Publications by authors named "Jonathan P Lambert"

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MCU gain- and loss-of-function models define the duality of mitochondrial calcium uptake in heart failure.
Joanne F Garbincius, Timothy S Luongo, Jonathan P Lambert, Adam S Mangold, Emma K Murray

bioRxiv· April 2023

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Extra-cardiac BCAA catabolism lowers blood pressure and protects from heart failure.
Danielle Murashige, Jae Woo Jung, Michael D Neinast, Michael G Levin, Qingwei Chu, Jonathan P Lambert

Cell Metab· November 2022

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Altered composition of the mitochondrial Cauniporter in the failing human heart.
Melanie Paillard, Kai-Ting Huang, David Weaver, Jonathan P Lambert, John W Elrod

Cell Calcium· July 2022

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Abcg2-expressing side population cells contribute to cardiomyocyte renewal through fusion.
Amritha Yellamilli, Yi Ren, Ron T McElmurry, Jonathan P Lambert, Polina Gross

FASEB J· April 2020

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MCUB and mitochondrial calcium uptake - modeling, function, and therapeutic potential.
Jonathan P Lambert, Emma K Murray, John W Elrod

Expert Opin Ther Targets· March 2020

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MCUB Regulates the Molecular Composition of the Mitochondrial Calcium Uniporter Channel to Limit Mitochondrial Calcium Overload During Stress.
Jonathan P Lambert, Timothy S Luongo, Dhanendra Tomar, Pooja Jadiya, Erhe Gao

Circulation· November 2019

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Impaired mitochondrial calcium efflux contributes to disease progression in models of Alzheimer's disease.
Pooja Jadiya, Devin W Kolmetzky, Dhanendra Tomar, Antonio Di Meco, Alyssa A Lombardi, Jonathan P Lambert

Nat Commun· August 2019

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Spatial Separation of Mitochondrial Calcium Uptake and Extrusion for Energy-Efficient Mitochondrial Calcium Signaling in the Heart.
Sergio De La Fuente, Jonathan P Lambert, Zuzana Nichtova, Celia Fernandez Sanz, John W Elrod

Cell Rep· September 2018

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The mitochondrial Na/Ca exchanger is essential for Ca homeostasis and viability.
Timothy S Luongo, Jonathan P Lambert, Polina Gross, Mary Nwokedi, Alyssa A Lombardi

Nature· May 2017

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Exercise training provides cardioprotection by activating and coupling endothelial nitric oxide synthase a β-adrenergic receptor-AMP-activated protein kinase signaling pathway.
Larry A Barr, Jonathan P Lambert, Yuuki Shimizu, Lili A Barouch, Nawazish Naqvi

Med Gas Res· March 2017

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Angiotensin type 2-receptor (AT2R) activation induces hypotension in apolipoprotein E-deficient mice by activating peroxisome proliferator-activated receptor-γ.
Ming Li, Thor Tejada, Jonathan P Lambert, Chad K Nicholson, Eiji Yahiro

Am J Cardiovasc Dis· September 2016

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DJ-1 protects the heart against ischemia-reperfusion injury by regulating mitochondrial fission.
Yuuki Shimizu, Jonathan P Lambert, Chad K Nicholson, Joshua J Kim, David W Wolfson

J Mol Cell Cardiol· August 2016

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IGF-1 degradation by mouse mast cell protease 4 promotes cell death and adverse cardiac remodeling days after a myocardial infarction.
Thor Tejada, Lin Tan, Rebecca A Torres, John W Calvert, Jonathan P Lambert

Proc Natl Acad Sci U S A· June 2016

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Sodium Sulfide Attenuates Ischemic-Induced Heart Failure by Enhancing Proteasomal Function in an Nrf2-Dependent Manner.
Yuuki Shimizu, Chad K Nicholson, Jonathan P Lambert, Larry A Barr, Nicholas Kuek

Circ Heart Fail· April 2016

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The Mitochondrial Calcium Uniporter Matches Energetic Supply with Cardiac Workload during Stress and Modulates Permeability Transition.
Timothy S Luongo, Jonathan P Lambert, Ancai Yuan, Xueqian Zhang, Polina Gross

Cell Rep· July 2015

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Hydrogen sulfide attenuates high fat diet-induced cardiac dysfunction via the suppression of endoplasmic reticulum stress.
Larry A Barr, Yuuki Shimizu, Jonathan P Lambert, Chad K Nicholson, John W Calvert

Nitric Oxide· April 2015

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Hydrogen sulfide provides cardioprotection against myocardial/ischemia reperfusion injury in the diabetic state through the activation of the RISK pathway.
Jonathan P Lambert, Chad K Nicholson, Hena Amin, Sana Amin, John W Calvert

Med Gas Res· December 2014

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A proliferative burst during preadolescence establishes the final cardiomyocyte number.
Nawazish Naqvi, Ming Li, John W Calvert, Thor Tejada, Jonathan P Lambert

Cell· May 2014

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Chronic exercise downregulates myocardial myoglobin and attenuates nitrite reductase capacity during ischemia-reperfusion.
Chad K Nicholson, Jonathan P Lambert, Chi-Wing Chow, David J Lefer, John W Calvert

J Mol Cell Cardiol· November 2013

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Hydrogen sulfide preconditions the db/db diabetic mouse heart against ischemia-reperfusion injury by activating Nrf2 signaling in an Erk-dependent manner.
Bridgette F Peake, Chad K Nicholson, Jonathan P Lambert, Rebecca L Hood, Hena Amin

Am J Physiol Heart Circ Physiol· May 2013

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Thioredoxin 1 is essential for sodium sulfide-mediated cardioprotection in the setting of heart failure.
Chad K Nicholson, Jonathan P Lambert, Jeffery D Molkentin, Junichi Sadoshima, John W Calvert

Arterioscler Thromb Vasc Biol· April 2013

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