Publications by authors named "Irene Collins"

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Large-scale multiomic analysis identifies non-coding somatic driver mutations and nominates as a driver gene for pancreatic ductal adenocarcinoma.
Jun Zhong, Aidan O'Brien, Minal B Patel, Daina Eiser, Michael Mobaraki, Irene Collins

Gut· October 2025

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Allelic effects on KLHL17 expression underlie a pancreatic cancer genome-wide association signal at chr1p36.33.
Katelyn E Connelly, Katherine Hullin, Ehssan Abdolalizadeh, Jun Zhong, Daina Eiser, Irene Collins

Nat Commun· April 2025

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Allelic effects on expression likely mediated by JunB/D underlie a PDAC GWAS signal at chr1p36.33.
Katelyn E Connelly, Katherine Hullin, Ehssan Abdolalizadeh, Jun Zhong, Daina Eiser, Irene Collins

medRxiv· September 2024

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Large-scale multi-omic analysis identifies noncoding somatic driver mutations and nominates as a driver gene for pancreatic ductal adenocarcinoma.
Jun Zhong, Aidan O'Brien, Minal Patel, Daina Eiser, Michael Mobaraki, Irene Collins

medRxiv· September 2024

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Inferred expression regulator activities suggest genes mediating cardiometabolic genetic signals.
Jason W Hoskins, Charles C Chung, Aidan O'Brien, Jun Zhong, Katelyn Connelly, Irene Collins

PLoS Comput Biol· November 2021

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A 584 bp deletion in CTRB2 inhibits chymotrypsin B2 activity and secretion and confers risk of pancreatic cancer.
Ashley Jermusyk, Jun Zhong, Katelyn E Connelly, Naomi Gordon, Sumeth Perera, Irene Collins

Am J Hum Genet· October 2021

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A Transcriptome-Wide Association Study Identifies Novel Candidate Susceptibility Genes for Pancreatic Cancer.
Jun Zhong, Ashley Jermusyk, Lang Wu, Jason W Hoskins, Irene Collins

J Natl Cancer Inst· October 2020

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Endogenous Gastrin Collaborates With Mutant KRAS in Pancreatic Carcinogenesis.
Sandeep Nadella, Julian Burks, Matthew Huber, Juan Wang, Hong Cao, Irene Collins

Pancreas· August 2019

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Agnostic Pathway/Gene Set Analysis of Genome-Wide Association Data Identifies Associations for Pancreatic Cancer.
Naomi Walsh, Han Zhang, Paula L Hyland, Qi Yang, Evelina Mocci, Irene Collins

J Natl Cancer Inst· June 2019

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Characterising -regulatory variation in the transcriptome of histologically normal and tumour-derived pancreatic tissues.
Mingfeng Zhang, Soren Lykke-Andersen, Bin Zhu, Wenming Xiao, Jason W Hoskins, Irene Collins

Gut· March 2018

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Publisher correction: Functional characterization of a multi-cancer risk locus on chr5p15.33 reveals regulation of TERT by ZNF148.
Jun Fang, Jinping Jia, Matthew Makowski, Mai Xu, Zhaoming Wang, Irene Collins

Nat Commun· March 2018

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Functional characterization of a multi-cancer risk locus on chr5p15.33 reveals regulation of TERT by ZNF148.
Jun Fang, Jinping Jia, Matthew Makowski, Mai Xu, Zhaoming Wang, Irene Collins

Nat Commun· May 2017

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Functional characterization of a chr13q22.1 pancreatic cancer risk locus reveals long-range interaction and allele-specific effects on DIS3 expression.
Jason W Hoskins, Abdisamad Ibrahim, Mickey A Emmanuel, Sarah M Manmiller, Yinglun Wu, Irene Collins

Hum Mol Genet· November 2016

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Three new pancreatic cancer susceptibility signals identified on chromosomes 1q32.1, 5p15.33 and 8q24.21.
Mingfeng Zhang, Zhaoming Wang, Ofure Obazee, Jinping Jia, Erica J Childs, Irene Collins

Oncotarget· October 2016

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Transcriptome analysis of pancreatic cancer reveals a tumor suppressor function for HNF1A.
Jason W Hoskins, Jinping Jia, Marta Flandez, Hemang Parikh, Wenming Xiao, Irene Collins

Carcinogenesis· December 2014

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CLPTM1L promotes growth and enhances aneuploidy in pancreatic cancer cells.
Jinping Jia, Allen D Bosley, Abbey Thompson, Jason W Hoskins, Adam Cheuk, Irene Collins

Cancer Res· May 2014

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An integrated transcriptome and epigenome analysis identifies a novel candidate gene for pancreatic cancer.
Jinping Jia, Hemang Parikh, Wenming Xiao, Jason W Hoskins, Holger Pflicke, Irene Collins

BMC Med Genomics· September 2013

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Fine mapping the KLK3 locus on chromosome 19q13.33 associated with prostate cancer susceptibility and PSA levels.
Hemang Parikh, Zhaoming Wang, Kerry A Pettigrew, Jinping Jia, Sarah Daugherty, Irene Collins

Hum Genet· June 2011

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A comprehensive resequence analysis of the KLK15-KLK3-KLK2 locus on chromosome 19q13.33.
Hemang Parikh, Zuoming Deng, Meredith Yeager, Joseph Boland, Casey Matthews, Irene Collins

Hum Genet· January 2010

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Translating the REACH caregiver intervention for use by area agency on aging personnel: the REACH OUT program.
Louis D Burgio, Irene B Collins, Bettina Schmid, Tracy Wharton, Debra McCallum

Gerontologist· February 2009

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Human promoter genomic composition demonstrates non-random groupings that reflect general cellular function.
Markey C McNutt, Ron Tongbai, Wenwu Cui, Irene Collins, Wendy J Freebern

BMC Bioinformatics· October 2005

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TFIIH operates through an expanded proximal promoter to fine-tune c-myc expression.
Achim Weber, Juhong Liu, Irene Collins, David Levens

Mol Cell Biol· January 2005

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NMR-driven discovery of benzoylanthranilic acid inhibitors of far upstream element binding protein binding to the human oncogene c-myc promoter.
Jeffrey R Huth, Liping Yu, Irene Collins, Jamey Mack, Renaldo Mendoza

J Med Chem· September 2004

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Kinetic profiles of p300 occupancy in vivo predict common features of promoter structure and coactivator recruitment.
James L Smith, Wendy J Freebern, Irene Collins, Adriana De Siervi, Idalia Montano

Proc Natl Acad Sci U S A· August 2004

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Targeting combinatorial transcriptional complex assembly at specific modules within the interleukin-2 promoter by the immunosuppressant SB203580.
James L Smith, Irene Collins, G V R Chandramouli, Wayne G Butscher, Elena Zaitseva

J Biol Chem· October 2003

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