Publications by authors named "Jessica Schneck"

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Optimization of Potent and Selective Cyclohexyl Acid ERAP1 Inhibitors Using Structure- and Property-Based Drug Design.
Ross P Hryczanek, Andrew S Hackett, Paul Rowland, Chun-Wa Chung, Máire A Convery, Jessica L Schneck

ACS Med Chem Lett· December 2024

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Novel WRN Helicase Inhibitors Selectively Target Microsatellite-Unstable Cancer Cells.
Gabriele Picco, Yanhua Rao, Angham Al Saedi, Yang Lee, Sara F Vieira, Jessica L Schneck

Cancer Discov· August 2024

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Exploration of the P1 residue in 3CL protease inhibitors leading to the discovery of a 2-tetrahydrofuran P1 replacement.
Linda S Barton, James F Callahan, Juan Cantizani, Nestor O Concha, Ignacio Cotillo Torrejon, Jessica L Schneck

Bioorg Med Chem· February 2024

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A highly selective, cell-permeable furin inhibitor BOS-318 rescues key features of cystic fibrosis airway disease.
Lisa E J Douglas, James A Reihill, Melisa W Y Ho, Jeffrey M Axten, Nino Campobasso, Jessica L Schneck

Cell Chem Biol· June 2022

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Targeting the Regulatory Site of ER Aminopeptidase 1 Leads to the Discovery of a Natural Product Modulator of Antigen Presentation.
John Liddle, Jonathan P Hutchinson, Semra Kitchen, Paul Rowland, Margarete Neu, Jessica L Schneck

J Med Chem· March 2020

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A Scalable Platform for Producing Recombinant Nucleosomes with Codified Histone Methyltransferase Substrate Preferences.
Patrick J McDevitt, Jessica L Schneck, Elsie Diaz, Wangfang Hou, Michael J Huddleston

Protein Expr Purif· December 2019

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Author Correction: Design of amidobenzimidazole STING receptor agonists with systemic activity.
Joshi M Ramanjulu, G Scott Pesiridis, Jingsong Yang, Nestor Concha, Robert Singhaus, Jessica L Schneck

Nature· June 2019

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Design of amidobenzimidazole STING receptor agonists with systemic activity.
Joshi M Ramanjulu, G Scott Pesiridis, Jingsong Yang, Nestor Concha, Robert Singhaus, Jessica L Schneck

Nature· December 2018

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Inhibitors of LexA Autoproteolysis and the Bacterial SOS Response Discovered by an Academic-Industry Partnership.
Charlie Y Mo, Matthew J Culyba, Trevor Selwood, Jeffrey M Kubiak, Zachary M Hostetler, Jessica Schneck

ACS Infect Dis· March 2018

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Discovery and Characterization of a Class of Pyrazole Inhibitors of Bacterial Undecaprenyl Pyrophosphate Synthase.
Nestor Concha, Jianzhong Huang, Xiaopeng Bai, Andrew Benowitz, Pat Brady, Jessica Schneck

J Med Chem· August 2016

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Nucleosome Binding Alters the Substrate Bonding Environment of Histone H3 Lysine 36 Methyltransferase NSD2.
Myles B Poulin, Jessica L Schneck, Rosalie E Matico, Wangfang Hou, Patrick J McDevitt

J Am Chem Soc· June 2016

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Transition state for the NSD2-catalyzed methylation of histone H3 lysine 36.
Myles B Poulin, Jessica L Schneck, Rosalie E Matico, Patrick J McDevitt, Michael J Huddleston

Proc Natl Acad Sci U S A· February 2016

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GSK356278, a potent, selective, brain-penetrant phosphodiesterase 4 inhibitor that demonstrates anxiolytic and cognition-enhancing effects without inducing side effects in preclinical species.
A Richard Rutter, Alessandro Poffe, Palmina Cavallini, T Gregg Davis, Jessica Schneck

J Pharmacol Exp Ther· July 2014

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Quinoline 3-sulfonamides inhibit lactate dehydrogenase A and reverse aerobic glycolysis in cancer cells.
Julia Billiard, Jennifer B Dennison, Jacques Briand, Roland S Annan, Deping Chai, Jessica L Schneck

Cancer Metab· September 2013

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The amino-acid substituents of dipeptide substrates of cathepsin C can determine the rate-limiting steps of catalysis.
Jon K Rubach, Guanglei Cui, Jessica L Schneck, Amy N Taylor, Baoguang Zhao

Biochemistry· September 2012

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Methyltransferases prefer monomer over core-trimmed nucleosomes as in vitro substrates.
Yong Jiang, Jessica L Schneck, Maggie Grimes, Amy N Taylor, Wangfang Hou

Anal Biochem· August 2011

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Discovery of novel cyanamide-based inhibitors of cathepsin C.
Dramane Lainé, Michael Palovich, Brent McCleland, Emilie Petitjean, Isabelle Delhom, Jessica Schneck

ACS Med Chem Lett· February 2011

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Kinetic mechanism and rate-limiting steps of focal adhesion kinase-1.
Jessica L Schneck, Jacques Briand, Stephanie Chen, Ruth Lehr, Patrick McDevitt

Biochemistry· August 2010

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Identification of PDE4B Over 4D subtype-selective inhibitors revealing an unprecedented binding mode.
Michael Kranz, Michael Wall, Brian Evans, Afjal Miah, Stuart Ballantine, Jessica Schneck

Bioorg Med Chem· July 2009

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Chemical mechanism of a cysteine protease, cathepsin C, as revealed by integration of both steady-state and pre-steady-state solvent kinetic isotope effects.
Jessica L Schneck, James P Villa, Patrick McDevitt, Michael S McQueney, Sara H Thrall

Biochemistry· August 2008

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A simple assay for detection of small-molecule redox activity.
Leng A Lor, Jessica Schneck, Dean E McNulty, Elsie Diaz, Martin Brandt

J Biomol Screen· September 2007

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Effects of tonicity, digestive enzymes and bile salts, and nutrient media on the survival of excysted metacercariae of Echinostoma caproni.
Bernard Fried, Jessica L Schneck, Elizabeth L Ponder

Parasitol Res· May 2004

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Effects of tonicity on the release of neutral lipids in Echinostoma caproni adults and observations on lipids in excysted metacercariae.
Jessica L Schneck, Bernard Fried, Joseph Sherma

Parasitol Res· March 2004

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