Publications by authors named "Jeremy Baker"

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Tau-RNA complexes inhibit microtubule polymerization and drive disease-relevant conformation change.
Pamela J McMillan, Sarah J Benbow, Rikki Uhrich, Aleen Saxton, Misa Baum, Jeremy Baker

Brain· August 2023

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Correction to: Hsp90 co‑chaperones, FKBP52 and Aha1, promote tau pathogenesis in aged wild‑type mice.
Marangelie Criado-Marrero, Niat T Gebru, Danielle M Blazier, Lauren A Gould, Jeremy D Baker

Acta Neuropathol Commun· May 2021

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Hsp90 co-chaperones, FKBP52 and Aha1, promote tau pathogenesis in aged wild-type mice.
Marangelie Criado-Marrero, Niat T Gebru, Danielle M Blazier, Lauren A Gould, Jeremy D Baker

Acta Neuropathol Commun· April 2021

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AlphaScreen Identifies MSUT2 Inhibitors for Tauopathy-Targeting Therapeutic Discovery.
Jeremy D Baker, Rikki L Uhrich, Timothy J Strovas, Aleen D Saxton, Brian C Kraemer

SLAS Discov· March 2021

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A drug repurposing screen identifies hepatitis C antivirals as inhibitors of the SARS-CoV2 main protease.
Jeremy D Baker, Rikki L Uhrich, Gerald C Kraemer, Jason E Love, Brian C Kraemer

PLoS One· February 2021

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Aberrant AZIN2 and polyamine metabolism precipitates tau neuropathology.
Leslie A Sandusky-Beltran, Andrii Kovalenko, Devon S Placides, Kevin Ratnasamy, Chao Ma, Jeremy D Baker

J Clin Invest· February 2021

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Catalysis of proline isomerization and molecular chaperone activity in a tug-of-war.
Filippo Favretto, David Flores, Jeremy D Baker, Timo Strohäker, Loren B Andreas

Nat Commun· November 2020

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Targeting Pathological Tau by Small Molecule Inhibition of the Poly(A):MSUT2 RNA-Protein Interaction.
Jeremy D Baker, Rikki L Uhrich, Timothy J Strovas, Aleen D Saxton, Brian C Kraemer

ACS Chem Neurosci· August 2020

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On the establishment of a mutant.
Jeremy Baker, Pavel Chigansky, Peter Jagers, Fima C Klebaner

J Math Biol· May 2020

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The Molecular Basis of the Interaction of Cyclophilin A with α-Synuclein.
Filippo Favretto, Jeremy D Baker, Timo Strohäker, Loren B Andreas, Laura J Blair

Angew Chem Int Ed Engl· March 2020

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Spermidine/spermine-N-acetyltransferase ablation impacts tauopathy-induced polyamine stress response.
Leslie A Sandusky-Beltran, Andrii Kovalenko, Chao Ma, John Ivan T Calahatian, Devon S Placides, Jeremy D Baker

Alzheimers Res Ther· June 2019

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Repeated repeat problems: Combinatorial effect of C9orf72-derived dipeptide repeat proteins.
April L Darling, Leonid Breydo, Emma G Rivas, Niad T Gebru, Dali Zheng, Jeremy D Baker

Int J Biol Macromol· April 2019

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Hsp90 Heterocomplexes Regulate Steroid Hormone Receptors: From Stress Response to Psychiatric Disease.
Jeremy D Baker, Ilayda Ozsan, Santiago Rodriguez Ospina, Danielle Gulick, Laura J Blair

Int J Mol Sci· December 2018

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Structure and pro-toxic mechanism of the human Hsp90/PPIase/Tau complex.
Javier Oroz, Bliss J Chang, Piotr Wysoczanski, Chung-Tien Lee, Ángel Pérez-Lara, Jeremy D Baker

Nat Commun· October 2018

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Targeting the FKBP51/GR/Hsp90 Complex to Identify Functionally Relevant Treatments for Depression and PTSD.
Jonathan J Sabbagh, Ricardo A Cordova, Dali Zheng, Marangelie Criado-Marrero, Andrea Lemus, Jeremy D Baker

ACS Chem Biol· August 2018

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Hsp90 activator Aha1 drives production of pathological tau aggregates.
Lindsey B Shelton, Jeremy D Baker, Dali Zheng, Leia E Sullivan, Parth K Solanki

Proc Natl Acad Sci U S A· September 2017

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Human cyclophilin 40 unravels neurotoxic amyloids.
Jeremy D Baker, Lindsey B Shelton, Dali Zheng, Filippo Favretto, Bryce A Nordhues

PLoS Biol· June 2017

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Inhibition of Both Hsp70 Activity and Tau Aggregation in Vitro Best Predicts Tau Lowering Activity of Small Molecules.
Mackenzie D Martin, Jeremy D Baker, Amirthaa Suntharalingam, Bryce A Nordhues, Lindsey B Shelton

ACS Chem Biol· July 2016

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DnaJ/Hsc70 chaperone complexes control the extracellular release of neurodegenerative-associated proteins.
Sarah N Fontaine, Dali Zheng, Jonathan J Sabbagh, Mackenzie D Martin, Dale Chaput, Jeremy Baker

EMBO J· July 2016

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C9ORF72 poly(GA) aggregates sequester and impair HR23 and nucleocytoplasmic transport proteins.
Yong-Jie Zhang, Tania F Gendron, Jonathan C Grima, Hiroki Sasaguri, Karen Jansen-West, Jeremy D Baker

Nat Neurosci· May 2016

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Cellular factors modulating the mechanism of tau protein aggregation.
Sarah N Fontaine, Jonathan J Sabbagh, Jeremy Baker, Carlos R Martinez-Licha, April Darling

Cell Mol Life Sci· May 2015

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The emerging role of peptidyl-prolyl isomerase chaperones in tau oligomerization, amyloid processing, and Alzheimer's disease.
Laura J Blair, Jeremy D Baker, Jonathan J Sabbagh, Chad A Dickey

J Neurochem· April 2015

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Mesh wrapping for severe hepatic injury: a beneficial option in the trauma surgeon's armamentarium.
Ryan Kennedy, Sidney B Brevard, Patrick Bosarge, Jon D Simmons, Mohammed A Frotan, Jeremy A Baker

Am J Surg· March 2015

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Prehospital clinical clearance of the cervical spine: a prospective study.
Richard P Gonzalez, Glenn R Cummings, Jeremy A Baker, Amin M Frotan, Jon D Simmons

Am Surg· November 2013

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Clinical clearance of the cervical spine in patients with distracting injuries: It is time to dispel the myth.
Melanie K Rose, Lindy M Rosal, Richard P Gonzalez, Jack W Rostas, Jeremy A Baker

J Trauma Acute Care Surg· August 2012

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