Publications by authors named "Janet Jackman"

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An agonistic anti-signal regulatory protein α antibody for chronic inflammatory diseases.
Markus M Xie, Bingbing Dai, Jason A Hackney, Tianhe Sun, Juan Zhang, Janet K Jackman

Cell Rep Med· August 2023

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Dual antibody inhibition of KLK5 and KLK7 for Netherton syndrome and atopic dermatitis.
Joseph Chavarria-Smith, Cecilia P C Chiu, Janet K Jackman, Jianping Yin, Juan Zhang

Sci Transl Med· December 2022

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Genome-wide association study identifies kallikrein 5 in type 2 inflammation-low asthma.
Janet K Jackman, Amy Stockwell, David F Choy, Markus M Xie, Peipei Lu

J Allergy Clin Immunol· October 2022

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Bivalent antibody pliers inhibit β-tryptase by an allosteric mechanism dependent on the IgG hinge.
Henry R Maun, Rajesh Vij, Benjamin T Walters, Ashley Morando, Janet K Jackman

Nat Commun· December 2020

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An Allosteric Anti-tryptase Antibody for the Treatment of Mast Cell-Mediated Severe Asthma.
Henry R Maun, Janet K Jackman, David F Choy, Kelly M Loyet, Tracy L Staton

Cell· January 2020

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An Allosteric Anti-tryptase Antibody for the Treatment of Mast Cell-Mediated Severe Asthma.
Henry R Maun, Janet K Jackman, David F Choy, Kelly M Loyet, Tracy L Staton

Cell· October 2019

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Lung-restricted inhibition of Janus kinase 1 is effective in rodent models of asthma.
Hart S Dengler, Xiumin Wu, Ivan Peng, Cornelia H Rinderknecht, Youngsu Kwon, Janet Jackman

Sci Transl Med· November 2018

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A CEACAM6-High Airway Neutrophil Phenotype and CEACAM6-High Epithelial Cells Are Features of Severe Asthma.
Aarti Shikotra, David F Choy, Salman Siddiqui, Greer Arthur, Deepti R Nagarkar, Janet Jackman

J Immunol· April 2017

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Inhibition of the kinase ITK in a mouse model of asthma reduces cell death and fails to inhibit the inflammatory response.
Yonglian Sun, Ivan Peng, Joshua D Webster, Eric Suto, Justin Lesch, Janet Jackman

Sci Signal· December 2015

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Conditional Deletion of NF-κB-Inducing Kinase (NIK) in Adult Mice Disrupts Mature B Cell Survival and Activation.
Hans D Brightbill, Janet K Jackman, Eric Suto, Heather Kennedy, Charles Jones

J Immunol· August 2015

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TH2 and TH17 inflammatory pathways are reciprocally regulated in asthma.
David F Choy, Kevin M Hart, Lee A Borthwick, Aarti Shikotra, Deepti R Nagarkar, Janet Jackman

Sci Transl Med· August 2015

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Endogenously expressed IL-13Rα2 attenuates IL-13-mediated responses but does not activate signaling in human lung fibroblasts.
Sanjay Chandriani, Daryle J DePianto, Elsa N N'Diaye, Alexander R Abbas, Janet Jackman

J Immunol· July 2014

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Development of a human IgG4 bispecific antibody for dual targeting of interleukin-4 (IL-4) and interleukin-13 (IL-13) cytokines.
Christoph Spiess, Jack Bevers, Janet Jackman, Nancy Chiang, Gerald Nakamura

J Biol Chem· September 2013

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LUZ-Y, a novel platform for the mammalian cell production of full-length IgG-bispecific antibodies.
Bernd J Wranik, Erin L Christensen, Gabriele Schaefer, Janet K Jackman, Andrew C Vendel

J Biol Chem· December 2012

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Increased expression of immunoreactive thymic stromal lymphopoietin in patients with severe asthma.
Aarti Shikotra, David F Choy, Chandra M Ohri, Emma Doran, Claire Butler, Janet Jackman

J Allergy Clin Immunol· January 2012

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Lung gene expression in a rhesus allergic asthma model correlates with physiologic parameters of disease and exhibits common and distinct pathways with human asthma and a mouse asthma model.
Alexander R Abbas, Janet K Jackman, Sherron L Bullens, Sarah M Davis, David F Choy

Am J Pathol· October 2011

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Development of a two-part strategy to identify a therapeutic human bispecific antibody that inhibits IgE receptor signaling.
Janet Jackman, Yongmei Chen, Arthur Huang, Barbara Moffat, Justin M Scheer

J Biol Chem· July 2010

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Antibodies specific for a segment of human membrane IgE deplete IgE-producing B cells in humanized mice.
Hans D Brightbill, Surinder Jeet, Zhonghua Lin, Donghong Yan, Meijuan Zhou, Janet Jackman

J Clin Invest· June 2010

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