Publications by authors named "Jonathan Blevitt"

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A Novel Small Molecule Allosteric Inhibitor of IL-17A from a DNA-Encoded Library.
Marcos E Milla, Jonathan M Blevitt, Steven D Goldberg, Anthony A Armstrong, Katherine Y Blain

ACS Med Chem Lett· November 2025

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High-throughput phenotypic screen identifies a new family of potent anti-amoebic compounds.
Conall Sauvey, Ittipat Meewan, Gretchen Ehrenkaufer, Jonathan Blevitt, Paul Jackson

PLoS One· May 2023

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Coupling to Gq Signaling Is Required for Cardioprotection by an Alpha-1A-Adrenergic Receptor Agonist.
Bat-Erdene Myagmar, Taylor Ismaili, Philip M Swigart, Anaha Raghunathan, Anthony J Baker, Jonathan M Blevitt

Circ Res· September 2019

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RORγt and RORα signature genes in human Th17 cells.
Glenda Castro, Xuejun Liu, Karen Ngo, Aimee De Leon-Tabaldo, Shanrong Zhao, Jonathan Blevitt

PLoS One· October 2017

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Structural Basis of Small-Molecule Aggregate Induced Inhibition of a Protein-Protein Interaction.
Jonathan M Blevitt, Michael D Hack, Krystal L Herman, Paul F Jackson, Paul J Krawczuk

J Med Chem· April 2017

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A Single Amino Acid Difference between Mouse and Human 5-Lipoxygenase Activating Protein (FLAP) Explains the Speciation and Differential Pharmacology of Novel FLAP Inhibitors.
Jonathan M Blevitt, Michael D Hack, Krystal Herman, Leon Chang, John M Keith

J Biol Chem· June 2016

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Polypharmacology of Small-Molecule Modulators of the 5-Lipoxygenase Activating Protein (FLAP) Observed via a High-throughput Lipidomics Platform.
Jiao Song, Xuejun Liu, Jian Zhu, Mandana Tootoonchi, John M Keith, Jonathan M Blevitt

J Biomol Screen· February 2016

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Phenotyping drug polypharmacology via eicosanoid profiling of blood.
Jiao Song, Xuejun Liu, Tadimeti S Rao, Leon Chang, Michael J Meehan, Jonathan M Blevitt

J Lipid Res· August 2015

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Oxysterols are agonist ligands of RORγt and drive Th17 cell differentiation.
Pejman Soroosh, Jiejun Wu, Xiaohua Xue, Jiao Song, Steven W Sutton, Jonathan Blevitt

Proc Natl Acad Sci U S A· August 2014

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A highly efficient, high-throughput lipidomics platform for the quantitative detection of eicosanoids in human whole blood.
Jiao Song, Xuejun Liu, Jiejun Wu, Michael J Meehan, Jonathan M Blevitt

Anal Biochem· February 2013

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Identification of benzofuran central cores for the inhibition of leukotriene A(4) hydrolase.
Wendy Eccles, Jonathan M Blevitt, Jamila N Booker, Christa C Chrovian, Shelby Crawford

Bioorg Med Chem Lett· February 2013

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Azabenzthiazole inhibitors of leukotriene A₄ hydrolase.
Virginia M Tanis, Genesis M Bacani, Jonathan M Blevitt, Christa C Chrovian, Shelby Crawford

Bioorg Med Chem Lett· December 2012

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A highly selective, orally bioavailable, vascular endothelial growth factor receptor-2 tyrosine kinase inhibitor has potent activity in vitro and in vivo.
Kenneth R LaMontagne, Jeannene Butler, Virna B Borowski, Angel R Fuentes-Pesquera, Jonathan M Blevitt

Angiogenesis· January 2010

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Phosphoinositide 3-kinase gamma (PI3Kgamma) inhibitors for the treatment of inflammation and autoimmune disease.
Jennifer D Venable, Michael K Ameriks, Jonathan M Blevitt, Robin L Thurmond, Wai-Ping Fung-Leung

Recent Pat Inflamm Allergy Drug Discov· January 2010

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Dual binding site inhibitors of B-RAF kinase.
Ronald L Wolin, Scott D Bembenek, Jianmei Wei, Shelby Crawford, Katherine Lundeen, Jonathan M Blevitt

Bioorg Med Chem Lett· May 2008

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A novel B-RAF inhibitor blocks interleukin-8 (IL-8) synthesis in human melanoma xenografts, revealing IL-8 as a potential pharmacodynamic biomarker.
Shelby Crawford, Daniel Belajic, Jianmei Wei, Jason P Riley, Paul J Dunford, Jonathan M Blevitt

Mol Cancer Ther· March 2008

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2-Aryl benzimidazoles featuring alkyl-linked pendant alcohols and amines as inhibitors of checkpoint kinase Chk2.
Danielle K Neff, Alice Lee-Dutra, Jonathan M Blevitt, Frank U Axe, Michael D Hack

Bioorg Med Chem Lett· December 2007

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