Publications by authors named "Peter Timmerman"

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Chemokine-Binding All-D-CLIPS Peptides Identified Using Mirror-Image Phage Display.
Stepan S Denisov, Emilia L Bialek, Fabio Beretta, Gintare Smagurauskaite, Hans Ippel, Peter Timmerman

ACS Chem Biol· November 2025

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Molecular Detection of Venous Thrombosis in Mouse Models Using SPECT/CT.
Annemiek Dickhout, Pieter Van de Vijver, Nicole Bitsch, Stefan J van Hoof, Stella L G D Thomassen, Peter Timmerman

Biomolecules· June 2022

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Bicyclic RGD peptides enhance nerve growth in synthetic PEG-based Anisogels.
Sitara Vedaraman, Dominik Bernhagen, Tamas Haraszti, Christopher Licht, Arturo Castro Nava, Peter Timmerman

Biomater Sci· June 2021

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A Phase I Open-Label Clinical Trial Evaluating the Therapeutic Vaccine hVEGF26-104/RFASE in Patients with Advanced Solid Malignancies.
Ruben S A Goedegebuure, Madelon Q Wentink, Hans J van der Vliet, Peter Timmerman, Arjan W Griffioen

Oncologist· February 2021

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High-Affinity αβ-Integrin-Selective Bicyclic RGD Peptides Identified via Screening of Designed Random Libraries.
Dominik Bernhagen, Vanessa Jungbluth, Nestor Gisbert Quilis, Jakub Dostalek, Paul B White, Peter Timmerman

ACS Comb Sci· August 2019

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Synthesis of Constrained Tetracyclic Peptides by Consecutive CEPS, CLIPS, and Oxime Ligation.
Dieuwertje E Streefkerk, Marcel Schmidt, Johannes H Ippel, Tilman M Hackeng, Timo Nuijens, Peter Timmerman

Org Lett· April 2019

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Bicyclic RGD Peptides with Exquisite Selectivity for the Integrin αβ Receptor Using a "Random Design" Approach.
Dominik Bernhagen, Vanessa Jungbluth, Nestor Gisbert Quilis, Jakub Dostalek, Paul B White, Peter Timmerman

ACS Comb Sci· March 2019

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Bicyclic RGD peptides with high integrin α β and α β affinity promote cell adhesion on elastin-like recombinamers.
Filippo Cipriani, Dominik Bernhagen, Carmen García-Arévalo, Israel González de Torre, Peter Timmerman

Biomed Mater· March 2019

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A One-Pot "Triple-C" Multicyclization Methodology for the Synthesis of Highly Constrained Isomerically Pure Tetracyclic Peptides.
Gaston J J Richelle, Marcel Schmidt, Hans Ippel, Tilman M Hackeng, Jan H van Maarseveen, Peter Timmerman

Chembiochem· September 2018

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General and Facile Route to Isomerically Pure Tricyclic Peptides Based on Templated Tandem CLIPS/CuAAC Cyclizations.
Gaston J J Richelle, Sumeet Ori, Henk Hiemstra, Jan H van Maarseveen, Peter Timmerman

Angew Chem Int Ed Engl· January 2018

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Editorial for the special issue on "constrained peptides".
Jan H van Maarseveen, Peter Timmerman

Drug Discov Today Technol· December 2017

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High-Affinity RGD-Knottin Peptide as a New Tool for Rapid Evaluation of the Binding Strength of Unlabeled RGD-Peptides to αβ, αβ, and αβ Integrin Receptors.
Dominik Bernhagen, Laura De Laporte, Peter Timmerman

Anal Chem· June 2017

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Reply to Marchiò et al.: Antitumor immune regulation by angiostatic therapy.
Madelon Q Wentink, Elisabeth J M Huijbers, Peter Timmerman, Arjan W Griffioen

Proc Natl Acad Sci U S A· April 2017

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Targeted vaccination against the bevacizumab binding site on VEGF using 3D-structured peptides elicits efficient antitumor activity.
Madelon Q Wentink, Tilman M Hackeng, Sebastien P Tabruyn, Wouter C Puijk, Klaus Schwamborn, Peter Timmerman

Proc Natl Acad Sci U S A· November 2016

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Reconstructing the discontinuous and conformational β1/β3-loop binding site on hFSH/hCG by using highly constrained multicyclic peptides.
Linde E J Smeenk, Drohpatie Timmers-Parohi, Joris J Benschop, Wouter C Puijk, Henk Hiemstra, Peter Timmerman

Chembiochem· January 2015

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Exploration of the design principles of a cell-penetrating bicylic peptide scaffold.
Rike Wallbrecher, Luc Depré, Wouter P R Verdurmen, Petra H Bovée-Geurts, Richard H van Duinkerken, Peter Timmerman

Bioconjug Chem· May 2014

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Folding dynamics of the Trp-cage miniprotein: evidence for a native-like intermediate from combined time-resolved vibrational spectroscopy and molecular dynamics simulations.
Heleen Meuzelaar, Kristen A Marino, Adriana Huerta-Viga, Matthijs R Panman, Linde E J Smeenk, Peter Timmerman

J Phys Chem B· October 2013

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Synthesis of water-soluble scaffolds for peptide cyclization, labeling, and ligation.
Linde E J Smeenk, Nicolas Dailly, Henk Hiemstra, Jan H van Maarseveen, Peter Timmerman

Org Lett· March 2012

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Monitoring selectivity in kinase-promoted phosphorylation of densely packed peptide monolayers using label-free electrochemical detection.
Elza Snir, Jos Joore, Peter Timmerman, Shlomo Yitzchaik

Langmuir· September 2011

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Epitope characterization and crystal structure of GA101 provide insights into the molecular basis for type I/II distinction of CD20 antibodies.
Gerhard Niederfellner, Alfred Lammens, Olaf Mundigl, Guy J Georges, Wolfgang Schaefer, Peter Timmerman

Blood· July 2011

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Binding of CDR-derived peptides is mechanistically different from that of high-affinity parental antibodies.
Peter Timmerman, Susana G Shochat, Johan Desmet, Rodrigo Barderas, Jose Ignacio Casal

J Mol Recognit· March 2011

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A combinatorial approach for the design of complementarity-determining region-derived peptidomimetics with in vitro anti-tumoral activity.
Peter Timmerman, Rodrigo Barderas, Johan Desmet, Danièle Altschuh, Susana Shochat

J Biol Chem· December 2009

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Affinity maturation of antibodies assisted by in silico modeling.
Rodrigo Barderas, Johan Desmet, Peter Timmerman, Rob Meloen, J Ignacio Casal

Proc Natl Acad Sci U S A· July 2008

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Acetylcholine detection at micromolar concentrations with the use of an artificial receptor-based fluorescence switch.
Nina Korbakov, Peter Timmerman, Nina Lidich, Benayahu Urbach, Amir Sa'ar

Langmuir· March 2008

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Characterization of gastrin-cholecystokinin 2 receptor interaction in relation to c-fos induction.
Martine J Hollestelle, Peter Timmerman, Rob H Meloen, Jo W M Höppener

Endocr Relat Cancer· March 2008

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