Publications by authors named "Jason P Gay"

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Nivolumab plus ipilimumab induce hyper-progression in renal medullary carcinoma: results of a phase II trial and preclinical evidence.
Melinda Soeung, Xinmiao Yan, Ciro Zanca, Jing Qian, Menuka Karki, Jason P Gay

Nat Commun· November 2025

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Ether phospholipids are required for mitochondrial reactive oxygen species homeostasis.
Ziheng Chen, I-Lin Ho, Melinda Soeung, Er-Yen Yen, Jintan Liu, Jason P Gay

Nat Commun· April 2023

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Complex I inhibitor of oxidative phosphorylation in advanced solid tumors and acute myeloid leukemia: phase I trials.
Timothy A Yap, Naval Daver, Mikhila Mahendra, Jixiang Zhang, Carlos Kamiya-Matsuoka, Jason P Gay

Nat Med· January 2023

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Feasibility of administering human pancreatic cancer chemotherapy in a spontaneous pancreatic cancer mouse model.
Abagail M Delahoussaye, Joseph Abi Jaoude, Morgan Green, Tara N Fujimoto, Jessica Molkentine, Jason P Gay

BMC Cancer· February 2022

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PRMT1-dependent regulation of RNA metabolism and DNA damage response sustains pancreatic ductal adenocarcinoma.
Virginia Giuliani, Meredith A Miller, Chiu-Yi Liu, Stella R Hartono, Caleb A Class, Jason P Gay

Nat Commun· July 2021

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Discovery of IPN60090, a Clinical Stage Selective Glutaminase-1 (GLS-1) Inhibitor with Excellent Pharmacokinetic and Physicochemical Properties.
Michael J Soth, Kang Le, Maria Emilia Di Francesco, Matthew M Hamilton, Gang Liu, Jason P Gay

J Med Chem· November 2020

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Fatty acid desaturase 1 knockout mice are lean with improved glycemic control and decreased development of atheromatous plaque.
David R Powell, Jason P Gay, Melinda Smith, Nathaniel Wilganowski, Angela Harris

Diabetes Metab Syndr Obes· July 2016

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Design, synthesis, and in vivo activity of novel inhibitors of delta-5 desaturase for the treatment of metabolic syndrome.
Simon D P Baugh, Praveen K Pabba, Joseph Barbosa, Eric Coulter, Urvi Desai, Jason P Gay

Bioorg Med Chem Lett· September 2015

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Diacylglycerol Lipase α Knockout Mice Demonstrate Metabolic and Behavioral Phenotypes Similar to Those of Cannabinoid Receptor 1 Knockout Mice.
David R Powell, Jason P Gay, Nathaniel Wilganowski, Deon Doree, Katerina V Savelieva

Front Endocrinol (Lausanne)· June 2015

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