Publications by authors named "Jason D Ulrich"

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Lymphoid gene expression supports neuroprotective microglia function.
Pinar Ayata, Jessica M Crowley, Matthew F Challman, Vinaya Sahasrabuddhe, Maud Gratuze, Jason D Ulrich

Nature· December 2025

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Context matters: Conflicting roles of interferon-γ signaling in CNS diseases.
Jonathan Nulman, Jason D Ulrich, David M Holtzman

Curr Opin Neurobiol· December 2025

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ApoE-calypse tau: ApoE-tau synergy in Alzheimer's disease.
Matthew Paul Lennol, Chiara Bordier, Léana Kamelher, Jason D Ulrich, David M Holtzman

J Exp Med· October 2025

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Maternal inheritance suppresses CAA and amyloid plaques in 5xFAD (Tg7031)/APOE4 mice.
Fareeha Saadi, Ilia V Katritch, Samira Parhizkar, Brisa Lugo, Yoonho Cho, Jason D Ulrich

Neuron· September 2025

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Inhaled xenon modulates microglia and ameliorates disease in mouse models of amyloidosis and tauopathy.
Wesley Brandao, Nimansha Jain, Zhuoran Yin, Kilian L Kleemann, Madison Carpenter, Jason D Ulrich

Sci Transl Med· January 2025

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Author Correction: Microglia-mediated T cell infiltration drives neurodegeneration in tauopathy.
Xiaoying Chen, Maria Firulyova, Melissa Manis, Jasmin Herz, Igor Smirnov, Jason D Ulrich

Nature· October 2024

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Advancements in APOE and dementia research: Highlights from the 2023 AAIC Advancements: APOE conference.
Courtney M Kloske, Michael E Belloy, Elizabeth E Blue, Gregory R Bowman, Maria C Carrillo, Jason D Ulrich

Alzheimers Dement· September 2024

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Amelioration of Tau and ApoE4-linked glial lipid accumulation and neurodegeneration with an LXR agonist.
Alexandra Litvinchuk, Jung H Suh, Jing L Guo, Karin Lin, Sonnet S Davis, Jason D Ulrich

Neuron· June 2024

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Seq-ing mechanisms behind types of Alzheimer's disease.
Yun Chen, Jason D Ulrich

Neuron· June 2024

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Apolipoprotein E secreted by astrocytes forms antiparallel dimers in discoidal lipoproteins.
Michael R Strickland, Michael J Rau, Brock Summers, Katherine Basore, John Wulf, Jason D Ulrich

Neuron· April 2024

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Cholesterol 25-hydroxylase mediates neuroinflammation and neurodegeneration in a mouse model of tauopathy.
Danira Toral-Rios, Justin M Long, Jason D Ulrich, Jinsheng Yu, Michael R Strickland

J Exp Med· April 2024

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Rapid sequential clustering of NMDARs, CaMKII, and AMPARs upon activation of NMDARs at developing synapses.
Yucui Chen, Shangming Liu, Ariel A Jacobi, Grace Jeng, Jason D Ulrich

Front Synaptic Neurosci· April 2024

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Amelioration of Tau and ApoE4-linked glial lipid accumulation and neurodegeneration with an LXR agonist.
Alexandra Litvinchuk, Jung H Suh, Jing L Guo, Karin Lin, Sonnet S Davis, Jason D Ulrich

Neuron· February 2024

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APOE3ch alters microglial response and suppresses Aβ-induced tau seeding and spread.
Yun Chen, Sihui Song, Samira Parhizkar, Jennifer Lord, Yiyang Zhu, Jason D Ulrich

Cell· January 2024

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Parenchymal border macrophages regulate tau pathology and tau-mediated neurodegeneration.
Antoine Drieu, Siling Du, Michal Kipnis, Megan E Bosch, Jasmin Herz, Jason D Ulrich

Life Sci Alliance· November 2023

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APOE-ε4 synergizes with sleep disruption to accelerate Aβ deposition and Aβ-associated tau seeding and spreading.
Chanung Wang, Aishwarya Nambiar, Michael R Strickland, Choonghee Lee, Samira Parhizkar, Jason D Ulrich

J Clin Invest· July 2023

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TREM2 inhibition triggers antitumor cell activity of myeloid cells in glioblastoma.
Rui Sun, Rowland Han, Colin McCornack, Saad Khan, G Travis Tabor, Jason D Ulrich

Sci Adv· May 2023

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Microglia-mediated T cell infiltration drives neurodegeneration in tauopathy.
Xiaoying Chen, Maria Firulyova, Melissa Manis, Jasmin Herz, Igor Smirnov, Jason D Ulrich

Nature· March 2023

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Chronic TREM2 activation exacerbates Aβ-associated tau seeding and spreading.
Nimansha Jain, Caroline A Lewis, Jason D Ulrich, David M Holtzman

J Exp Med· January 2023

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TREM2-independent microgliosis promotes tau-mediated neurodegeneration in the presence of ApoE4.
Maud Gratuze, Johannes C M Schlachetzki, Ricardo D'Oliveira Albanus, Nimansha Jain, Brenna Novotny, Jason D Ulrich

Neuron· January 2023

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ApoE isoform- and microbiota-dependent progression of neurodegeneration in a mouse model of tauopathy.
Dong-Oh Seo, David O'Donnell, Nimansha Jain, Jason D Ulrich, Jasmin Herz

Science· January 2023

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TREM2 and microglia exosomes: a potential highway for pathological tau.
Nimansha Jain, Jason D Ulrich

Mol Neurodegener· November 2022

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Selective reduction of astrocyte apoE3 and apoE4 strongly reduces Aβ accumulation and plaque-related pathology in a mouse model of amyloidosis.
Thomas E Mahan, Chao Wang, Xin Bao, Ankit Choudhury, Jason D Ulrich

Mol Neurodegener· February 2022

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Overexpressing low-density lipoprotein receptor reduces tau-associated neurodegeneration in relation to apoE-linked mechanisms.
Yang Shi, Prabhakar Sairam Andhey, Christina Ising, Kairuo Wang, Lisa L Snipes, Jason D Ulrich

Neuron· August 2021

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Neuronal VCP loss of function recapitulates FTLD-TDP pathology.
Abubakar Wani, Jiang Zhu, Jason D Ulrich, Abdallah Eteleeb, Andrew D Sauerbeck

Cell Rep· July 2021

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