Publications by authors named "Mathew A Vadas"

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The Role of the MiR-181 Family in Hepatocellular Carcinoma.
Jinbiao Chen, Ken Liu, Mathew A Vadas, Jennifer R Gamble, Geoffrey W McCaughan

Cells· July 2024

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Targeting the SphK1/S1P/PFKFB3 axis suppresses hepatocellular carcinoma progression by disrupting glycolytic energy supply that drives tumor angiogenesis.
Xin Tracy Liu, Yu Huang, Da Liu, Yingxin Celia Jiang, Min Zhao, Mathew Alexander Vadas

J Transl Med· January 2024

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Vascular senescence and leak are features of the early breakdown of the blood-brain barrier in Alzheimer's disease models.
Ka Ka Ting, Paul Coleman, Hani Jieun Kim, Yang Zhao, Jocelyne Mulangala, Mathew A Vadas

Geroscience· December 2023

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Novel miRNA-based drug CD5-2 reduces liver tumor growth in diethylnitrosamine-treated mice by normalizing tumor vasculature and altering immune infiltrate.
Ken Liu, Jinbiao Chen, Yang Zhao, Jade Boland, Ka Ka Ting, Mathew A Vadas

Front Immunol· October 2023

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Liver-specific deletion of miR-181ab1 reduces liver tumour progression via upregulation of CBX7.
Jinbiao Chen, Yang Zhao, Fan Zhang, Jia Li, Jade A Boland, Mathew A Vadas

Cell Mol Life Sci· July 2022

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Identification of circulating sphingosine kinase-related metabolites for prediction of type 2 diabetes.
Qi Chen, Wei Wang, Ming-Feng Xia, You-Li Lu, Hua Bian, Mathew A Vadas

J Transl Med· September 2021

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The VE-Cadherin/β-catenin signalling axis regulates immune cell infiltration into tumours.
Yang Zhao, Jia Li, Ka Ka Ting, Jinbiao Chen, Paul Coleman, Mathew A Vadas

Cancer Lett· January 2021

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The aging endothelium.
Ka Ka Ting, Paul Coleman, Yang Zhao, Mathew A Vadas, Jennifer R Gamble

Vasc Biol· January 2021

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Regulation of hepatic insulin signaling and glucose homeostasis by sphingosine kinase 2.
Gulibositan Aji, Yu Huang, Mei Li Ng, Wei Wang, Tian Lan, Mathew A Vadas

Proc Natl Acad Sci U S A· September 2020

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Targeting miR-27a/VE-cadherin interactions rescues cerebral cavernous malformations in mice.
Jia Li, Yang Zhao, Jaesung Choi, Ka Ka Ting, Paul Coleman, Mathew A Vadas

PLoS Biol· June 2020

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YAP and the RhoC regulator ARHGAP18, are required to mediate flow-dependent endothelial cell alignment.
Paul R Coleman, Angelina J Lay, Ka Ka Ting, Yang Zhao, Jia Li, Mathew A Vadas

Cell Commun Signal· February 2020

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Low fluid shear stress conditions contribute to activation of cerebral cavernous malformation signalling pathways.
Jia Li, Yang Zhao, Paul Coleman, Jinbiao Chen, Ka Ka Ting, Mathew A Vadas

Biochim Biophys Acta Mol Basis Dis· November 2019

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Therapeutic regulation of VE-cadherin with a novel oligonucleotide drug for diabetic eye complications using retinopathy mouse models.
Ka Ka Ting, Yang Zhao, Weiyong Shen, Paul Coleman, Michelle Yam, Mathew A Vadas

Diabetologia· February 2019

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ARHGAP18: A Flow-Responsive Gene That Regulates Endothelial Cell Alignment and Protects Against Atherosclerosis.
Angelina J Lay, Paul R Coleman, Ann Formaz-Preston, Ka Ka Ting, Ben Roediger, Mathew A Vadas

J Am Heart Assoc· January 2019

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Deletion of sphingosine kinase 1 inhibits liver tumorigenesis in diethylnitrosamine-treated mice.
Jinbiao Chen, Yanfei Qi, Yang Zhao, Dominik Kaczorowski, Timothy A Couttas, Mathew A Vadas

Oncotarget· March 2018

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Targeting Vascular Endothelial-Cadherin in Tumor-Associated Blood Vessels Promotes T-cell-Mediated Immunotherapy.
Yang Zhao, Ka Ka Ting, Jia Li, Victoria C Cogger, Jinbiao Chen, Mathew A Vadas

Cancer Res· August 2017

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ARHGAP18 Protects Against Thoracic Aortic Aneurysm Formation by Mitigating the Synthetic and Proinflammatory Smooth Muscle Cell Phenotype.
Renjing Liu, Lisa Lo, Angelina J Lay, Yang Zhao, Ka Ka Ting, Mathew A Vadas

Circ Res· August 2017

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The RhoGAP protein ARHGAP18/SENEX localizes to microtubules and regulates their stability in endothelial cells.
Michael D Lovelace, Elizabeth E Powter, Paul R Coleman, Yang Zhao, Amelia Parker, Mathew A Vadas

Mol Biol Cell· April 2017

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The Poly-cistronic miR-23-27-24 Complexes Target Endothelial Cell Junctions: Differential Functional and Molecular Effects of miR-23a and miR-23b.
Jia Li, Yang Zhao, Ying Lu, William Ritchie, Georges Grau, Mathew A Vadas

Mol Ther Nucleic Acids· August 2016

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Deletion of sphingosine kinase 1 ameliorates hepatic steatosis in diet-induced obese mice: Role of PPARγ.
Jinbiao Chen, Wei Wang, Yanfei Qi, Dominik Kaczorowski, Geoffrey W McCaughan, Mathew A Vadas

Biochim Biophys Acta· February 2016

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ARHGAP18: an endogenous inhibitor of angiogenesis, limiting tip formation and stabilizing junctions.
Garry H K Chang, Angelina J Lay, Ka Ka Ting, Yang Zhao, Paul R Coleman, Mathew A Vadas

Small GTPases· July 2015

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Caveolae control the anti-inflammatory phenotype of senescent endothelial cells.
Elizabeth E Powter, Paul R Coleman, Mai H Tran, Angelina J Lay, Patrick Bertolino, Mathew A Vadas

Aging Cell· February 2015

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Beyond liver fibrosis: hepatic stellate cell senescence links obesity to liver cancer by way of the microbiome.
Nicholas A Shackel, Mathew A Vadas, Jennifer R Gamble, Geoffrey W McCaughan

Hepatology· June 2014

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Age-associated stresses induce an anti-inflammatory senescent phenotype in endothelial cells.
Paul R Coleman, Garry Chang, Gabor Hutas, Matthew Grimshaw, Mathew A Vadas

Aging (Albany NY)· December 2013

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Regulation of vascular leak and recovery from ischemic injury by general and VE-cadherin-restricted miRNA antagonists of miR-27.
Jennifer A Young, Ka Ka Ting, Jia Li, Thorleif Moller, Louise Dunn, Mathew A Vadas

Blood· October 2013

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