Publications by authors named "Jan Gronych"

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The age of adult pilocytic astrocytoma cells.
Natalia Voronina, Christian Aichmüller, Thorsten Kolb, Andrey Korshunov, Marina Ryzhova, Jan Gronych

Oncogene· April 2021

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DECIPHER pooled shRNA library screen identifies PP2A and FGFR signaling as potential therapeutic targets for diffuse intrinsic pontine gliomas.
Kathrin Schramm, Murat Iskar, Britta Statz, Natalie Jäger, Daniel Haag, Jan Gronych

Neuro Oncol· July 2019

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The Senescence-associated Secretory Phenotype Mediates Oncogene-induced Senescence in Pediatric Pilocytic Astrocytoma.
Juliane L Buhl, Florian Selt, Thomas Hielscher, Romain Guiho, Jonas Ecker, Jan Gronych

Clin Cancer Res· March 2019

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A novel cloning strategy for one-step assembly of multiplex CRISPR vectors.
Marc Zuckermann, Mario Hlevnjak, Haniyeh Yazdanparast, Marc Zapatka, David T W Jones, Jan Gronych

Sci Rep· November 2018

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Cited4 is a sex-biased mediator of the antidiabetic glitazone response in adipocyte progenitors.
Irem Bayindir-Buchhalter, Gretchen Wolff, Sarah Lerch, Tjeerd Sijmonsma, Maximilian Schuster, Jan Gronych

EMBO Mol Med· August 2018

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Chd7 is indispensable for mammalian brain development through activation of a neuronal differentiation programme.
Weijun Feng, Daisuke Kawauchi, Huiqin Körkel-Qu, Huan Deng, Elisabeth Serger, Jan Gronych

Nat Commun· March 2017

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Establishment and application of a novel patient-derived KIAA1549:BRAF-driven pediatric pilocytic astrocytoma model for preclinical drug testing.
Florian Selt, Juliane Hohloch, Thomas Hielscher, Felix Sahm, David Capper, Jan Gronych

Oncotarget· February 2017

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Applications of the CRISPR/Cas9 system in murine cancer modeling.
Marc Zuckermann, Daisuke Kawauchi, Jan Gronych

Brief Funct Genomics· January 2017

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TALEN/CRISPR-mediated engineering of a promoterless anti-viral RNAi hairpin into an endogenous miRNA locus.
Elena Senís, Stefan Mockenhaupt, Daniel Rupp, Tobias Bauer, Nagarajan Paramasivam, Jan Gronych

Nucleic Acids Res· January 2017

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"CRISPR" validation of recessive brain cancer genes in vivo.
Marc Zuckermann, Daisuke Kawauchi, Jan Gronych

Oncotarget· July 2015

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Somatic CRISPR/Cas9-mediated tumour suppressor disruption enables versatile brain tumour modelling.
Marc Zuckermann, Volker Hovestadt, Christiane B Knobbe-Thomsen, Marc Zapatka, Paul A Northcott, Jan Gronych

Nat Commun· June 2015

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Targeting self-renewal in high-grade brain tumors leads to loss of brain tumor stem cells and prolonged survival.
Zhe Zhu, Muhammad Amir Khan, Markus Weiler, Jonas Blaes, Leonie Jestaedt, Jan Gronych

Cell Stem Cell· August 2014

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Connect four with glioblastoma stem cell factors.
Jan Gronych, Stefan M Pfister, David T W Jones

Cell· April 2014

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Reduced H3K27me3 and DNA hypomethylation are major drivers of gene expression in K27M mutant pediatric high-grade gliomas.
Sebastian Bender, Yujie Tang, Anders M Lindroth, Volker Hovestadt, David T W Jones, Jan Gronych

Cancer Cell· November 2013

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Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma.
David T W Jones, Barbara Hutter, Natalie Jäger, Andrey Korshunov, Marcel Kool, Jan Gronych

Nat Genet· August 2013

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MAPK pathway activation in pilocytic astrocytoma.
David T W Jones, Jan Gronych, Peter Lichter, Olaf Witt, Stefan M Pfister

Cell Mol Life Sci· June 2012

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An activated mutant BRAF kinase domain is sufficient to induce pilocytic astrocytoma in mice.
Jan Gronych, Andrey Korshunov, Josephine Bageritz, Till Milde, Manfred Jugold

J Clin Invest· April 2011

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