Publications by authors named "Jennifer Rocnik"

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Small molecule targeting of chromatin writers in cancer.
Andrew R Conery, Jennifer L Rocnik, Patrick Trojer

Nat Chem Biol· February 2022

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Discovery of Selective, Covalent FGFR4 Inhibitors with Antitumor Activity in Models of Hepatocellular Carcinoma.
Haibo Liu, Deqiang Niu, Robert Tjin Tham Sjin, Alex Dubrovskiy, Zhendong Zhu, Jennifer Rocnik

ACS Med Chem Lett· October 2020

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Inhibition of Acetyl-CoA Carboxylase by Phosphorylation or the Inhibitor ND-654 Suppresses Lipogenesis and Hepatocellular Carcinoma.
James S V Lally, Sarani Ghoshal, Danielle K DePeralta, Omeed Moaven, Lan Wei, Jennifer L Rocnik

Cell Metab· January 2019

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Anti-leukaemic activity of the TYK2 selective inhibitor NDI-031301 in T-cell acute lymphoblastic leukaemia.
Koshi Akahane, Zhaodong Li, Julia Etchin, Alla Berezovskaya, Evisa Gjini, Jennifer Rocnik

Br J Haematol· April 2017

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Lead optimization attrition analysis (LOAA): a novel and general methodology for medicinal chemistry.
Mark Munson, Harvey Lieberman, Elina Tserlin, Jennifer Rocnik, Jie Ge

Drug Discov Today· August 2015

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Anti-miR-21 Suppresses Hepatocellular Carcinoma Growth via Broad Transcriptional Network Deregulation.
Timothy R Wagenaar, Sonya Zabludoff, Sung-Min Ahn, Charles Allerson, Heike Arlt, Jennifer L Rocnik

Mol Cancer Res· June 2015

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PIM inhibitors target CD25-positive AML cells through concomitant suppression of STAT5 activation and degradation of MYC oncogene.
Zhuyan Guo, Anlai Wang, Weidong Zhang, Mikhail Levit, Qiang Gao, Jennifer Rocnik

Blood· September 2014

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Evaluation of cancer dependence and druggability of PRP4 kinase using cellular, biochemical, and structural approaches.
Qiang Gao, Ingrid Mechin, Nayantara Kothari, Zhuyan Guo, Gejing Deng, Jennifer Rocnik

J Biol Chem· October 2013

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FLT3-ITD up-regulates MCL-1 to promote survival of stem cells in acute myeloid leukemia via FLT3-ITD-specific STAT5 activation.
Goichi Yoshimoto, Toshihiro Miyamoto, Siamak Jabbarzadeh-Tabrizi, Tadafumi Iino, Jennifer L Rocnik

Blood· December 2009

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Kinase activation and transformation by NUP214-ABL1 is dependent on the context of the nuclear pore.
Kim De Keersmaecker, Jennifer L Rocnik, Rafael Bernad, Benjamin H Lee, Dena Leeman

Mol Cell· July 2008

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Structural and numerical variation of FLT3/ITD in pediatric AML.
Soheil Meshinchi, Derek L Stirewalt, Todd A Alonzo, Titus J Boggon, Robert B Gerbing, Jennifer L Rocnik

Blood· May 2008

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Roles of tyrosine 589 and 591 in STAT5 activation and transformation mediated by FLT3-ITD.
Jennifer L Rocnik, Rachel Okabe, Jin-Chen Yu, Benjamin H Lee, Neill Giese

Blood· August 2006

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Cell-autonomous and -nonautonomous contributions of STAT1 in murine models of tumorigenesis.
Jennifer L Rocnik, D Gary Gilliland

Cancer Cell· July 2006

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