Publications by authors named "Jessica Basso"

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A Phase IIa, Single-Blind, Placebo-Controlled, Parallel-Group Study to Assess Safety, Tolerability, and Pharmacokinetics/Pharmacodynamics of Brensocatib in Adults with Cystic Fibrosis.
Michael W Konstan, James J Tolle, Emily DiMango, Patrick A Flume, Helen Usansky, Jessica Basso

Clin Pharmacokinet· October 2025

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Pharmacological inhibition of cathepsin S and of NSPs-AAP-1 (a novel, alternative protease driving the activation of neutrophil serine proteases).
Roxane Domain, Seda Seren, Uwe Jerke, Manousos Makridakis, Kuan-Ju Chen, Jessica Basso

Biochem Pharmacol· November 2024

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Brensocatib (an oral, reversible inhibitor of dipeptidyl peptidase-1) attenuates disease progression in two animal models of rheumatoid arthritis.
Patrick P McDonald, Franziska Graf Leifer, Jessica Basso, Dan Lasala, Dedong Li

Front Immunol· August 2023

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Brensocatib, an oral, reversible inhibitor of dipeptidyl peptidase 1, mitigates interferon-α-accelerated lupus nephritis in mice.
Kuan-Ju Chen, Jimin Zhang, Daniel LaSala, Jessica Basso, Donald Chun

Front Immunol· July 2023

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The pharmacokinetic profile of brensocatib and its effect on pharmacodynamic biomarkers including NE, PR3, and CatG in various rodent species.
Jessica Basso, Kuan-Ju Chen, Yuchen Zhou, Lilly Mark, Daniel LaSala

Front Pharmacol· July 2023

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Dipeptidyl peptidase-1 inhibition with brensocatib reduces the activity of all major neutrophil serine proteases in patients with bronchiectasis: results from the WILLOW trial.
David Cipolla, Jimin Zhang, Brice Korkmaz, James D Chalmers, Jessica Basso

Respir Res· May 2023

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Correction for Plaunt et al., "Development and Preclinical Evaluation of New Inhaled Lipoglycopeptides for the Treatment of Persistent Pulmonary Methicillin-Resistant Staphylococcus aureus Infections".
Adam J Plaunt, Sasha J Rose, Jeong Yeon Kang, Kuan-Ju Chen, Daniel LaSala, Jessica Basso

Antimicrob Agents Chemother· November 2022

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An optimized method of extracting and quantifying active Neutrophil serine proteases from human whole blood cells.
Jessica Basso, Jimin Zhang, Daniel Lasala, Sasha J Rose, Kuan-Ju Chen

PLoS One· September 2022

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Development and Preclinical Evaluation of New Inhaled Lipoglycopeptides for the Treatment of Persistent Pulmonary Methicillin-Resistant Staphylococcus aureus Infections.
Adam J Plaunt, Sasha J Rose, Jeong Yeon Kang, Kuan-Ju Chen, Daniel LaSala, Jessica Basso

Antimicrob Agents Chemother· June 2021

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Updated strategies in the management of acute variceal haemorrhage.
Jerome Edelson, Jessica E Basso, Don C Rockey

Curr Opin Gastroenterol· May 2021

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