Publications by authors named "John Scheigetz"

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Difluoroethylamines as an amide isostere in inhibitors of cathepsin K.
Elise Isabel, Christophe Mellon, Michael J Boyd, Nathalie Chauret, Denis Deschênes, John Scheigetz

Bioorg Med Chem Lett· February 2011

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Investigation of ketone warheads as alternatives to the nitrile for preparation of potent and selective cathepsin K inhibitors.
Michael J Boyd, Sheldon N Crane, Joël Robichaud, John Scheigetz, W Cameron Black

Bioorg Med Chem Lett· February 2009

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Discovery of a potent and selective prostaglandin D2 receptor antagonist, [(3R)-4-(4-chloro-benzyl)-7-fluoro-5-(methylsulfonyl)-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl]-acetic acid (MK-0524).
Claudio F Sturino, Gary O'Neill, Nicolas Lachance, Michael Boyd, Carl Berthelette, John Scheigetz

J Med Chem· February 2007

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Identification of an indole series of prostaglandin D2 receptor antagonists.
Claudio F Sturino, Nicolas Lachance, Michael Boyd, Carl Berthelette, Marc Labelle, John Scheigetz

Bioorg Med Chem Lett· June 2006

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Beta-substituted cyclohexanecarboxamide: a nonpeptidic framework for the design of potent inhibitors of cathepsin K.
Sheldon N Crane, W Cameron Black, James T Palmer, Dana E Davis, Eduardo Setti, John Scheigetz

J Med Chem· February 2006

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Discovery of a substituted 8-arylquinoline series of PDE4 inhibitors: structure-activity relationship, optimization, and identification of a highly potent, well tolerated, PDE4 inhibitor.
Dwight Macdonald, Anthony Mastracchio, Hélène Perrier, Daniel Dubé, Michel Gallant, John Scheigetz

Bioorg Med Chem Lett· December 2005

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Novel caged fluorescein diphosphates as photoactivatable substrates for protein tyrosine phosphatases.
Qingping Wang, John Scheigetz, Bruno Roy, Chidambaram Ramachandran, Michael J Gresser

Biochim Biophys Acta· November 2002

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