Publications by authors named "Jean Leif"

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Prevention of type 1 diabetes in the rat with an allele-specific anti-T-cell receptor antibody: Vβ13 as a therapeutic target and biomarker.
Zhijun Liu, Laura Cort, Ryan Eberwine, Thomas Herrmann, Jean H Leif

Diabetes· May 2012

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Engraftment of human HSCs in nonirradiated newborn NOD-scid IL2rγ null mice is enhanced by transgenic expression of membrane-bound human SCF.
Michael A Brehm, Waldemar J Racki, Jean Leif, Lisa Burzenski, Vishnu Hosur

Blood· March 2012

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Targeted disruption of the CCR5 gene in human hematopoietic stem cells stimulated by peptide nucleic acids.
Erica B Schleifman, Ranjit Bindra, Jean Leif, Jacob del Campo, Faye A Rogers

Chem Biol· September 2011

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Human islet cell MORF/cMORF pretargeting in a xenogeneic murine transplant model.
Guozheng Liu, Shuping Dou, Dengfeng Cheng, Jean Leif, Mary Rusckowski

Mol Pharm· June 2011

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Leptin treatment confers clinical benefit at multiple stages of virally induced type 1 diabetes in BB rats.
Annie J Kruger, Chaoxing Yang, Kathryn L Lipson, Stephen C Pino, Jean H Leif

Autoimmunity· March 2011

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Human immune system development and rejection of human islet allografts in spontaneously diabetic NOD-Rag1null IL2rgammanull Ins2Akita mice.
Michael A Brehm, Rita Bortell, Philip Diiorio, Jean Leif, Joseph Laning

Diabetes· September 2010

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Infection with viruses from several families triggers autoimmune diabetes in LEW*1WR1 rats: prevention of diabetes by maternal immunization.
Rebecca S Tirabassi, Dennis L Guberski, Elizabeth P Blankenhorn, Jean H Leif, Bruce A Woda

Diabetes· January 2010

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Analysis of the rat Iddm14 diabetes susceptibility locus in multiple rat strains: identification of a susceptibility haplotype in the Tcrb-V locus.
John P Mordes, Laura Cort, Elaine Norowski, Jean Leif, Jessica M Fuller

Mamm Genome· March 2009

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A new Hu-PBL model for the study of human islet alloreactivity based on NOD-scid mice bearing a targeted mutation in the IL-2 receptor gamma chain gene.
Marie King, Todd Pearson, Leonard D Shultz, Jean Leif, Rita Bottino

Clin Immunol· March 2008

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Development of new-generation HU-PBMC-NOD/SCID mice to study human islet alloreactivity.
Marie King, Todd Pearson, Leonard D Shultz, Jean Leif, Rita Bottino

Ann N Y Acad Sci· April 2007

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Refinement of the Iddm4 diabetes susceptibility locus reveals TCRVbeta4 as a candidate gene.
Elizabeth P Blankenhorn, Cheryl Descipio, Lucy Rodemich, Laura Cort, Jean H Leif

Ann N Y Acad Sci· April 2007

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A regulatory CD4+ T cell subset in the BB rat model of autoimmune diabetes expresses neither CD25 nor Foxp3.
Jan-Luuk Hillebrands, Barbara Whalen, Jeroen T J Visser, Jasper Koning, Kenneth D Bishop, Jean Leif

J Immunol· December 2006

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Anti-mouse CD154 antibody treatment facilitates generation of mixed xenogeneic rat hematopoietic chimerism, prevents wasting disease and prolongs xenograft survival in mice.
Hideyuki Masaki, Michael C Appel, Linda Leahy, Jean Leif, Linda Paquin

Xenotransplantation· May 2006

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LEW.1WR1 rats develop autoimmune diabetes spontaneously and in response to environmental perturbation.
John P Mordes, Dennis L Guberski, Jean H Leif, Bruce A Woda, Joan F Flanagan

Diabetes· September 2005

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The rat diabetes susceptibility locus Iddm4 and at least one additional gene are required for autoimmune diabetes induced by viral infection.
Elizabeth P Blankenhorn, Lucy Rodemich, Cristina Martin-Fernandez, Jean Leif, Dale L Greiner

Diabetes· April 2005

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Evaluation of donor-specific transfusion sources: unique failure of bone marrow cells to induce prolonged skin allograft survival with anti-CD154 monoclonal antibody.
Thomas G Markees, Todd Pearson, Amy Cuthbert, Andrea L Pearson, Leonard D Shultz, Jean Leif

Transplantation· December 2004

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Regulation of skin and islet allograft survival in mice treated with costimulation blockade is mediated by different CD4+ cell subsets and different mechanisms.
Scott J Banuelos, Thomas G Markees, Nancy E Phillips, Michael C Appel, Amy Cuthbert, Jean Leif

Transplantation· September 2004

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Comparative mapping of rat Iddm4 to segments on HSA7 and MMU6.
Lars Hornum, Cheryl DeScipio, Helle Markholst, Scott A Troutman, Stephen Novak, Jean Leif

Mamm Genome· January 2004

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NOD/LtSz-Rag1nullPfpnull mice: a new model system with increased levels of human peripheral leukocyte and hematopoietic stem-cell engraftment.
Leonard D Shultz, Scott Banuelos, Bonnie Lyons, Rebecca Samuels, Lisa Burzenski, Jean Leif

Transplantation· October 2003

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Regulation of human short-term repopulating cell (STRC) engraftment in NOD/SCID mice by host CD122+ cells.
Leonard D Shultz, Scott J Banuelos, Jean Leif, Michael C Appel, Melody Cunningham

Exp Hematol· June 2003

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The iddm4 locus segregates with diabetes susceptibility in congenic WF.iddm4 rats.
John P Mordes, Jean Leif, Stephen Novak, Cheryl DeScipio, Dale L Greiner

Diabetes· November 2002

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T cell developmental defects in 'viable motheaten' mice deficient in SHP-1 protein-tyrosine phosphatase. Developmental defects are corrected in vitro in the presence of normal hematopoietic-origin stromal cells and in vivo by exogenous IL-7.
Sherri W Christianson, Dale L Greiner, Dominick Deluca, Jean Leif, Nancy E Phillips

J Autoimmun· March 2002

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