Publications by authors named "Jan Sun"

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Small-molecule inhibition of kinesin KIF18A reveals a mitotic vulnerability enriched in chromosomally unstable cancers.
Marc Payton, Brian Belmontes, Kelly Hanestad, Jodi Moriguchi, Kui Chen, Jan Sun

Nat Cancer· January 2024

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Targeting the Mitotic Kinesin KIF18A in Chromosomally Unstable Cancers: Hit Optimization Toward an In Vivo Chemical Probe.
Nuria A Tamayo, Matthew P Bourbeau, Jennifer R Allen, Kate S Ashton, Jian Jeffrey Chen, Jan Sun

J Med Chem· March 2022

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AMG 176, a Selective MCL1 Inhibitor, Is Effective in Hematologic Cancer Models Alone and in Combination with Established Therapies.
Sean Caenepeel, Sean P Brown, Brian Belmontes, Gordon Moody, Kathleen S Keegan, Jan Sun

Cancer Discov· December 2018

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Therapeutic Antibody Targeting Tumor- and Osteoblastic Niche-Derived Jagged1 Sensitizes Bone Metastasis to Chemotherapy.
Hanqiu Zheng, Yangjin Bae, Sabine Kasimir-Bauer, Rebecca Tang, Jin Chen, Jan Sun

Cancer Cell· December 2017

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Notch1 signalling regulates endothelial proliferation and apoptosis in pulmonary arterial hypertension.
Swati Dabral, Xia Tian, Baktybek Kojonazarov, Rajkumar Savai, Hossein Ardeschir Ghofrani, Jan Sun

Eur Respir J· October 2016

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Alcohol intake and Helicobacter pylori infection: a dose-response meta-analysis of observational studies.
Shi-Yu Liu, Xin-Chen Han, Jan Sun, Guang-Xia Chen, Xiao-Ying Zhou

Infect Dis (Lond)· April 2016

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Biochemical characterization of AMG 102: a neutralizing, fully human monoclonal antibody to human and nonhuman primate hepatocyte growth factor.
Teresa L Burgess, Jan Sun, Susanne Meyer, Trace S Tsuruda, Jilin Sun

Mol Cancer Ther· February 2010

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Therapeutic potential of hepatocyte growth factor/scatter factor neutralizing antibodies: inhibition of tumor growth in both autocrine and paracrine hepatocyte growth factor/scatter factor:c-Met-driven models of leiomyosarcoma.
Chong-Feng Gao, Qian Xie, Yu-Wen Zhang, Yanli Su, Ping Zhao, Jan Sun

Mol Cancer Ther· October 2009

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AMG 102, a fully human anti-hepatocyte growth factor/scatter factor neutralizing antibody, enhances the efficacy of temozolomide or docetaxel in U-87 MG cells and xenografts.
H Toni Jun, Jan Sun, Karen Rex, Robert Radinsky, Richard Kendall

Clin Cancer Res· November 2007

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c-Met ectodomain shedding rate correlates with malignant potential.
Gagani Athauda, Alessio Giubellino, Jonathan A Coleman, Christine Horak, Patricia S Steeg, Jan Sun

Clin Cancer Res· July 2006

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Fully human monoclonal antibodies to hepatocyte growth factor with therapeutic potential against hepatocyte growth factor/c-Met-dependent human tumors.
Teresa Burgess, Angela Coxon, Susanne Meyer, Jan Sun, Karen Rex, Jilin Sun

Cancer Res· February 2006

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Membrane destabilization by ricin.
Jan Sun, Elena E Pohl, Oxana O Krylova, Eberhard Krause, Igor I Agapov

Eur Biophys J· November 2004

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