Publications by authors named "Janice Chambers"

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Model acetylcholinesterase-Fc fusion glycoprotein biotechnology system for the manufacture of an organophosphorus toxicant bioscavenging countermeasure.
Thomas G Biel, Talia Faison, Alicia M Matthews, Uriel Ortega-Rodriguez, Vincent M Falkowski, Janice E Chambers

Bioeng Transl Med· September 2024

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Reactivation by novel pyridinium oximes of rat serum and skeletal muscle acetylcholinesterase inhibited by organophosphates.
Joshua P Bennett, Edward C Meek, Janice E Chambers

J Biochem Mol Toxicol· July 2024

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The in silico identification of novel broad-spectrum antidotes for poisoning by organophosphate anticholinesterases.
Sohaib Habiballah, Janice Chambers, Edward Meek, Brad Reisfeld

J Comput Aided Mol Des· December 2023

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The in silico identification of novel broad-spectrum antidotes for poisoning by organophosphate anticholinesterases.
Sohaib Habiballah, Janice Chambers, Edward Meek, Brad Reisfeld

Res Sq· July 2023

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Pharmacokinetics of three novel pyridinium aldoxime acetylcholinesterase reactivators in female rats.
Brian S Backer, Edward C Meek, Matthew K Ross, Janice E Chambers

Toxicol Appl Pharmacol· July 2022

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Effect of high fat diet on the toxicokinetics and toxicodynamics of chlorpyrifos following acute exposure in male C57BL/6J mice.
Sandeep Kondakala, Matthew K Ross, Janice E Chambers, George E Howell

J Biochem Mol Toxicol· June 2022

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effect of DDE exposure on the regulation of B-TC-6 pancreatic beta cell insulin secretion: a potential role in beta cell dysfunction and type 2 diabetes mellitus.
Antonio B Ward, Mary B Dail, Janice E Chambers

Toxicol Mech Methods· November 2021

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Inhibition Kinetics of 16 Organophosphorus Pesticides or Their Active Metabolites on Erythrocyte Acetylcholinesterase From Humans and Rats.
Edward C Meek, Richard Reiss, John Allen Crow, Janice E Chambers

Toxicol Sci· September 2021

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Effects of novel brain-penetrating oxime acetylcholinesterase reactivators on sarin surrogate-induced changes in rat brain gene expression.
Mary E Dail, Meghan L M Brino, Janice E Chambers

J Biochem Mol Toxicol· June 2021

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In vitro age-related differences in rats to organophosphates.
Edward C Meek, Russell L Carr, Janice E Chambers

Toxicol In Vitro· April 2021

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Reactivation of organophosphate-inhibited serum butyrylcholinesterase by novel substituted phenoxyalkyl pyridinium oximes and traditional oximes.
Royce H Nichols, Janice E Chambers

Toxicology· March 2021

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Novel pyridinium oximes enhance 24-h survivability against a lethal dose of nerve agent surrogate in adult female rats.
Jason M Garcia, Edward C Meek, Janice E Chambers

Toxicology· December 2020

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Central neuroprotection demonstrated by novel oxime countermeasures to nerve agent surrogates.
Janice E Chambers, Edward C Meek

Ann N Y Acad Sci· November 2020

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Oxime-mediated reactivation of organophosphate-inhibited acetylcholinesterase with emphasis on centrally-active oximes.
Janice E Chambers, Mary B Dail, Edward C Meek

Neuropharmacology· September 2020

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Association of serum levels of - Dichlorodiphenyldichloroethylene (DDE) with type 2 diabetes in African American and Caucasian adult men from agricultural (Delta) and non-agricultural (non-Delta) regions of Mississippi.
Edward C Meek, Dana Dale Jones, J Allen Crow, Robert W Wills, William H Cooke, Janice E Chambers

J Toxicol Environ Health A· May 2020

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Novel centrally active oxime reactivators of acetylcholinesterase inhibited by surrogates of sarin and VX.
Janice E Chambers, Edward C Meek

Neurobiol Dis· January 2020

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In vitro P-glycoprotein activity does not completely explain in vivo efficacy of novel centrally effective oxime acetylcholinesterase reactivators.
Mary Beth Dail, Edward Caldwell Meek, Howard Wayne Chambers, Janice Elaine Chambers

Drug Chem Toxicol· July 2019

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Novel Brain-Penetrating Oxime Acetylcholinesterase Reactivators Attenuate Organophosphate-Induced Neuropathology in the Rat Hippocampus.
Mary B Dail, Charles A Leach, Edward C Meek, Alicia K Olivier, Ronald B Pringle, Janice E Chambers

Toxicol Sci· June 2019

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Neuroprotection From Organophosphate-Induced Damage by Novel Phenoxyalkyl Pyridinium Oximes in Rat Brain.
Ronald B Pringle, Edward C Meek, Howard W Chambers, Janice E Chambers

Toxicol Sci· December 2018

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A case-control study: The association of serum paraoxonase 1 activity and concentration with the development of type 2 diabetes mellitus.
J Allen Crow, Edward C Meek, Robert W Wills, Janice E Chambers

Diabetes Metab Res Rev· March 2018

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Effects of Chlorpyrifos or Methyl Parathion on Regional Cholinesterase Activity and Muscarinic Receptor Subtype Binding in Juvenile Rat Brain.
Shirley X Guo-Ross, Edward C Meek, Janice E Chambers, Russell L Carr

J Toxicol Pharmacol· December 2017

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Population-relevant endpoints in the evaluation of endocrine-active substances (EAS) for ecotoxicological hazard and risk assessment.
Mary S Marty, Amy Blankinship, Janice Chambers, Lisa Constantine, Werner Kloas

Integr Environ Assess Manag· March 2017

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Recommended approaches to the scientific evaluation of ecotoxicological hazards and risks of endocrine-active substances.
Peter Matthiessen, Gerald T Ankley, Ronald C Biever, Poul Bjerregaard, Christopher Borgert, Janice Chambers

Integr Environ Assess Manag· March 2017

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In Vitro effect of DDE exposure on the regulation of lipid metabolism and secretion in McA-RH7777 hepatocytes: A potential role in dyslipidemia which may increase the risk of type 2 diabetes mellitus.
Antonio B Ward, Mary B Dail, Janice E Chambers

Toxicol In Vitro· December 2016

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In vitro characterization of pralidoxime transport and acetylcholinesterase reactivation across MDCK cells and stem cell-derived human brain microvascular endothelial cells (BC1-hBMECs).
Erin Gallagher, Il Minn, Janice E Chambers, Peter C Searson

Fluids Barriers CNS· July 2016

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