Publications by authors named "Rob Meloen"

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Proteasome inhibition and mechanism of resistance to a synthetic, library-based hexapeptide.
Ruud Oerlemans, Celia R Berkers, Yehuda G Assaraf, George L Scheffer, Godefridus J Peters, Rob H Meloen

Invest New Drugs· October 2018

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Targeted vaccination against the bevacizumab binding site on VEGF using 3D-structured peptides elicits efficient antitumor activity.
Madelon Q Wentink, Tilman M Hackeng, Sebastien P Tabruyn, Wouter C Puijk, Klaus Schwamborn, Rob H Meloen

Proc Natl Acad Sci U S A· November 2016

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Binding of CDR-derived peptides is mechanistically different from that of high-affinity parental antibodies.
Peter Timmerman, Susana G Shochat, Johan Desmet, Rodrigo Barderas, Jose Ignacio Casal, Rob H Meloen

J Mol Recognit· March 2011

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A combinatorial approach for the design of complementarity-determining region-derived peptidomimetics with in vitro anti-tumoral activity.
Peter Timmerman, Rodrigo Barderas, Johan Desmet, Danièle Altschuh, Susana Shochat, Rob H Meloen

J Biol Chem· December 2009

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Heterologous stacking of prion protein peptides reveals structural details of fibrils and facilitates complete inhibition of fibril growth.
Ronald S Boshuizen, Veronica Schulz, Michela Morbin, Giulia Mazzoleni, Rob H Meloen

J Biol Chem· May 2009

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SUMO assay with peptide arrays on solid support: insights into SUMO target sites.
Klaus Schwamborn, Puck Knipscheer, Evert van Dijk, Willem J van Dijk, Titia K Sixma, Rob H Meloen

J Biochem· July 2008

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Affinity maturation of antibodies assisted by in silico modeling.
Rodrigo Barderas, Johan Desmet, Peter Timmerman, Rob Meloen, J Ignacio Casal

Proc Natl Acad Sci U S A· July 2008

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Functional reconstruction and synthetic mimicry of a conformational epitope using CLIPS technology.
Peter Timmerman, Wouter C Puijk, Rob H Meloen

J Mol Recognit· June 2008

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Designing antibodies for the inhibition of gastrin activity in tumoral cell lines.
Rodrigo Barderas, Susana Shochat, Peter Timmerman, Martine J Hollestelle, Jorge L Martínez-Torrecuadrada, Rob Meloen

Int J Cancer· May 2008

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Characterization of gastrin-cholecystokinin 2 receptor interaction in relation to c-fos induction.
Martine J Hollestelle, Peter Timmerman, Rob H Meloen, Jo W M Höppener

Endocr Relat Cancer· March 2008

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Polyanion induced fibril growth enables the development of a reproducible assay in solution for the screening of fibril interfering compounds, and the investigation of the prion nucleation site.
Ronald S Boshuizen, Michela Morbin, Giulia Mazzoleni, Fabrizio Tagliavini, Rob H Meloen

Amyloid· September 2007

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A fast mutagenesis procedure to recover soluble and functional scFvs containing amber stop codons from synthetic and semisynthetic antibody libraries.
Rodrigo Barderas, Susana Shochat, Jorge Martínez-Torrecuadrada, Danièle Altschuh, Rob Meloen

J Immunol Methods· May 2006

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Antifungal activity of synthetic peptides derived from Impatiens balsamina antimicrobial peptides Ib-AMP1 and Ib-AMP4.
Karin Thevissen, Isabelle E J A François, Lolke Sijtsma, Aart van Amerongen, Wim M M Schaaper, Rob Meloen

Peptides· July 2005

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Rapid and quantitative cyclization of multiple peptide loops onto synthetic scaffolds for structural mimicry of protein surfaces.
Peter Timmerman, Joris Beld, Wouter C Puijk, Rob H Meloen

Chembiochem· May 2005

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Novel rabies virus-neutralizing epitope recognized by human monoclonal antibody: fine mapping and escape mutant analysis.
Wilfred E Marissen, R Arjen Kramer, Amy Rice, William C Weldon, Michael Niezgoda, Rob H Meloen

J Virol· April 2005

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Fast track selection of immunogens for novel vaccines through visualisation of the early onset of the B-cell response.
Antonio Scibelli, Robbert G van der Most, Johan A Turkstra, Mark P Ariaans, Ger Arkesteijn, Rob H Meloen

Vaccine· March 2005

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Bioactive peptides based on diversity libraries, supramolecular chemistry and rational design: a new class of peptide drugs. Introduction.
Rob Meloen, Peter Timmerman, Hans Langedijk

Mol Divers· December 2004

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Mapping of a discontinuous and highly conformational binding site on follicle stimulating hormone subunit-beta (FSH-beta) using domain Scan and Matrix Scan technology.
Peter Timmerman, Evert Van Dijk, Wouter Puijk, Wim Schaaper, Jerry Slootstra, Rob H Meloen

Mol Divers· December 2004

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An in vitro screening assay based on synthetic prion protein peptides for identification of fibril-interfering compounds.
Ronald S Boshuizen, Jan P M Langeveld, Mario Salmona, Alun Williams, Rob H Meloen

Anal Biochem· October 2004

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Identification of an interleukin-15alpha receptor-binding site on human interleukin-15.
Jérôme Bernard, Catherine Harb, Erwan Mortier, Agnès Quéméner, Rob H Meloen

J Biol Chem· June 2004

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Multidrug-resistant tumor cells remain sensitive to a recombinant interleukin-4-Pseudomonas exotoxin, except when overexpressing the multidrug resistance protein MRP1.
Mariska C de Jong, George L Scheffer, Henk J Broxterman, Jan H Hooijberg, Jerry W Slootstra, Rob H Meloen

Clin Cancer Res· October 2003

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Discovery and in vivo evaluation of new melanocortin-4 receptor-selective peptides.
Wouter A J Nijenhuis, John A W Kruijtzer, Nienke Wanders, Dorien H Vrinten, Keith M Garner, Rob H Meloen

Peptides· February 2003

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Functional analysis of synthetic insectatachykinin analogs on recombinant neurokinin receptor expressing cell lines.
Herbert Torfs, Karl E Akerman, Ronald J Nachman, Hendrica B Oonk, Michel Detheux, Rob H Meloen

Peptides· November 2002

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A peptide mimic of an antigenic loop of alpha-human chorionic gonadotropin hormone: solution structure and interaction with a llama V(HH) domain.
Gilles Ferrat, Jean-Guillaume Renisio, Xavier Morelli, Jerry Slootstra, Rob Meloen

Biochem J· September 2002

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Active immunization against gonadotrophin-releasing hormone in Chinese male pigs: effects of dose on antibody titer, hormone levels and sexual development.
Xian Y Zeng, Johan A Turkstra, Rob H Meloen, Xian Y Liu, Fa Q Chen

Anim Reprod Sci· April 2002

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