Publications by authors named "Jonas Blaes"

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HLA-DQA1*05 Associates With Anti-Tumor Necrosis Factor Immunogenicity and Low Adalimumab Trough Concentrations in Inflammatory Bowel Disease Patients From the SERENE Ulcerative Colitis and Crohn's Disease Studies.
Mark Reppell, Xiuwen Zheng, Ingeborg Dreher, Jonas Blaes, Elina Regan

J Crohns Colitis· January 2025

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A first-in-human study of the novel immunology antibody-drug conjugate, ABBV-3373, in healthy participants.
Ronilda D'Cunha, Hartmut Kupper, Dilek Arikan, Weihan Zhao, David Carter, Jonas Blaes

Br J Clin Pharmacol· January 2024

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Assessing the Impact of Immunogenicity and Improving Prediction of Trough Concentrations: Population Pharmacokinetic Modeling of Adalimumab in Patients with Crohn's Disease and Ulcerative Colitis.
Ana Victoria Ponce-Bobadilla, Sven Stodtmann, Mong-Jen Chen, Insa Winzenborg, Sven Mensing, Jonas Blaes

Clin Pharmacokinet· April 2023

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A strategic approach to nonclinical immunogenicity assessment: a recommendation from the European Bioanalysis Forum.
Anna Laurén, Joanne Goodman, Jonas Blaes, John Cook, Kyra J Cowan

Bioanalysis· April 2021

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Inhibition of CD95/CD95L (FAS/FASLG) Signaling with APG101 Prevents Invasion and Enhances Radiation Therapy for Glioblastoma.
Jonas Blaes, Carina M Thomé, Philipp-Niclas Pfenning, Petra Rübmann, Felix Sahm

Mol Cancer Res· May 2018

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Tweety-Homolog 1 Drives Brain Colonization of Gliomas.
Erik Jung, Matthias Osswald, Jonas Blaes, Benedikt Wiestler, Felix Sahm

J Neurosci· July 2017

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Impact of Blood-Brain Barrier Integrity on Tumor Growth and Therapy Response in Brain Metastases.
Matthias Osswald, Jonas Blaes, Yunxiang Liao, Gergely Solecki, Miriam Gömmel

Clin Cancer Res· December 2016

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Prognostic relevance of miRNA-155 methylation in anaplastic glioma.
Maximilian Georg Schliesser, Rainer Claus, Thomas Hielscher, Christiane Grimm, Dieter Weichenhan, Jonas Blaes

Oncotarget· December 2016

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NDRG1 overexpressing gliomas are characterized by reduced tumor vascularization and resistance to antiangiogenic treatment.
Thomas Broggini, Marie Wüstner, Christoph Harms, Lena Stange, Jonas Blaes

Cancer Lett· October 2016

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Slowing down glioblastoma progression in mice by running or the anti-malarial drug dihydroartemisinin? Induction of oxidative stress in murine glioblastoma therapy.
Dieter Lemke, Hans-Werner Pledl, Markus Zorn, Manfred Jugold, Ed Green, Jonas Blaes

Oncotarget· August 2016

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Brain tumour cells interconnect to a functional and resistant network.
Matthias Osswald, Erik Jung, Felix Sahm, Gergely Solecki, Varun Venkataramani, Jonas Blaes

Nature· December 2015

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Glioma cell VEGFR-2 confers resistance to chemotherapeutic and antiangiogenic treatments in PTEN-deficient glioblastoma.
Tobias Kessler, Felix Sahm, Jonas Blaes, Matthias Osswald, Petra Rübmann

Oncotarget· October 2015

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Suppression of TDO-mediated tryptophan catabolism in glioblastoma cells by a steroid-responsive FKBP52-dependent pathway.
Martina Ott, Ulrike M Litzenburger, Katharina J Rauschenbach, Lukas Bunse, Katharina Ochs, Jonas Blaes

Glia· January 2015

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Primary glioblastoma cultures: can profiling of stem cell markers predict radiotherapy sensitivity?
Dieter Lemke, Markus Weiler, Jonas Blaes, Benedikt Wiestler, Leonie Jestaedt

J Neurochem· October 2014

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Targeting self-renewal in high-grade brain tumors leads to loss of brain tumor stem cells and prolonged survival.
Zhe Zhu, Muhammad Amir Khan, Markus Weiler, Jonas Blaes, Leonie Jestaedt

Cell Stem Cell· August 2014

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mTOR target NDRG1 confers MGMT-dependent resistance to alkylating chemotherapy.
Markus Weiler, Jonas Blaes, Stefan Pusch, Felix Sahm, Marcus Czabanka

Proc Natl Acad Sci U S A· January 2014

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mTORC 2:1 for chemotherapy sensitization in glioblastoma.
Wolfgang Wick, Jonas Blaes, Markus Weiler

Cancer Discov· November 2011

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