Publications by authors named "Jason Hoskins"

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Isoquercetin and Zafirlukast Cooperatively Suppress Tumor Growth and Thromboinflammatory Signaling in a Xenograft Model of Ovarian Cancer.
Justine A Keovilay, Jason W Hoskins, Jean-Pierre Kinet, Thomas C Lines, Daniel R Kennedy

FASEB J· January 2026

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3D chromatin-based variant-to-gene maps across 57 human cell types reveal the cellular and genetic architecture of autoimmune disease susceptibility.
Khanh B Trang, Prabhat Sharma, Laura Cook, Zachary Mount, Rajan M Thomas, Jason W Hoskins

Genome Biol· December 2025

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Large-scale multiomic analysis identifies non-coding somatic driver mutations and nominates as a driver gene for pancreatic ductal adenocarcinoma.
Jun Zhong, Aidan O'Brien, Minal B Patel, Daina Eiser, Michael Mobaraki, Jason W Hoskins

Gut· October 2025

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Predictive prioritization of enhancers associated with pancreatic disease risk.
Li Wang, Songjoon Baek, Gauri Prasad, John Wildenthal, Konnie Guo, Jason W Hoskins

Cell Genom· October 2025

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A Common CTRB misfolding variant associated with pancreatic cancer risk causes ER stress and inflammation in mice.
Cristina Bodas, Irene Felipe, Brice Chanez, Miguel Lafarga, Evangelina Lopez de Maturana, Jason Hoskins

Gut· August 2025

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3D chromatin-based variant-to-gene maps across 57 human cell types reveal the cellular and genetic architecture of autoimmune disease susceptibility.
Khanh B Trang, Prabhat Sharma, Laura Cook, Zachary Mount, Rajan M Thomas, Jason W Hoskins

medRxiv· May 2025

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Allelic effects on KLHL17 expression underlie a pancreatic cancer genome-wide association signal at chr1p36.33.
Katelyn E Connelly, Katherine Hullin, Ehssan Abdolalizadeh, Jun Zhong, Daina Eiser, Jason W Hoskins

Nat Commun· April 2025

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3D genomic features across >50 diverse cell types reveal insights into the genomic architecture of childhood obesity.
Khanh B Trang, Matthew C Pahl, James A Pippin, Chun Su, Sheridan H Littleton, Jason Hoskins

Elife· January 2025

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Predictive Prioritization of Enhancers Associated with Pancreas Disease Risk.
Li Wang, Songjoon Baek, Gauri Prasad, John Wildenthal, Konnie Guo, Jason W Hoskins

bioRxiv· September 2024

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Allelic effects on expression likely mediated by JunB/D underlie a PDAC GWAS signal at chr1p36.33.
Katelyn E Connelly, Katherine Hullin, Ehssan Abdolalizadeh, Jun Zhong, Daina Eiser, Jason W Hoskins

medRxiv· September 2024

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Large-scale multi-omic analysis identifies noncoding somatic driver mutations and nominates as a driver gene for pancreatic ductal adenocarcinoma.
Jun Zhong, Aidan O'Brien, Minal Patel, Daina Eiser, Michael Mobaraki, Jason W Hoskins

medRxiv· September 2024

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3D genomic features across >50 diverse cell types reveal insights into the genomic architecture of childhood obesity.
Khanh B Trang, Matthew C Pahl, James A Pippin, Chun Su, Sheridan H Littleton, Jason W Hoskins

medRxiv· August 2024

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High-throughput characterization of functional variants highlights heterogeneity and polygenicity underlying lung cancer susceptibility.
Erping Long, Harsh Patel, Alyxandra Golden, Michelle Antony, Jinhu Yin, Jason W Hoskins

Am J Hum Genet· July 2024

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A common CTRB misfolding variant associated with pancreatic cancer risk causes ER stress and inflammation in mice.
Cristina Bodas, Irene Felipe, Brice Chanez, Miguel Lafarga, Evangelina López de Maturana, Jason W Hoskins

bioRxiv· July 2024

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Master regulator activity QTL protocol to implicate regulatory pathways potentially mediating GWAS signals using eQTL data.
Jason W Hoskins, Trevor A Christensen, Laufey T Amundadottir

STAR Protoc· September 2023

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Large-Bore Mechanical Thrombectomy of Acute Pulmonary Embolism at a Community-Based Hospital: A Case Series.
Elissa R Ballas, Christopher D Sanders, Jason D Hoskins

Mil Med· August 2023

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Inferred expression regulator activities suggest genes mediating cardiometabolic genetic signals.
Jason W Hoskins, Charles C Chung, Aidan O'Brien, Jun Zhong, Katelyn Connelly

PLoS Comput Biol· November 2021

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A 584 bp deletion in CTRB2 inhibits chymotrypsin B2 activity and secretion and confers risk of pancreatic cancer.
Ashley Jermusyk, Jun Zhong, Katelyn E Connelly, Naomi Gordon, Sumeth Perera, Jason W Hoskins

Am J Hum Genet· October 2021

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A Transcriptome-Wide Association Study Identifies Novel Candidate Susceptibility Genes for Pancreatic Cancer.
Jun Zhong, Ashley Jermusyk, Lang Wu, Jason W Hoskins, Irene Collins

J Natl Cancer Inst· October 2020

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Ultrasound Fatty Liver Indicator: A Simple Tool for Differentiating Steatosis From Nonalcoholic Steatohepatitis: Validity in the Average Obese Population.
Steve M Nelson, Jason D Hoskins, Christopher Lisanti, Jayanta Chaudhuri

J Ultrasound Med· April 2020

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Characterising -regulatory variation in the transcriptome of histologically normal and tumour-derived pancreatic tissues.
Mingfeng Zhang, Soren Lykke-Andersen, Bin Zhu, Wenming Xiao, Jason W Hoskins

Gut· March 2018

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Publisher correction: Functional characterization of a multi-cancer risk locus on chr5p15.33 reveals regulation of TERT by ZNF148.
Jun Fang, Jinping Jia, Matthew Makowski, Mai Xu, Zhaoming Wang, Jason W Hoskins

Nat Commun· March 2018

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Genome-wide meta-analysis identifies five new susceptibility loci for pancreatic cancer.
Alison P Klein, Brian M Wolpin, Harvey A Risch, Rachael Z Stolzenberg-Solomon, Evelina Mocci, Jason W Hoskins

Nat Commun· February 2018

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Functional characterization of a multi-cancer risk locus on chr5p15.33 reveals regulation of TERT by ZNF148.
Jun Fang, Jinping Jia, Matthew Makowski, Mai Xu, Zhaoming Wang, Jason W Hoskins

Nat Commun· May 2017

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Functional characterization of a chr13q22.1 pancreatic cancer risk locus reveals long-range interaction and allele-specific effects on DIS3 expression.
Jason W Hoskins, Abdisamad Ibrahim, Mickey A Emmanuel, Sarah M Manmiller, Yinglun Wu

Hum Mol Genet· November 2016

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