Publications by authors named "Jan Boitz"

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Proteomic Profiling of Leishmania donovani Promastigote Subcellular Organelles.
Armando Jardim, Darryl B Hardie, Jan Boitz, Christoph H Borchers

J Proteome Res· March 2018

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Arginase Is Essential for Survival of Leishmania donovani Promastigotes but Not Intracellular Amastigotes.
Jan M Boitz, Caslin A Gilroy, Tamara D Olenyik, Dustin Paradis, Jasmine Perdeh

Infect Immun· January 2017

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Targeting the Cytochrome bc1 Complex of Leishmania Parasites for Discovery of Novel Drugs.
Diana Ortiz, Isaac Forquer, Jan Boitz, Radika Soysa, Carolyn Elya

Antimicrob Agents Chemother· August 2016

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GMP reductase and genetic uncoupling of adenylate and guanylate metabolism in Leishmania donovani parasites.
Jan M Boitz, Armando Jardim, Buddy Ullman

Mol Biochem Parasitol· August 2016

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A role for adenine nucleotides in the sensing mechanism to purine starvation in Leishmania donovani.
Jessica L Martin, Phillip A Yates, Jan M Boitz, Dennis R Koop, Audrey L Fulwiler

Mol Microbiol· July 2016

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The cystathionine-β-synthase domains on the guanosine 5''-monophosphate reductase and inosine 5'-monophosphate dehydrogenase enzymes from Leishmania regulate enzymatic activity in response to guanylate and adenylate nucleotide levels.
Sabrina Smith, Jan Boitz, Ehzilan Subramanian Chidambaram, Abhishek Chatterjee, Maria Ait-Tihyaty

Mol Microbiol· June 2016

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Adenine and adenosine salvage in Leishmania donovani.
Jan M Boitz, Buddy Ullman

Mol Biochem Parasitol· August 2013

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Adenylosuccinate synthetase and adenylosuccinate lyase deficiencies trigger growth and infectivity deficits in Leishmania donovani.
Jan M Boitz, Rona Strasser, Phillip A Yates, Armando Jardim, Buddy Ullman

J Biol Chem· March 2013

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Purine salvage in Leishmania: complex or simple by design?
Jan M Boitz, Buddy Ullman, Armando Jardim, Nicola S Carter

Trends Parasitol· August 2012

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Genetic dissection of pyrimidine biosynthesis and salvage in Leishmania donovani.
Zachary N Wilson, Caslin A Gilroy, Jan M Boitz, Buddy Ullman, Phillip A Yates

J Biol Chem· April 2012

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Adenine aminohydrolase from Leishmania donovani: unique enzyme in parasite purine metabolism.
Jan M Boitz, Rona Strasser, Charles U Hartman, Armando Jardim, Buddy Ullman

J Biol Chem· March 2012

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IMP dehydrogenase deficiency in Leishmania donovani causes a restrictive growth phenotype in promastigotes but is not essential for infection in mice.
Audrey L Fulwiler, Jan M Boitz, Caslin Gilroy, Phillip A Yates, Armando Jardim

Mol Biochem Parasitol· December 2011

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The Leishmania donovani UMP synthase is essential for promastigote viability and has an unusual tetrameric structure that exhibits substrate-controlled oligomerization.
Jarrod B French, Phillip A Yates, D Radika Soysa, Jan M Boitz, Nicola S Carter

J Biol Chem· June 2011

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Characterization of amplicons that suppress the conditional lethal growth phenotype of a Leishmania donovani mutant lacking normal purine salvage mechanisms.
Audrey L Fulwiler, Jan M Boitz, Phillip A Yates, Nicola S Carter, Buddy Ullman

Mol Biochem Parasitol· January 2011

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Amplification of adenine phosphoribosyltransferase suppresses the conditionally lethal growth and virulence phenotype of Leishmania donovani mutants lacking both hypoxanthine-guanine and xanthine phosphoribosyltransferases.
Jan M Boitz, Buddy Ullman

J Biol Chem· June 2010

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Leishmania donovani ornithine decarboxylase is indispensable for parasite survival in the mammalian host.
Jan M Boitz, Phillip A Yates, Chelsey Kline, Upasna Gaur, Mary E Wilson

Infect Immun· February 2009

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Purine and pyrimidine metabolism in Leishmania.
Nicola S Carter, Phillip Yates, Cassandra S Arendt, Jan M Boitz, Buddy Ullman

Adv Exp Med Biol· April 2008

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Kinetic characterization of inosine monophosphate dehydrogenase of Leishmania donovani.
Fredrick Dobie, Amanda Berg, Jan M Boitz, Armando Jardim

Mol Biochem Parasitol· March 2007

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Functional characterization of nucleoside transporter gene replacements in Leishmania donovani.
Wei Liu, Jan M Boitz, Jon Galazka, Cassandra S Arendt, Nicola S Carter

Mol Biochem Parasitol· December 2006

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Leishmania donovani singly deficient in HGPRT, APRT or XPRT are viable in vitro and within mammalian macrophages.
Jan M Boitz, Buddy Ullman

Mol Biochem Parasitol· July 2006

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A conditional mutant deficient in hypoxanthine-guanine phosphoribosyltransferase and xanthine phosphoribosyltransferase validates the purine salvage pathway of Leishmania donovani.
Jan M Boitz, Buddy Ullman

J Biol Chem· June 2006

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