Publications by authors named "Johan Desmet"

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Cell-penetrating Alphabody protein scaffolds for intracellular drug targeting.
Erwin Pannecoucke, Maaike Van Trimpont, Johan Desmet, Tim Pieters, Lindy Reunes

Sci Adv· March 2021

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Structural basis of IL-23 antagonism by an Alphabody protein scaffold.
Johan Desmet, Kenneth Verstraete, Yehudi Bloch, Eric Lorent, Yurong Wen

Nat Commun· October 2014

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Affinity maturation by semi-rational approaches.
Rodrigo Barderas, Johan Desmet, Philippe Alard, J Ignacio Casal

Methods Mol Biol· December 2012

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Binding of CDR-derived peptides is mechanistically different from that of high-affinity parental antibodies.
Peter Timmerman, Susana G Shochat, Johan Desmet, Rodrigo Barderas, Jose Ignacio Casal

J Mol Recognit· March 2011

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A combinatorial approach for the design of complementarity-determining region-derived peptidomimetics with in vitro anti-tumoral activity.
Peter Timmerman, Rodrigo Barderas, Johan Desmet, Danièle Altschuh, Susana Shochat

J Biol Chem· December 2009

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Affinity maturation of antibodies assisted by in silico modeling.
Rodrigo Barderas, Johan Desmet, Peter Timmerman, Rob Meloen, J Ignacio Casal

Proc Natl Acad Sci U S A· July 2008

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Diagnostic and treatment issues in postamputation pain after landmine injury.
Philip Wiffen, Jacques Meynadier, Michel Dubois, Calude Thurel, Johan deSmet

Pain Med· April 2007

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Rational humanization of the powerful antithrombotic anti-GPIbalpha antibody: 6B4.
Alexandre Fontayne, Karen Vanhoorelbeke, Inge Pareyn, Isabel Van Rompaey, Muriel Meiring, Johan Desmet

Thromb Haemost· November 2006

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Humanization by variable domain resurfacing and grafting on a human IgG4, using a new approach for determination of non-human like surface accessible framework residues based on homology modelling of variable domains.
Stephanie Staelens, Johan Desmet, Thu Hoa Ngo, Stephan Vauterin, Inge Pareyn

Mol Immunol· March 2006

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Anchor profiles of HLA-specific peptides: analysis by a novel affinity scoring method and experimental validation.
Johan Desmet, Geert Meersseman, Nathalie Boutonnet, Jurgen Pletinckx, Krista De Clercq

Proteins· January 2005

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Fast and accurate side-chain topology and energy refinement (FASTER) as a new method for protein structure optimization.
Johan Desmet, Jan Spriet, Ignace Lasters

Proteins· July 2002

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