Publications by authors named "Jay Wendling"

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Nucleotide P2Y receptor agonists are in vitro and in vivo prodrugs of A/A adenosine receptor agonists: implications for roles of P2Y and A/A receptors in physiology and pathology.
Theodore E Liston, Sonja Hinz, Christa E Müller, Deborah M Holstein, Jay Wendling

Purinergic Signal· December 2020

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Corrigendum: Sterol metabolism controls TH17 differentiation by generating endogenous RORγ agonists.
Xiao Hu, Yahong Wang, Ling-Yang Hao, Xikui Liu, Chuck A Lesch, Jay M Wendling

Nat Chem Biol· September 2015

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Sterol metabolism controls T(H)17 differentiation by generating endogenous RORγ agonists.
Xiao Hu, Yahong Wang, Ling-Yang Hao, Xikui Liu, Chuck A Lesch, Jay M Wendling

Nat Chem Biol· February 2015

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Modulation of cellular S1P levels with a novel, potent and specific inhibitor of sphingosine kinase-1.
Mark E Schnute, Matthew D McReynolds, Tom Kasten, Matthew Yates, Gina Jerome, Jay Wendling

Biochem J· May 2012

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Structure-based parallel medicinal chemistry approach to improve metabolic stability of benzopyran COX-2 inhibitors.
Li Xing, Bruce C Hamper, Theresa R Fletcher, Jay M Wendling, Jeffery Carter

Bioorg Med Chem Lett· February 2011

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Discovery of (3S,3aR)-2-(3-chloro-4-cyanophenyl)-3-cyclopentyl-3,3a,4,5-tetrahydro-2H-benzo[g]indazole-7-carboxylic acid (PF-3882845), an orally efficacious mineralocorticoid receptor (MR) antagonist for hypertension and nephropathy.
Marvin J Meyers, Graciela B Arhancet, Susan L Hockerman, Xiangyang Chen, Scott A Long, Jay M Wendling

J Med Chem· August 2010

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A novel autotaxin inhibitor reduces lysophosphatidic acid levels in plasma and the site of inflammation.
James Gierse, Atli Thorarensen, Konstantine Beltey, Erica Bradshaw-Pierce, Luz Cortes-Burgos, Jay Wendling

J Pharmacol Exp Ther· July 2010

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Biochemical, cellular, and anti-inflammatory properties of a potent, selective, orally bioavailable benzamide inhibitor of Rho kinase activity.
Lakshman E Rajagopalan, Michael S Davies, Larry E Kahn, Christine M Kornmeier, Hideaki Shimada, Jay M Wendling

J Pharmacol Exp Ther· June 2010

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