Publications by authors named "Jan Karlseder"

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Telomeres at the nexus of aging, tumor suppression, and inflammation: toward an understanding beyond senescence.
Samuel I Bloom, Jan Karlseder

Genes Dev· August 2025

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Telomere Crisis Shapes Cancer Evolution.
Joe Nassour, Jan Karlseder

Cold Spring Harb Perspect Biol· August 2025

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TRF1 relies on fork reversal to prevent fragility at human telomeres.
Mélina Vaurs, Eloïse Claude, Elia Zanella, Joana Rodrigues, Joe Nassour, Jan Karlseder

Nat Commun· July 2025

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Telomere function and regulation from mouse models to human ageing and disease.
Corey Jones-Weinert, Laura Mainz, Jan Karlseder

Nat Rev Mol Cell Biol· April 2025

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High resolution long-read telomere sequencing reveals dynamic mechanisms in aging and cancer.
Tobias T Schmidt, Carly Tyer, Preeyesh Rughani, Candy Haggblom, Jeffrey R Jones, Jan Karlseder

Nat Commun· June 2024

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Telomeres as hotspots for innate immunity and inflammation.
Joe Nassour, Sara Przetocka, Jan Karlseder

DNA Repair (Amst)· January 2024

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Hyperextended telomeres promote formation of C-circle DNA in telomerase positive human cells.
Celina Y Jones, Christopher L Williams, Sara Priego Moreno, Danna K Morris, Chiara Mondello, Jan Karlseder

J Biol Chem· May 2023

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TZAP overexpression induces telomere dysfunction and ALT-like activity in ATRX/DAXX-deficient cells.
Sara Priego Moreno, Javier Miralles Fusté, Melanie Kaiser, Julia Su Zhou Li, Joe Nassour, Jan Karlseder

iScience· April 2023

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Telomere-to-mitochondria signalling by ZBP1 mediates replicative crisis.
Joe Nassour, Lucia Gutierrez Aguiar, Adriana Correia, Tobias T Schmidt, Laura Mainz, Jan Karlseder

Nature· February 2023

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Hyperextended telomeres promote C-circle formation in telomerase positive human cells.
Celina Y Jones, Christopher L Williams, Sara P Moreno, Danna K Morris, Chiara Mondello, Jan Karlseder

bioRxiv· January 2023

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Telomeres and Cancer: Resolving the Paradox.
Joe Nassour, Tobias T Schmidt, Jan Karlseder

Annu Rev Cancer Biol· March 2021

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A stem cell reporter based platform to identify and target drug resistant stem cells in myeloid leukemia.
Kyle Spinler, Jeevisha Bajaj, Takahiro Ito, Bryan Zimdahl, Michael Hamilton, Jan Karlseder

Nat Commun· November 2020

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Replication stress induces mitotic death through parallel pathways regulated by WAPL and telomere deprotection.
V Pragathi Masamsetti, Ronnie Ren Jie Low, Ka Sin Mak, Aisling O'Connor, Chris D Riffkin, Jan Karlseder

Nat Commun· September 2019

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Autophagic cell death restricts chromosomal instability during replicative crisis.
Joe Nassour, Robert Radford, Adriana Correia, Javier Miralles Fusté, Brigitte Schoell, Jan Karlseder

Nature· January 2019

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Regulation of DNA repair pathway choice in S and G2 phases by the NHEJ inhibitor CYREN.
Nausica Arnoult, Adriana Correia, Jiao Ma, Anna Merlo, Sara Garcia-Gomez, Jan Karlseder

Nature· September 2017

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TZAP: A telomere-associated protein involved in telomere length control.
Julia Su Zhou Li, Javier Miralles Fusté, Tatevik Simavorian, Cristina Bartocci, Jill Tsai, Jan Karlseder

Science· February 2017

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A balance between elongation and trimming regulates telomere stability in stem cells.
Teresa Rivera, Candy Haggblom, Sandro Cosconati, Jan Karlseder

Nat Struct Mol Biol· January 2017

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Complex interactions between the DNA-damage response and mammalian telomeres.
Nausica Arnoult, Jan Karlseder

Nat Struct Mol Biol· November 2015

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Cell death during crisis is mediated by mitotic telomere deprotection.
Makoto T Hayashi, Anthony J Cesare, Teresa Rivera, Jan Karlseder

Nature· June 2015

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A genomics approach identifies senescence-specific gene expression regulation.
Daniel H Lackner, Makoto T Hayashi, Anthony J Cesare, Jan Karlseder

Aging Cell· October 2014

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Modern genome editing meets telomeres: the many functions of TPP1.
Jan Karlseder

Genes Dev· September 2014

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ALT telomeres borrow from meiosis to get moving.
Nausica Arnoult, Jan Karlseder

Cell· September 2014

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Rapid induction of alternative lengthening of telomeres by depletion of the histone chaperone ASF1.
Roderick J O'Sullivan, Nausica Arnoult, Daniel H Lackner, Liana Oganesian, Candy Haggblom, Jan Karlseder

Nat Struct Mol Biol· February 2014

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The telomere deprotection response is functionally distinct from the genomic DNA damage response.
Anthony J Cesare, Makoto T Hayashi, Laure Crabbe, Jan Karlseder

Mol Cell· July 2013

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C. elegans survivors without telomerase.
Daniel H Lackner, Jan Karlseder

Worm· January 2013

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