Publications by authors named "Jonathan D Finn"

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Ligase-mediated programmable genomic integration (L-PGI).
Angela X Nan, Michael Chickering, Christopher L Bartolome, Neeta Shadija, Dan Li, Jonathan D Finn

Nat Commun· December 2025

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Development of circular AAV cargos for targeted seamless insertion with large serine integrases.
Brett J G Estes, Nisha Gandhi, Jessica R Von Stetina, Dev Paudel, Angela X Nan, Jonathan D Finn

Mol Ther Methods Clin Dev· June 2025

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Unlocking the potential of iPSC-derived immune cells: engineering iNK and iT cells for cutting-edge immunotherapy.
Minggang Fang, Alexander Allen, Chong Luo, Jonathan D Finn

Front Immunol· September 2024

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Transfection reagent artefact likely accounts for some reports of extracellular vesicle function.
Russell E McConnell, Madeleine Youniss, Bhargavee Gnanasambandam, Palak Shah, Wei Zhang, Jonathan D Finn

J Extracell Vesicles· October 2022

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A versatile platform for generating engineered extracellular vesicles with defined therapeutic properties.
Kevin Dooley, Russell E McConnell, Ke Xu, Nuruddeen D Lewis, Sonya Haupt, Jonathan D Finn

Mol Ther· May 2021

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Evolutionary insights into coagulation factor IX Padua and other high-specific-activity variants.
Benjamin J Samelson-Jones, Jonathan D Finn, Leslie J Raffini, Elizabeth P Merricks, Rodney M Camire

Blood Adv· March 2021

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Timing of Intensive Immunosuppression Impacts Risk of Transgene Antibodies after AAV Gene Therapy in Nonhuman Primates.
Benjamin J Samelson-Jones, Jonathan D Finn, Patricia Favaro, J Fraser Wright, Valder R Arruda

Mol Ther Methods Clin Dev· June 2020

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Hyperactivity of factor IX Padua (R338L) depends on factor VIIIa cofactor activity.
Benjamin J Samelson-Jones, Jonathan D Finn, Lindsey A George, Rodney M Camire, Valder R Arruda

JCI Insight· June 2019

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A Single Administration of CRISPR/Cas9 Lipid Nanoparticles Achieves Robust and Persistent In Vivo Genome Editing.
Jonathan D Finn, Amy Rhoden Smith, Mihir C Patel, Lucinda Shaw, Madeleine R Youniss

Cell Rep· February 2018

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Empty Capsids and Macrophage Inhibition/Depletion Increase rAAV Transgene Expression in Joints of Both Healthy and Arthritic Mice.
Caroline J Aalbers, Niels Broekstra, Mariska van Geldorp, Emiel Kramer, Sofia Ramiro, Jonathan D Finn

Hum Gene Ther· February 2017

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AAV liver expression of FIX-Padua prevents and eradicates FIX inhibitor without increasing thrombogenicity in hemophilia B dogs and mice.
Julie M Crudele, Jonathan D Finn, Joshua I Siner, Nicholas B Martin, Glenn P Niemeyer

Blood· March 2015

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Characterization of naturally-occurring humoral immunity to AAV in sheep.
Joseph Tellez, Kim Van Vliet, Yu-Shan Tseng, Jonathan D Finn, Nick Tschernia

PLoS One· July 2014

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Modulation of CD8+ T cell responses to AAV vectors with IgG-derived MHC class II epitopes.
Daniel J Hui, Etiena Basner-Tschakarjan, Yifeng Chen, Robert J Davidson, George Buchlis, Jonathan D Finn

Mol Ther· September 2013

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Engineered AAV vector minimizes in vivo targeting of transduced hepatocytes by capsid-specific CD8+ T cells.
Ashley T Martino, Etiena Basner-Tschakarjan, David M Markusic, Jonathan D Finn, Christian Hinderer

Blood· March 2013

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The efficacy and the risk of immunogenicity of FIX Padua (R338L) in hemophilia B dogs treated by AAV muscle gene therapy.
Jonathan D Finn, Timothy C Nichols, Nikolaos Svoronos, Elizabeth P Merricks, Dwight A Bellenger

Blood· November 2012

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Safety of liver gene transfer following peripheral intravascular delivery of adeno-associated virus (AAV)-5 and AAV-6 in a large animal model.
Patricia Favaro, Jonathan D Finn, Joshua I Siner, J Fraser Wright, Katherine A High

Hum Gene Ther· July 2011

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In vivo genome editing restores haemostasis in a mouse model of haemophilia.
Hojun Li, Virginia Haurigot, Yannick Doyon, Tianjian Li, Sunnie Y Wong, Jonathan D Finn

Nature· June 2011

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CD8+ T-cell expansion and maintenance after recombinant adenovirus immunization rely upon cooperation between hematopoietic and nonhematopoietic antigen-presenting cells.
Jennifer D Bassett, Teng Chih Yang, Dannie Bernard, James B Millar, Stephanie L Swift, Jonathan D Finn

Blood· January 2011

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Eradication of neutralizing antibodies to factor VIII in canine hemophilia A after liver gene therapy.
Jonathan D Finn, Margareth C Ozelo, Denise E Sabatino, Helen W G Franck, Elizabeth P Merricks

Blood· December 2010

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Proteasome inhibitors decrease AAV2 capsid derived peptide epitope presentation on MHC class I following transduction.
Jonathan D Finn, Daniel Hui, Harre D Downey, Danielle Dunn, Gary C Pien

Mol Ther· January 2010

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Persistence of transgene expression influences CD8+ T-cell expansion and maintenance following immunization with recombinant adenovirus.
Jonathan D Finn, Jennifer Bassett, James B Millar, Natalie Grinshtein, Teng Chih Yang

J Virol· December 2009

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X-linked thrombophilia with a mutant factor IX (factor IX Padua).
Paolo Simioni, Daniela Tormene, Giulio Tognin, Sabrina Gavasso, Cristiana Bulato, Jonathan D Finn

N Engl J Med· October 2009

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Strategies to modulate immune responses: a new frontier for gene therapy.
Valder R Arruda, Patricia Favaro, Jonathan D Finn

Mol Ther· September 2009

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Capsid antigen presentation flags human hepatocytes for destruction after transduction by adeno-associated viral vectors.
Gary C Pien, Etiena Basner-Tschakarjan, Daniel J Hui, Ashley N Mentlik, Jonathan D Finn

J Clin Invest· June 2009

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Investigation of factors responsible for cell line cytoplasmic expression differences.
Jonathan D Finn, Tabitha Wong, Pieter R Cullis

BMC Mol Biol· May 2005

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