Publications by authors named "John Lock"

Claim this Profile

Mentions over time

Mentions by platform

Video Views

4,644

Total Likes

137

Extended Reach

116,708

Social Features

29
L
Large-scale drug screening in iPSC-derived motor neurons from sporadic ALS patients identifies a potential combinatorial therapy.
Christopher R Bye, Elizabeth Qian, Katherine Lim, Maciej Daniszewski, Fleur C Garton, John G Lock

Nat Neurosci· January 2026

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
E
Epithelial-mesenchymal cell state heterogeneity predetermines differential phospho-signaling responses to EGF stimulation.
Felix V Kohane, Chantelle Johnstone, Daniel P Neumann, Ihuan Gunawan, Tim Huang, John G Lock

Mol Biol Cell· January 2026

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Capillary constrictions prime cancer cell tumorigenicity through PIEZO1.
Giulia Silvani, Chantal Kopecky, Sara Romanazzo, Vanina Rodríguez, Ayan Das, John G Lock

Nat Commun· September 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
G
Gene-Corrected Basal Cells Restore CFTR In Vitro; Transplants Regenerate Epithelium in a Preclinical Sinus Model.
Katelin M Allan, Shaoyan Zhang, Sharon L Wong, Alexander Capraro, Alexandra McCarron, John G Lock

bioRxiv· July 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
E
Extensible Immunofluorescence (ExIF) accessibly generates high-plexity datasets by integrating standard 4-plex imaging data.
Ihuan Gunawan, Felix V Kohane, Moumitha Dey, Kathy Nguyen, Ye Zheng, John G Lock

Nat Commun· May 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Single Intravenous Dose Dalbavancin Pathway for the Treatment of Acute Bacterial Skin and Skin Structure Infections: Considerations for Emergency Department Implementation and Cost Savings.
Frank LoVecchio, Matthew W McCarthy, Xiaolan Ye, Alasdair D Henry, Quan V Doan, John L Lock

J Emerg Med· August 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
O
Outcomes of inadequate empiric therapy and timing of newer antibacterial therapy in hospitalized adults with culture-positive Enterobacterales and Pseudomonas aeruginosa: a multicenter analysis.
Todd Riccobene, Gang Ye, John Lock, Kalvin C Yu, ChinEn Ai

BMC Infect Dis· August 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
B
Bexagliflozin as an adjunct to metformin for the treatment of type 2 diabetes in adults: A 24-week, randomized, double-blind, placebo-controlled trial.
Yuan-Di Halvorsen, Annie L Conery, John Paul Lock, Wenjiong Zhou, Mason W Freeman

Diabetes Obes Metab· October 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
G
Genomic and Phenotypic Biomarkers for Precision Medicine Guidance in Advanced Prostate Cancer.
Fatemeh Davoudi, Afshin Moradi, Therese M Becker, John G Lock, Brian Abbey

Curr Treat Options Oncol· October 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
An introduction to representation learning for single-cell data analysis.
Ihuan Gunawan, Fatemeh Vafaee, Erik Meijering, John George Lock

Cell Rep Methods· August 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Copper chelation suppresses epithelial-mesenchymal transition by inhibition of canonical and non-canonical TGF-β signaling pathways in cancer.
Ensieh M Poursani, Daniele Mercatelli, Prahlad Raninga, Jessica L Bell, Federica Saletta, John G Lock

Cell Biosci· July 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Dalbavancin for the Treatment of Acute Bacterial Skin and Skin Structure Infection in Patients With Obesity or Diabetes: A Subgroup Analysis of Pooled Phase 3 Clinical Trials.
Todd Riccobene, John Lock, Rosie D Lyles, Benjamin Georgiades, Michael Nowak

Open Forum Infect Dis· June 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
A 96-week, double-blind, randomized controlled trial comparing bexagliflozin to glimepiride as an adjunct to metformin for the treatment of type 2 diabetes in adults.
Yuan-Di Halvorsen, John Paul Lock, Juan P Frias, Francisco José Tinahones, Dominik Dahl

Diabetes Obes Metab· January 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Choice of antibody is critical for specific and sensitive detection of androgen receptor splice variant-7 in circulating tumor cells.
Tanzila Khan, John G Lock, Yafeng Ma, David G Harman, Paul de Souza

Sci Rep· September 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
M
Mapping Phenotypic Plasticity upon the Cancer Cell State Landscape Using Manifold Learning.
Daniel B Burkhardt, Beatriz P San Juan, John G Lock, Smita Krishnaswamy, Christine L Chaffer

Cancer Discov· August 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
Population subgroup differences in the use of a COVID-19 chatbot.
Laura C Schubel, Deliya B Wesley, Ethan Booker, John Lock, Raj M Ratwani

NPJ Digit Med· February 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
The Prospect of Identifying Resistance Mechanisms for Castrate-Resistant Prostate Cancer Using Circulating Tumor Cells: Is Epithelial-to-Mesenchymal Transition a Key Player?
Tanzila Khan, Kieran F Scott, Therese M Becker, John Lock, Mohammed Nimir

Prostate Cancer· March 2020

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
H
High-Content Imaging of Unbiased Chemical Perturbations Reveals that the Phenotypic Plasticity of the Actin Cytoskeleton Is Constrained.
Nicole S Bryce, Tim W Failes, Justine R Stehn, Karen Baker, Stefan Zahler, John G Lock

Cell Syst· November 2019

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
A 24-week, randomized, double-blind, active-controlled clinical trial comparing bexagliflozin with sitagliptin as an adjunct to metformin for the treatment of type 2 diabetes in adults.
Yuan-Di Halvorsen, John P Lock, Wenjiong Zhou, Fang Zhu, Mason W Freeman

Diabetes Obes Metab· October 2019

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Chemical biology approaches targeting the actin cytoskeleton through phenotypic screening.
Nicole S Bryce, Edna C Hardeman, Peter W Gunning, John G Lock

Curr Opin Chem Biol· August 2019

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Clathrin-containing adhesion complexes.
John G Lock, Francesco Baschieri, Matthew C Jones, Jonathan D Humphries, Guillaume Montagnac

J Cell Biol· July 2019

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
R
Reticular adhesions are a distinct class of cell-matrix adhesions that mediate attachment during mitosis.
John G Lock, Matthew C Jones, Janet A Askari, Xiaowei Gong, Anna Oddone

Nat Cell Biol· November 2018

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
K
KIF13A-regulated RhoB plasma membrane localization governs membrane blebbing and blebby amoeboid cell migration.
Xiaowei Gong, Yuliia Didan, John G Lock, Staffan Strömblad

EMBO J· September 2018

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
Active and inactive β1 integrins segregate into distinct nanoclusters in focal adhesions.
Matthias Spiess, Pablo Hernandez-Varas, Anna Oddone, Helene Olofsson, Hans Blom, John G Lock

J Cell Biol· June 2018

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis