Publications by authors named "Jennifer R Gamble"

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Endo-chip laser-induced thrombus formation: a vessel-on-chip model for in vitro testing of antithrombotic agents.
Alexander Dupuy, Miao Qi, Jemma C L Fenwick, Daisie M Yates, Paul R Coleman, Jennifer R Gamble

Blood Vessel Thromb Hemost· November 2025

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P selectin promotes SARS-CoV-2 interactions with platelets and the endothelium.
Cesar L Moreno, Fernanda Vs Castanheira, Alberto Ospina Stella, Felicity Chung, Anupriya Aggarwal, Jennifer R Gamble

J Clin Invest· November 2025

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The Role of the MiR-181 Family in Hepatocellular Carcinoma.
Jinbiao Chen, Ken Liu, Mathew A Vadas, Jennifer R Gamble, Geoffrey W McCaughan

Cells· July 2024

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Targeting the SphK1/S1P/PFKFB3 axis suppresses hepatocellular carcinoma progression by disrupting glycolytic energy supply that drives tumor angiogenesis.
Xin Tracy Liu, Yu Huang, Da Liu, Yingxin Celia Jiang, Min Zhao, Jennifer Ruth Gamble

J Transl Med· January 2024

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Vascular senescence and leak are features of the early breakdown of the blood-brain barrier in Alzheimer's disease models.
Ka Ka Ting, Paul Coleman, Hani Jieun Kim, Yang Zhao, Jocelyne Mulangala, Jennifer R Gamble

Geroscience· December 2023

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Novel miRNA-based drug CD5-2 reduces liver tumor growth in diethylnitrosamine-treated mice by normalizing tumor vasculature and altering immune infiltrate.
Ken Liu, Jinbiao Chen, Yang Zhao, Jade Boland, Ka Ka Ting, Jennifer R Gamble

Front Immunol· October 2023

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Vessels that encapsulate tumour clusters vascular pattern in hepatocellular carcinoma.
Ken Liu, Claude Dennis, David S Prince, Felix Marsh-Wakefield, Cositha Santhakumar, Jennifer R Gamble

JHEP Rep· August 2023

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Liver-specific deletion of miR-181ab1 reduces liver tumour progression via upregulation of CBX7.
Jinbiao Chen, Yang Zhao, Fan Zhang, Jia Li, Jade A Boland, Jennifer R Gamble

Cell Mol Life Sci· July 2022

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Development of Novel Therapeutics Targeting the Blood-Brain Barrier: From Barrier to Carrier.
Jia Li, Meng Zheng, Olga Shimoni, William A Banks, Ashley I Bush, Jennifer R Gamble

Adv Sci (Weinh)· August 2021

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Machine learning workflows identify a microRNA signature of insulin transcription in human tissues.
Wilson K M Wong, Mugdha V Joglekar, Vijit Saini, Guozhi Jiang, Charlotte X Dong, Jennifer R Gamble

iScience· April 2021

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The VE-Cadherin/β-catenin signalling axis regulates immune cell infiltration into tumours.
Yang Zhao, Jia Li, Ka Ka Ting, Jinbiao Chen, Paul Coleman, Jennifer R Gamble

Cancer Lett· January 2021

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The aging endothelium.
Ka Ka Ting, Paul Coleman, Yang Zhao, Mathew A Vadas, Jennifer R Gamble

Vasc Biol· January 2021

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Regulation of hepatic insulin signaling and glucose homeostasis by sphingosine kinase 2.
Gulibositan Aji, Yu Huang, Mei Li Ng, Wei Wang, Tian Lan, Jennifer R Gamble

Proc Natl Acad Sci U S A· September 2020

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Targeting miR-27a/VE-cadherin interactions rescues cerebral cavernous malformations in mice.
Jia Li, Yang Zhao, Jaesung Choi, Ka Ka Ting, Paul Coleman, Jennifer R Gamble

PLoS Biol· June 2020

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YAP and the RhoC regulator ARHGAP18, are required to mediate flow-dependent endothelial cell alignment.
Paul R Coleman, Angelina J Lay, Ka Ka Ting, Yang Zhao, Jia Li, Jennifer R Gamble

Cell Commun Signal· February 2020

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Low fluid shear stress conditions contribute to activation of cerebral cavernous malformation signalling pathways.
Jia Li, Yang Zhao, Paul Coleman, Jinbiao Chen, Ka Ka Ting, Jennifer R Gamble

Biochim Biophys Acta Mol Basis Dis· November 2019

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Therapeutic regulation of VE-cadherin with a novel oligonucleotide drug for diabetic eye complications using retinopathy mouse models.
Ka Ka Ting, Yang Zhao, Weiyong Shen, Paul Coleman, Michelle Yam, Jennifer R Gamble

Diabetologia· February 2019

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ARHGAP18: A Flow-Responsive Gene That Regulates Endothelial Cell Alignment and Protects Against Atherosclerosis.
Angelina J Lay, Paul R Coleman, Ann Formaz-Preston, Ka Ka Ting, Ben Roediger, Jennifer R Gamble

J Am Heart Assoc· January 2019

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Deletion of sphingosine kinase 1 inhibits liver tumorigenesis in diethylnitrosamine-treated mice.
Jinbiao Chen, Yanfei Qi, Yang Zhao, Dominik Kaczorowski, Timothy A Couttas, Jennifer R Gamble

Oncotarget· March 2018

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Targeting Vascular Endothelial-Cadherin in Tumor-Associated Blood Vessels Promotes T-cell-Mediated Immunotherapy.
Yang Zhao, Ka Ka Ting, Jia Li, Victoria C Cogger, Jinbiao Chen, Jennifer R Gamble

Cancer Res· August 2017

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ARHGAP18 Protects Against Thoracic Aortic Aneurysm Formation by Mitigating the Synthetic and Proinflammatory Smooth Muscle Cell Phenotype.
Renjing Liu, Lisa Lo, Angelina J Lay, Yang Zhao, Ka Ka Ting, Jennifer R Gamble

Circ Res· August 2017

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Targeting the vasculature in hepatocellular carcinoma treatment: Starving versus normalizing blood supply.
Ken Liu, Xiang Zhang, Weiqi Xu, Jinbiao Chen, Jun Yu, Jennifer R Gamble

Clin Transl Gastroenterol· June 2017

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The RhoGAP protein ARHGAP18/SENEX localizes to microtubules and regulates their stability in endothelial cells.
Michael D Lovelace, Elizabeth E Powter, Paul R Coleman, Yang Zhao, Amelia Parker, Jennifer R Gamble

Mol Biol Cell· April 2017

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Ionizing radiation reduces ADAM10 expression in brain microvascular endothelial cells undergoing stress-induced senescence.
Lucinda S McRobb, Matthew J McKay, Jennifer R Gamble, Michael Grace, Vaughan Moutrie

Aging (Albany NY)· April 2017

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The Poly-cistronic miR-23-27-24 Complexes Target Endothelial Cell Junctions: Differential Functional and Molecular Effects of miR-23a and miR-23b.
Jia Li, Yang Zhao, Ying Lu, William Ritchie, Georges Grau, Jennifer R Gamble

Mol Ther Nucleic Acids· August 2016

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