Publications by authors named "Jay Uhler"

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In Vitro Assays of TWINKLE Function.
Jay P Uhler, Ulrika Alexandersson, Maria Falkenberg

Methods Mol Biol· February 2023

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In Vitro Analysis of mtDNA Replication.
Jay P Uhler, Maria Falkenberg

Methods Mol Biol· March 2021

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Accurate mapping of mitochondrial DNA deletions and duplications using deep sequencing.
Swaraj Basu, Xie Xie, Jay P Uhler, Carola Hedberg-Oldfors, Dusanka Milenkovic

PLoS Genet· December 2020

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Deep sequencing of mitochondrial DNA and characterization of a novel mutation in a patient with arPEO.
Carola Hedberg-Oldfors, Bertil Macao, Swaraj Basu, Christopher Lindberg, Bradley Peter, Jay P Uhler

Neurol Genet· February 2020

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UBTD1 is a mechano-regulator controlling cancer aggressiveness.
Stéphanie Torrino, François-René Roustan, Lisa Kaminski, Thomas Bertero, Sabrina Pisano, Jay P Uhler

EMBO Rep· April 2019

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Copy-choice recombination during mitochondrial L-strand synthesis causes DNA deletions.
Örjan Persson, Yazh Muthukumar, Swaraj Basu, Louise Jenninger, Jay P Uhler

Nat Commun· February 2019

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RNase H1 directs origin-specific initiation of DNA replication in human mitochondria.
Viktor Posse, Ali Al-Behadili, Jay P Uhler, Anders R Clausen, Aurelio Reyes

PLoS Genet· January 2019

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A two-nuclease pathway involving RNase H1 is required for primer removal at human mitochondrial OriL.
Ali Al-Behadili, Jay P Uhler, Anna-Karin Berglund, Bradley Peter, Mara Doimo

Nucleic Acids Res· October 2018

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Identification of a G-quadruplex forming sequence in the promoter of UCP1.
Yuanbo Zhao, Jay P Uhler

Acta Biochim Biophys Sin (Shanghai)· July 2018

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Mice lacking the mitochondrial exonuclease MGME1 accumulate mtDNA deletions without developing progeria.
Stanka Matic, Min Jiang, Thomas J Nicholls, Jay P Uhler, Caren Dirksen-Schwanenland

Nat Commun· March 2018

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MGME1 processes flaps into ligatable nicks in concert with DNA polymerase γ during mtDNA replication.
Jay P Uhler, Christian Thörn, Thomas J Nicholls, Stanka Matic, Dusanka Milenkovic

Nucleic Acids Res· July 2016

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Regulation of DNA replication at the end of the mitochondrial D-loop involves the helicase TWINKLE and a conserved sequence element.
Elisabeth Jemt, Örjan Persson, Yonghong Shi, Majda Mehmedovic, Jay P Uhler

Nucleic Acids Res· October 2015

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Primer removal during mammalian mitochondrial DNA replication.
Jay P Uhler, Maria Falkenberg

DNA Repair (Amst)· October 2015

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The exonuclease activity of DNA polymerase γ is required for ligation during mitochondrial DNA replication.
Bertil Macao, Jay P Uhler, Triinu Siibak, Xuefeng Zhu, Yonghong Shi

Nat Commun· June 2015

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The UbL protein UBTD1 stably interacts with the UBE2D family of E2 ubiquitin conjugating enzymes.
Jay P Uhler, Henrik Spåhr, Géraldine Farge, Stéphan Clavel, Nils-Göran Larsson

Biochem Biophys Res Commun· January 2014

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A hybrid G-quadruplex structure formed between RNA and DNA explains the extraordinary stability of the mitochondrial R-loop.
Paulina H Wanrooij, Jay P Uhler, Yonghong Shi, Fredrik Westerlund, Maria Falkenberg

Nucleic Acids Res· November 2012

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G-quadruplex structures in RNA stimulate mitochondrial transcription termination and primer formation.
Paulina H Wanrooij, Jay P Uhler, Tomas Simonsson, Maria Falkenberg, Claes M Gustafsson

Proc Natl Acad Sci U S A· September 2010

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The Drosophila Nkx6 homeodomain protein has both activation and repression domains and can activate target gene expression.
Li-Jyun Syu, Jay Uhler, Huanqing Zhang, Dervla M Mellerick

Brain Res· April 2009

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Reversal of RNA polymerase II ubiquitylation by the ubiquitin protease Ubp3.
Kristian Kvint, Jay P Uhler, Michael J Taschner, Stefan Sigurdsson, Hediye Erdjument-Bromage

Mol Cell· May 2008

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A role for noncoding transcription in activation of the yeast PHO5 gene.
Jay P Uhler, Christina Hertel, Jesper Q Svejstrup

Proc Natl Acad Sci U S A· May 2007

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The Nk-2 box of the Drosophila homeodomain protein, Vnd, contributes to its repression activity in a Groucho-dependent manner.
Jay Uhler, Huanqing Zhang, Li-Jyun Syu, Dervla M Mellerick

Mech Dev· January 2007

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Nk6, a novel Drosophila homeobox gene regulated by vnd.
Jay Uhler, James Garbern, Li Yang, John Kamholz, Dervla M Mellerick

Mech Dev· August 2002

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