiovasc Pharmacol Ther· March 2014

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Safety pharmacology--current and emerging concepts.
Junnat Hamdam, Swaminathan Sethu, Trevor Smith, Ana Alfirevic, Mohammad Alhaidari, James Sidaway

Toxicol Appl Pharmacol· December 2013

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Phenotypic profiling of structural cardiotoxins in vitro reveals dependency on multiple mechanisms of toxicity.
Amy Pointon, Najah Abi-Gerges, Michael J Cross, James E Sidaway

Toxicol Sci· April 2013

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Pharmacological activation of the pyruvate dehydrogenase complex reduces statin-mediated upregulation of FOXO gene targets and protects against statin myopathy in rodents.
Joanne E Mallinson, Dumitru Constantin-Teodosiu, Philip D Glaves, Elizabeth A Martin, Wendy J Davies, James E Sidaway

J Physiol· December 2012

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Ticagrelor inhibits adenosine uptake in vitro and enhances adenosine-mediated hyperemia responses in a canine model.
J J J van Giezen, James Sidaway, Philip Glaves, Ian Kirk, Jan-Arne Björkman

J Cardiovasc Pharmacol Ther· June 2012

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Variation in antibiotic-induced microbial recolonization impacts on the host metabolic phenotypes of rats.
Jonathan R Swann, Kieran M Tuohy, Peter Lindfors, Duncan T Brown, Glenn R Gibson, James Sidaway

J Proteome Res· August 2011

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Systemic gut microbial modulation of bile acid metabolism in host tissue compartments.
Jonathan R Swann, Elizabeth J Want, Florian M Geier, Konstantina Spagou, Ian D Wilson, James E Sidaway

Proc Natl Acad Sci U S A· March 2011

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Gut microbiome modulates the toxicity of hydrazine: a metabonomic study.
Jonathan Swann, Yulan Wang, Leticia Abecia, Adele Costabile, Kieran Tuohy, James Sidaway

Mol Biosyst· April 2009

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Blunted Akt/FOXO signalling and activation of genes controlling atrophy and fuel use in statin myopathy.
Joanne E Mallinson, Dumitru Constantin-Teodosiu, James Sidaway, F Russell Westwood, Paul L Greenhaff

J Physiol· January 2009

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Statins but not thiazolidinediones attenuate albumin-mediated chemokine production by proximal tubular cells independently of endocytosis.
Ravinder S Chana, James E Sidaway, Nigel J Brunskill

Am J Nephrol· October 2008

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Systems toxicology: integrated genomic, proteomic and metabonomic analysis of methapyrilene induced hepatotoxicity in the rat.
Andrew Craig, James Sidaway, Elaine Holmes, Terry Orton, David Jackson

J Proteome Res· July 2006

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Inhibitors of 3-hydroxy-3-methylglutaryl-CoA reductase reduce receptor-mediated endocytosis in opossum kidney cells.
James E Sidaway, Robert G Davidson, Fergus McTaggart, Terry C Orton, Robert C Scott

J Am Soc Nephrol· September 2004

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