Publications by authors named "Janet Thornton"

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Measuring catalytic mechanism similarity - a new approach to study enzyme function and evolution.
Antonio J M Ribeiro, Ioannis G Riziotis, Neera Borkakoti, Pedro A Fernandes, Maria J Ramos, Janet M Thornton

FEBS J· August 2025

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Analysis of FAIMS for the study of affinity-purified protein complexes using the orbitrap ascend tribrid mass spectrometer.
Pratik Goswami, Joseph Cesare, Michaella J Rekowski, Zachary Clark, Janet Thornton

Mol Omics· July 2025

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A structural perspective on enzymes and their catalytic mechanisms.
Neera Borkakoti, António J M Ribeiro, Janet M Thornton

Curr Opin Struct Biol· June 2025

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Lineage-specific patterns in the Moraceae family allow identification of convergent P450 enzymes involved in furanocoumarin biosynthesis.
Alexandre Bouillé, Romain Larbat, Rashmi Kumari, Alexandre Olry, Clément Charles, Janet Thornton

New Phytol· March 2025

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Paradigms of convergent evolution in enzymes.
Ioannis G Riziotis, Jenny C Kafas, Gabriel Ong, Neera Borkakoti, António J M Ribeiro, Janet M Thornton

FEBS J· February 2025

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Analysis of FAIMS for the Study of Affinity-Purified Protein Complexes Using the Orbitrap Ascend Tribrid Mass Spectrometer.
Pratik Goswami, Joseph Cesare, Michaella J Rekowski, Zachary Clark, Janet Thornton

bioRxiv· December 2024

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Distinct Regions within SAP25 Recruit O-Linked Glycosylation, DNA Demethylation, and Ubiquitin Ligase and Hydrolase Activities to the Sin3/HDAC Complex.
Pratik Goswami, Charles A S Banks, Janet Thornton, Bethany D Bengs, Mihaela E Sardiu

J Proteome Res· November 2024

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Distinct regions within SAP25 recruit O-linked glycosylation, DNA demethylation, and ubiquitin ligase and hydrolase activities to the Sin3/HDAC complex.
Pratik Goswami, Charles A S Banks, Janet Thornton, Bethany Bengs, Mihaela E Sardiu

bioRxiv· March 2024

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Enzyme function and evolution through the lens of bioinformatics.
Antonio J M Ribeiro, Ioannis G Riziotis, Neera Borkakoti, Janet M Thornton

Biochem J· November 2023

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The 3D Modules of Enzyme Catalysis: Deconstructing Active Sites into Distinct Functional Entities.
Ioannis G Riziotis, António J M Ribeiro, Neera Borkakoti, Janet M Thornton

J Mol Biol· October 2023

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EzMechanism: an automated tool to propose catalytic mechanisms of enzyme reactions.
Antonio J M Ribeiro, Ioannis G Riziotis, Jonathan D Tyzack, Neera Borkakoti, Janet M Thornton

Nat Methods· October 2023

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The mission to ensure continued funding for excellent basic research.
Angus I Lamond, Ivan Dikic, Andre Nussenzweig, Christoph W Müller, Janet M Thornton

EMBO Rep· July 2023

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Author Correction: Temporal changes in the gene expression heterogeneity during brain development and aging.
Ulaş Işıldak, Mehmet Somel, Janet M Thornton, Handan Melike Dönertaş

Sci Rep· June 2023

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SelectBCM tool: a batch evaluation framework to select the most appropriate batch-correction methods for bulk transcriptome analysis.
Madhulika Mishra, Lucas Barck, Pablo Moreno, Guillaume Heger, Yuyao Song, Janet M Thornton

NAR Genom Bioinform· March 2023

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AlphaFold2 protein structure prediction: Implications for drug discovery.
Neera Borkakoti, Janet M Thornton

Curr Opin Struct Biol· February 2023

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Mapping the Constrained Coding Regions in the Human Genome to Their Corresponding Proteins.
Marcia A Hasenahuer, Alba Sanchis-Juan, Roman A Laskowski, James A Baker, James D Stephenson, Janet M Thornton

J Mol Biol· January 2023

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Using mechanism similarity to understand enzyme evolution.
António J M Ribeiro, Ioannis G Riziotis, Jonathan D Tyzack, Neera Borkakoti, Janet M Thornton

Biophys Rev· December 2022

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A structural biology community assessment of AlphaFold2 applications.
Mehmet Akdel, Douglas E V Pires, Eduard Porta Pardo, Jürgen Jänes, Arthur O Zalevsky, Janet M Thornton

Nat Struct Mol Biol· November 2022

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The Enzyme Portal: an integrative tool for enzyme information and analysis.
Rossana Zaru, Joseph Onwubiko, Antonio J M Ribeiro, Keeva Cochrane, Jonathan D Tyzack, Janet M Thornton

FEBS J· October 2022

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GRaSP-web: a machine learning strategy to predict binding sites based on residue neighborhood graphs.
Charles A Santana, Sandro C Izidoro, Raquel C de Melo-Minardi, Jonathan D Tyzack, António J M Ribeiro, Janet M Thornton

Nucleic Acids Res· July 2022

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Capturing the geometry, function, and evolution of enzymes with 3D templates.
Ioannis G Riziotis, Janet M Thornton

Protein Sci· July 2022

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Conformational Variation in Enzyme Catalysis: A Structural Study on Catalytic Residues.
Ioannis G Riziotis, António J M Ribeiro, Neera Borkakoti, Janet M Thornton

J Mol Biol· April 2022

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PDBsum extras: SARS-CoV-2 and AlphaFold models.
Roman A Laskowski, Janet M Thornton

Protein Sci· January 2022

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The impact of AlphaFold2 one year on.
David T Jones, Janet M Thornton

Nat Methods· January 2022

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AlphaFold heralds a data-driven revolution in biology and medicine.
Janet M Thornton, Roman A Laskowski, Neera Borkakoti

Nat Med· October 2021

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