Publications by authors named "Jason LaMar"

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Identification of LY3522348: A Highly Selective and Orally Efficacious Ketohexokinase Inhibitor.
Timothy B Durham, Junliang Hao, Patrick Spinazze, Douglas R Stack, James L Toth, Jason Lamar

J Med Chem· December 2023

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Development of a semi-automated MHC-associated peptide proteomics (MAPPs) method using streptavidin bead-based immunoaffinity capture and nano LC-MS/MS to support immunogenicity risk assessment in drug development.
M Violet Lee, Ola M Saad, Sylvia Wong, Jason LaMar, Lynn Kamen

Front Immunol· December 2023

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Mini-PBPK-Based Population Model and Covariate Analysis to Assess the Complex Pharmacokinetics and Pharmacodynamics of RO7449135, an Anti-KLK5/KLK7 Bispecific Antibody in Cynomolgus Monkeys.
Hao Cai, Xun Tao, Jeongsup Shim, Rebecca N Bauer, Meire Bremer, Jason LaMar

AAPS J· June 2023

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Anthranilic amide and imidazobenzothiadiazole compounds disrupt membrane potential.
Jake Smith, Heather Wescott, Julie Early, Steven Mullen, Junitta Guzman, Jason Lamar

Medchemcomm· June 2019

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Imidazopyridine and Pyrazolopiperidine Derivatives as Novel Inhibitors of Serine Palmitoyl Transferase.
Michael J Genin, Isabel C Gonzalez Valcarcel, William G Holloway, Jason Lamar, Marian Mosior

J Med Chem· June 2016

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Design and synthesis of a novel class of dual PPARgamma/delta agonists.
Isabel C Gonzalez, Jason Lamar, Fatima Iradier, Yanping Xu, Leonard L Winneroski

Bioorg Med Chem Lett· February 2007

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Design and synthesis of dual peroxisome proliferator-activated receptors gamma and delta agonists as novel euglycemic agents with a reduced weight gain profile.
Yanping Xu, Garret J Etgen, Carol L Broderick, Emily Canada, Isabel Gonzalez, Jason Lamar

J Med Chem· September 2006

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P4 and P1' optimization of bicycloproline P2 bearing tetrapeptidyl alpha-ketoamides as HCV protease inhibitors.
Yvonne Yip, Frantz Victor, Jason Lamar, Robert Johnson, Q May Wang

Bioorg Med Chem Lett· October 2004

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P4 cap modified tetrapeptidyl alpha-ketoamides as potent HCV NS3 protease inhibitors.
David X Sun, Lifei Liu, Beverly Heinz, Alexander Kolykhalov, Jason Lamar

Bioorg Med Chem Lett· August 2004

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Phe*-Ala-based pentapeptide mimetics are BACE inhibitors: P2 and P3 SAR.
Jason Lamar, Jingdan Hu, Ana Belen Bueno, Hsiu-Chiung Yang, Deqi Guo

Bioorg Med Chem Lett· January 2004

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P3 cap modified Phe*-Ala series BACE inhibitors.
Shu-Hui Chen, Jason Lamar, Deqi Guo, Todd Kohn, Hsiu-Chiung Yang

Bioorg Med Chem Lett· January 2004

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Discovery of a novel bicycloproline P2 bearing peptidyl alpha-ketoamide LY514962 as HCV protease inhibitor.
Yvonne Yip, Frantz Victor, Jason Lamar, Robert Johnson, Q May Wang

Bioorg Med Chem Lett· January 2004

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P1 and P3 optimization of novel bicycloproline P2 bearing tetrapeptidyl alpha-ketoamide based HCV protease inhibitors.
Frantz Victor, Jason Lamar, Nancy Snyder, Yvonne Yip, Deqi Guo

Bioorg Med Chem Lett· January 2004

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Novel P4 truncated tripeptidyl alpha-ketoamides as HCV protease inhibitors.
Jason Lamar, Frantz Victor, Nancy Snyder, Robert B Johnson, Q May Wang

Bioorg Med Chem Lett· January 2004

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Synthesis and evaluation of tripeptidyl alpha-ketoamides as human rhinovirus 3C protease inhibitors.
Shu-Hui Chen, Jason Lamar, Frantz Victor, Nancy Snyder, Robert Johnson

Bioorg Med Chem Lett· October 2003

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