Publications by authors named "Jerry Nedelman"

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Population pharmacokinetics of TBAJ-587 and its main metabolites-Evaluation of different loading dose strategies and early dose selection.
Albin A M Leding, Paul Bruinenberg, Almari Conradie, Jerry Nedelman, Antonio Lombardi

Br J Clin Pharmacol· November 2025

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A Novel Approach to Evaluating the Design of Pediatric Pharmacokinetic Studies Focused on Accurate Dose Selection.
Yuanxi Zou, Jerry Nedelman, Mats O Karlsson, Elin M Svensson

Clin Pharmacokinet· September 2025

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Pharmacokinetics, tolerability, and safety of TBI-223, a novel oxazolidinone, in healthy participants.
Antonio Lombardi, Fran Pappas, Paul Bruinenberg, Jerry Nedelman, Rajneesh Taneja

Antimicrob Agents Chemother· April 2025

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Pharmacokinetics and safety of TBAJ-876, a novel antimycobacterial diarylquinoline, in healthy subjects.
Antonio Lombardi, Fran Pappas, Jerry Nedelman, Dean Hickman, Sarah Jaw-Tsai

Antimicrob Agents Chemother· October 2024

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Characterizing Absorption Properties of Dispersible Pretomanid Tablets Using Population Pharmacokinetic Modelling.
Yuanxi Zou, Jerry Nedelman, Antonio Lombardi, Frances Pappas, Mats O Karlsson

Clin Pharmacokinet· November 2022

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Proposed Linezolid Dosing Strategies to Minimize Adverse Events for Treatment of Extensively Drug-Resistant Tuberculosis.
Marjorie Z Imperial, Jerry R Nedelman, Francesca Conradie, R M Savic

Clin Infect Dis· May 2022

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Single Ascending-Dose Study To Evaluate the Safety, Tolerability, and Pharmacokinetics of Sutezolid in Healthy Adult Subjects.
Paul Bruinenberg, Jerry Nedelman, Tian J Yang, Fran Pappas, Dan Everitt

Antimicrob Agents Chemother· April 2022

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Phase 1 Study of the Effects of the Tuberculosis Treatment Pretomanid, Alone and in Combination With Moxifloxacin, on the QTc Interval in Healthy Volunteers.
Mengchun Li, George A Saviolakis, Wael El-Amin, Mamodikoe K Makhene, Blaire Osborn, Jerry Nedelman

Clin Pharmacol Drug Dev· June 2021

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An Exposure-Response Perspective on the Clinical Dose of Pretomanid.
Jerry R Nedelman, David H Salinger, Vishak Subramoney, Rob Woolson, Karen Wade

Antimicrob Agents Chemother· December 2020

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Reply to Kim et al., "Optimal Dose or Optimal Exposure? Consideration for Linezolid in Tuberculosis Treatment".
Andreas H Diacon, Veronique R De Jager, Rodney Dawson, Kim Narunsky, Naadira Vanker, Jerry Nedelman

Antimicrob Agents Chemother· June 2020

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Fourteen-Day Bactericidal Activity, Safety, and Pharmacokinetics of Linezolid in Adults with Drug-Sensitive Pulmonary Tuberculosis.
Andreas H Diacon, Veronique R De Jager, Rodney Dawson, Kim Narunsky, Naadira Vanker, Jerry Nedelman

Antimicrob Agents Chemother· March 2020

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Daily Dosing for Bedaquiline in Patients with Tuberculosis.
David H Salinger, Jerry R Nedelman, Carl Mendel, Melvin Spigelman, David J Hermann

Antimicrob Agents Chemother· November 2019

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Long-Term Effects on QT Prolongation of Pretomanid Alone and in Combinations in Patients with Tuberculosis.
Hanbin Li, David H Salinger, Daniel Everitt, Mengchun Li, Angelo Del Parigi, Jerry R Nedelman

Antimicrob Agents Chemother· October 2019

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Population Pharmacokinetics of the Antituberculosis Agent Pretomanid.
David H Salinger, Vishak Subramoney, Daniel Everitt, Jerry R Nedelman

Antimicrob Agents Chemother· October 2019

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Population pharmacokinetics-pharmacodynamics of oral everolimus in patients with seizures associated with tuberous sclerosis complex.
François Pierre Combes, Guillaume Baneyx, Neva Coello, Penny Zhu, William Sallas, Jerry Nedelman

J Pharmacokinet Pharmacodyn· October 2018

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Population Pharmacokinetics of Subcutaneous Pasireotide in Healthy Volunteers and Cushing's Disease Patients.
Jerry Nedelman, Roland Fisch, Ke Hu, Ines Paule, Jocelyn Zhou

Clin Pharmacokinet· July 2018

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Utility of Exposure-Response Analysis in Regulatory Decision on the Selection of Starting Dose of Pasireotide for Cushing Disease.
Jingyu Yu, Sang Chung, Immo Zadezensky, Ke Hu, Christelle Darstein, Jerry Nedelman

J Clin Pharmacol· August 2016

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Population pharmacokinetics of sonidegib (LDE225), an oral inhibitor of hedgehog pathway signaling, in healthy subjects and in patients with advanced solid tumors.
Varun Goel, Eunju Hurh, Andrew Stein, Jerry Nedelman, Jocelyn Zhou

Cancer Chemother Pharmacol· April 2016

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Population pharmacokinetics of intravenous and oral panobinostat in patients with hematologic and solid tumors.
Marina Savelieva, Margaret M Woo, Horst Schran, Song Mu, Jerry Nedelman

Eur J Clin Pharmacol· June 2015

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Correlating changes in lung function with patient outcomes in chronic obstructive pulmonary disease: a pooled analysis.
Paul W Jones, James F Donohue, Jerry Nedelman, Steve Pascoe, Gregory Pinault

Respir Res· December 2011

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A therapeutic drug monitoring algorithm for refining the imatinib trough level obtained at different sampling times.
Yanfeng Wang, Yen Lin Chia, Jerry Nedelman, Horst Schran, Francois-Xavier Mahon

Ther Drug Monit· October 2009

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Diagnostics for confounding in PK/PD models for oxcarbazepine.
Jerry R Nedelman, Donald B Rubin, Lewis B Sheiner

Stat Med· January 2007

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On some "disadvantages" of the population approach.
Jerry R Nedelman

AAPS J· October 2005

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Pharmacokinetic-pharmacodynamic comparison of a novel multiligand somatostatin analog, SOM230, with octreotide in patients with acromegaly.
Peiming Ma, Yanfeng Wang, Joost van der Hoek, Jerry Nedelman, Horst Schran

Clin Pharmacol Ther· July 2005

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Pharmacodynamics of single doses of the novel immunosuppressant FTY720 in stable renal transplant patients.
Klemens Budde, Robert L Schmouder, Bjorn Nashan, Reinhard Brunkhorst, Peter W Lücker, Jerry Nedelman

Am J Transplant· July 2003

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