Publications by authors named "Ling-Yang Hao"

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Transcriptomic profiling of Sjögren's disease salivary glands identifies signatures associated with both follicular and extrafollicular responses linked to rheumatoid factor and anti-La/SSB seropositivity.
Elena Pontarini, Davide Lucchesi, Elisabetta Sciacca, Giulia Cavallaro, Qingxuan Song, Ling-Yang Hao

Ann Rheum Dis· November 2025

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A randomized, double-blind, placebo-controlled, single- and multiple-dose phase 1 study of VE202, a defined bacterial consortium for treatment of inflammatory bowel disease: safety and colonization dynamics of a novel live biotherapeutic product in healthy adults.
Jeffrey L Silber, Jason M Norman, Tokuwa Kanno, Emily M Crossette, Rose Szabady, Ling-Yang Hao

Eur J Gastroenterol Hepatol· October 2025

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Publisher Correction: Interferon subverts an AHR-JUN axis to promote CXCL13 T cells in lupus.
Calvin Law, Vanessa Sue Wacleche, Ye Cao, Arundhati Pillai, John Sowerby, Ling-Yang Hao

Nature· August 2024

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Interferon subverts an AHR-JUN axis to promote CXCL13 T cells in lupus.
Calvin Law, Vanessa Sue Wacleche, Ye Cao, Arundhati Pillai, John Sowerby, Ling-Yang Hao

Nature· July 2024

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Transcriptomic profiling of programmed cell death 1 (PD-1) expressing T cells in early rheumatoid arthritis identifies a decreased CD4 + PD-1 + signature post-treatment.
Katie Lowe, Annabelle Small, Qingxuan Song, Ling-Yang Hao, William Murray-Brown

Sci Rep· February 2023

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Differential expansion of T peripheral helper cells in early rheumatoid arthritis and osteoarthritis synovium.
William Murray-Brown, Yanxia Guo, Annabelle Small, Katie Lowe, Helen Weedon, Ling-Yang Hao

RMD Open· October 2022

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Distinct stromal and immune cell interactions shape the pathogenesis of rheumatoid and psoriatic arthritis.
Achilleas Floudas, Conor M Smith, Orla Tynan, Nuno Neto, Vinod Krishna, Ling-Yang Hao

Ann Rheum Dis· August 2022

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Attenuation of the BTLA/HVEM Regulatory Network in the Circulation in Primary Sjögren's Syndrome.
Annabelle Small, Suzanne Cole, Jing J Wang, Sunil Nagpal, Ling-Yang Hao

J Clin Med· January 2022

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Discovery of LYC-55716: A Potent, Selective, and Orally Bioavailable Retinoic Acid Receptor-Related Orphan Receptor-γ (RORγ) Agonist for Use in Treating Cancer.
Thomas D Aicher, Chad A Van Huis, Alexander R Hurd, Donald J Skalitzky, Clarke B Taylor, Ling-Yang Hao

J Med Chem· September 2021

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Inhibiting Oxidative Phosphorylation In Vivo Restrains Th17 Effector Responses and Ameliorates Murine Colitis.
Luigi Franchi, Ivan Monteleone, Ling-Yang Hao, Mark A Spahr, Wenpu Zhao

J Immunol· April 2017

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Corrigendum: Sterol metabolism controls TH17 differentiation by generating endogenous RORγ agonists.
Xiao Hu, Yahong Wang, Ling-Yang Hao, Xikui Liu, Chuck A Lesch

Nat Chem Biol· September 2015

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Programmed death-1 controls T cell survival by regulating oxidative metabolism.
Victor Tkachev, Stefanie Goodell, Anthony W Opipari, Ling-Yang Hao, Luigi Franchi

J Immunol· June 2015

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Sterol metabolism controls T(H)17 differentiation by generating endogenous RORγ agonists.
Xiao Hu, Yahong Wang, Ling-Yang Hao, Xikui Liu, Chuck A Lesch

Nat Chem Biol· February 2015

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Anaplerotic metabolism of alloreactive T cells provides a metabolic approach to treat graft-versus-host disease.
Gary D Glick, Rodrigue Rossignol, Costas A Lyssiotis, Daniel Wahl, Charles Lesch, Ling-Yang Hao

J Pharmacol Exp Ther· November 2014

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Inflammasomes in inflammatory bowel disease pathogenesis.
Ling-Yang Hao, Xikui Liu, Luigi Franchi

Curr Opin Gastroenterol· July 2013

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DJ-1 is critical for mitochondrial function and rescues PINK1 loss of function.
Ling-Yang Hao, Benoit I Giasson, Nancy M Bonini

Proc Natl Acad Sci U S A· May 2010

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RNA binding activity of the recessive parkinsonism protein DJ-1 supports involvement in multiple cellular pathways.
Marcel P van der Brug, Jeff Blackinton, Jayanth Chandran, Ling-Yang Hao, Ashish Lal

Proc Natl Acad Sci U S A· July 2008

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Short telomeres, even in the presence of telomerase, limit tissue renewal capacity.
Ling-Yang Hao, Mary Armanios, Margaret A Strong, Baktiar Karim, David M Feldser

Cell· December 2005

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Phosphorylation of H2AX at short telomeres in T cells and fibroblasts.
Ling-Yang Hao, Margaret A Strong, Carol W Greider

J Biol Chem· October 2004

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Genomic instability in both wild-type and telomerase null MEFs.
Ling-Yang Hao, Carol W Greider

Chromosoma· September 2004

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Insulin-like growth factor-II induces hypertrophy of adult cardiomyocytes via two alternative pathways.
Chih-Yang Huang, Ling-Yang Hao, Dennis E Buetow

Cell Biol Int· February 2003

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Hypertrophy of cultured adult rat ventricular cardiomyocytes induced by antibodies against the insulin-like growth factor (IGF)-I or the IGF-I receptor is IGF-II-dependent.
Chih-Yang Huang, Ling-Yang Hao, Dennis E Buetow

Mol Cell Biochem· April 2002

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Insulin-like growth factor-induced hypertrophy of cultured adult rat cardiomyocytes is L-type calcium-channel-dependent.
Chih-Yang Huang, Ling-Yang Hao, Dennis E Buetow

Mol Cell Biochem· February 2002

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