Publications by authors named "Janet Griffiths"

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Biomarkers and clinical outcomes after tezepelumab cessation: Extended follow-up from the 2-year DESTINATION study.
Christopher E Brightling, Marco Caminati, Jean-Pierre Llanos, Scott Caveney, Ales Kotalik, Janet M Griffiths

Ann Allergy Asthma Immunol· September 2024

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Tezepelumab reduces exacerbations across all seasons in patients with severe, uncontrolled asthma (NAVIGATOR).
Ian D Pavord, Flavia C L Hoyte, Andrew W Lindsley, Christopher S Ambrose, Joseph D Spahn, Janet M Griffiths

Ann Allergy Asthma Immunol· November 2023

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Tezepelumab for the treatment of severe asthma: a plain language summary of the PATHWAY and NAVIGATOR studies.
Jonathan Corren, Andrew Menzies-Gow, Johan Bimmel, Anthony McGuinness, Gun Almqvist, Janet M Griffiths

Immunotherapy· November 2023

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Tezepelumab and Mucus Plugs in Patients with Moderate-to-Severe Asthma.
Lars H Nordenmark, Åsa Hellqvist, Claire Emson, Sarah Diver, Celeste Porsbjerg, Janet M Griffiths

NEJM Evid· October 2023

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Efficacy of Tezepelumab in Severe, Uncontrolled Asthma: Pooled Analysis of the PATHWAY and NAVIGATOR Clinical Trials.
Jonathan Corren, Andrew Menzies-Gow, Geoffrey Chupp, Elliot Israel, Stephanie Korn, Janet M Griffiths

Am J Respir Crit Care Med· July 2023

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Reply to Lipworth and Chan.
Christopher S Ambrose, Elliot Israel, Karin Bowen, Jean-Pierre Llanos, Neil Martin, Janet M Griffiths

Am J Respir Crit Care Med· July 2023

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Efficacy of tezepelumab in patients with evidence of severe allergic asthma: Results from the phase 3 NAVIGATOR study.
Jonathan Corren, Christopher S Ambrose, Janet M Griffiths, Åsa Hellqvist, Andrew W Lindsley

Clin Exp Allergy· April 2023

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Feno differentiates epithelial gene expression clusters: Exploratory analysis from the MESOS randomized controlled trial.
Sarah Diver, Sriram Sridhar, Latifa C Khalfaoui, Richard J Russell, Claire Emson, Janet M Griffiths

J Allergy Clin Immunol· October 2022

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Evaluation of the oral corticosteroid-sparing effect of tezepelumab in adults with oral corticosteroid-dependent asthma (SOURCE): a randomised, placebo-controlled, phase 3 study.
Michael E Wechsler, Andrew Menzies-Gow, Christopher E Brightling, Piotr Kuna, Stephanie Korn, Janet M Griffiths

Lancet Respir Med· July 2022

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Baseline type 2 biomarker levels and response to tezepelumab in severe asthma.
Jonathan Corren, Tuyet-Hang Pham, Esther Garcia Gil, Kinga Sałapa, Pin Ren, Janet M Griffiths

Allergy· June 2022

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Efficacy of Tezepelumab in Patients with Severe, Uncontrolled Asthma and Perennial Allergy.
Jonathan Corren, Christopher S Ambrose, Kinga Sałapa, Stephanie L Roseti, Janet M Griffiths

J Allergy Clin Immunol Pract· December 2021

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Tezepelumab normalizes serum interleukin-5 and -13 levels in patients with severe, uncontrolled asthma.
Tuyet-Hang Pham, Claudia Chen, Gene Colice, Jane R Parnes, Janet M Griffiths

Ann Allergy Asthma Immunol· December 2021

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Pharmacokinetic and Pharmacodynamic Modeling of Tezepelumab to Guide Phase 3 Dose Selection for Patients With Severe Asthma.
Neang Ly, Yanan Zheng, Janet M Griffiths, Rene van der Merwe, Balaji Agoram

J Clin Pharmacol· July 2021

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Tezepelumab in Adults and Adolescents with Severe, Uncontrolled Asthma.
Andrew Menzies-Gow, Jonathan Corren, Arnaud Bourdin, Geoffrey Chupp, Elliot Israel, Janet M Griffiths

N Engl J Med· May 2021

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Tezepelumab improves patient-reported outcomes in patients with severe, uncontrolled asthma in PATHWAY.
Jonathan Corren, Esther Garcia Gil, Janet M Griffiths, Jane R Parnes, Rene van der Merwe

Ann Allergy Asthma Immunol· February 2021

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SOURCE: a phase 3, multicentre, randomized, double-blind, placebo-controlled, parallel group trial to evaluate the efficacy and safety of tezepelumab in reducing oral corticosteroid use in adults with oral corticosteroid dependent asthma.
Michael E Wechsler, Gene Colice, Janet M Griffiths, Gun Almqvist, Tor Skärby

Respir Res· October 2020

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NAVIGATOR: a phase 3 multicentre, randomized, double-blind, placebo-controlled, parallel-group trial to evaluate the efficacy and safety of tezepelumab in adults and adolescents with severe, uncontrolled asthma.
Andrew Menzies-Gow, Gene Colice, Janet M Griffiths, Gun Almqvist, Sandhia Ponnarambil

Respir Res· October 2020

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Thymic stromal lymphopoietin: its role and potential as a therapeutic target in asthma.
Gail M Gauvreau, Roma Sehmi, Christopher S Ambrose, Janet M Griffiths

Expert Opin Ther Targets· August 2020

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Humanised effector-null FcγRIIA antibody inhibits immune complex-mediated proinflammatory responses.
Bo Chen, Katherine A Vousden, Brian Naiman, Sean Turman, Hong Sun, Janet Griffiths

Ann Rheum Dis· February 2019

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Tezepelumab in Adults with Uncontrolled Asthma.
Jonathan Corren, Jane R Parnes, Liangwei Wang, May Mo, Stephanie L Roseti, Janet M Griffiths

N Engl J Med· September 2017

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Guidelines for the development of local standards of oral health care for people with dementia.
Janice Fiske, Heather Frenkel, Janet Griffiths, Vicki Jones,

Gerodontology· December 2006

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Fluid mechanics, cell distribution, and environment in CellCube bioreactors.
John G Auniņs, Brett Bader, Anthony Caola, Janet Griffiths, Maayan Katz

Biotechnol Prog· October 2003

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Colonic manometry in children with defecatory disorders. role in diagnosis and management.
Licia Pensabene, Nader N Youssef, Janet M Griffiths, Carlo Di Lorenzo

Am J Gastroenterol· May 2003

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Multiple sclerosis and oral care.
Janice Fiske, Janet Griffiths, Shelagh Thompson

Dent Update· November 2002

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Management of intractable constipation with antegrade enemas in neurologically intact children.
Nader N Youssef, Edward Barksdale Jr, Janet M Griffiths, Alejandro F Flores, Carlo Di Lorenzo

J Pediatr Gastroenterol Nutr· April 2002

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