Publications by authors named "Jesse Mobbs"

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Structural basis for Porcupine inhibition.
Katrina A Black, Jesse I Mobbs, Hariprasad Venugopal, Toby A Dite, Andrew Leis

Commun Chem· November 2025

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Structure-guided allosteric modulation of the delta opioid receptor.
Jesse I Mobbs, M Deborah Nguyen, Owindeep Deo, Damian Bartuzi, Hariprasad Venugopal

bioRxiv· October 2025

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Molecular basis of ligand binding and receptor activation at the human A adenosine receptor.
Liudi Zhang, Jesse I Mobbs, Felix M Bennetts, Hariprasad Venugopal, Anh T N Nguyen

Nat Commun· August 2025

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Cryo-EM reveals an extrahelical allosteric binding site at the M mAChR.
Wessel A C Burger, Jesse I Mobbs, Bhavika Rana, Jinan Wang, Keya Joshi

Nat Commun· July 2025

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Cryo-EM reveals a new allosteric binding site at the M mAChR.
Wessel A C Burger, Jesse I Mobbs, Bhavika Rana, Jinan Wang, Keya Joshi

bioRxiv· February 2025

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High-resolution cryo-EM using a common LaB 120-keV electron microscope equipped with a sub-200-keV direct electron detector.
Hariprasad Venugopal, Jesse Mobbs, Cyntia Taveneau, Daniel R Fox, Ziva Vuckovic

Sci Adv· January 2025

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Structural insights into the human P2X1 receptor and ligand interactions.
Felix M Bennetts, Hariprasad Venugopal, Alisa Glukhova, Jesse I Mobbs, Sabatino Ventura

Nat Commun· September 2024

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Cholesterol-dependent dynamic changes in the conformation of the type 1 cholecystokinin receptor affect ligand binding and G protein coupling.
Kaleeckal G Harikumar, Peishen Zhao, Brian P Cary, Xiaomeng Xu, Aditya J Desai, Jesse I Mobbs

PLoS Biol· July 2024

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Cryo-EM structures of human arachidonate 12S-lipoxygenase bound to endogenous and exogenous inhibitors.
Jesse I Mobbs, Katrina A Black, Michelle Tran, Wessel A C Burger, Hariprasad Venugopal

Blood· October 2023

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Xanomeline displays concomitant orthosteric and allosteric binding modes at the M mAChR.
Wessel A C Burger, Vi Pham, Ziva Vuckovic, Alexander S Powers, Jesse I Mobbs

Nat Commun· September 2023

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Complimentary electrostatics dominate T-cell receptor binding to a psoriasis-associated peptide antigen presented by human leukocyte antigen C∗06:02.
Sushma Anand, Dene R Littler, Jesse I Mobbs, Asolina Braun, Daniel G Baker

J Biol Chem· July 2023

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Pharmacological hallmarks of allostery at the M4 muscarinic receptor elucidated through structure and dynamics.
Ziva Vuckovic, Jinan Wang, Vi Pham, Jesse I Mobbs, Matthew J Belousoff

Elife· May 2023

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The impact of cryo-EM on determining allosteric modulator-bound structures of G protein-coupled receptors.
Liudi Zhang, Jesse I Mobbs, Lauren T May, Alisa Glukhova, David M Thal

Curr Opin Struct Biol· April 2023

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The P2X1 receptor as a therapeutic target.
Felix M Bennetts, Jesse I Mobbs, Sabatino Ventura, David M Thal

Purinergic Signal· December 2022

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Structures of the human cholecystokinin 1 (CCK1) receptor bound to Gs and Gq mimetic proteins provide insight into mechanisms of G protein selectivity.
Jesse I Mobbs, Matthew J Belousoff, Kaleeckal G Harikumar, Sarah J Piper, Xiaomeng Xu

PLoS Biol· June 2021

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Applications of NMR and ITC for the Study of the Kinetics of Carbohydrate Binding by AMPK β-Subunit Carbohydrate-Binding Modules.
Paul R Gooley, Ann Koay, Jesse I Mobbs

Methods Mol Biol· January 2019

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Unravelling the Carbohydrate-Binding Preferences of the Carbohydrate-Binding Modules of AMP-Activated Protein Kinase.
Jesse I Mobbs, Alex Di Paolo, Riley D Metcalfe, Emily Selig, David I Stapleton

Chembiochem· February 2018

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The molecular basis for peptide repertoire selection in the human leucocyte antigen (HLA) C*06:02 molecule.
Jesse I Mobbs, Patricia T Illing, Nadine L Dudek, Andrew G Brooks, Daniel G Baker

J Biol Chem· October 2017

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Structural and regulatory diversity shape HLA-C protein expression levels.
Gurman Kaur, Stephanie Gras, Jesse I Mobbs, Julian P Vivian, Adrian Cortes

Nat Commun· June 2017

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Determinants of oligosaccharide specificity of the carbohydrate-binding modules of AMP-activated protein kinase.
Jesse I Mobbs, Ann Koay, Alex Di Paolo, Michael Bieri, Emma J Petrie

Biochem J· June 2015

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AMP-activated protein kinase β-subunit requires internal motion for optimal carbohydrate binding.
Michael Bieri, Jesse I Mobbs, Ann Koay, Gavin Louey, Yee-Foong Mok

Biophys J· January 2012

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