Publications by authors named "Jonathan RiosDoria"

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The FGFR inhibitor pemigatinib overcomes cancer drug resistance to KRAS G12C inhibitors in mesenchymal lung cancer.
Angela Abdollahi, Margaret Favata, Michael Weber, Valerie Roman, Rodrigo Hess

PLoS One· August 2025

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Characterization of INCB086550: A Potent and Novel Small-Molecule PD-L1 Inhibitor.
Holly K Koblish, Liangxing Wu, Liang-Chuan S Wang, Phillip C C Liu, Richard Wynn

Cancer Discov· June 2022

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A Potent and Selective Dual Inhibitor of AXL and MERTK Possesses Both Immunomodulatory and Tumor-Targeted Activity.
Jonathan Rios-Doria, Margaret Favata, Kerri Lasky, Patricia Feldman, Yvonne Lo

Front Oncol· December 2020

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Characterization of human cancer xenografts in humanized mice.
Jonathan Rios-Doria, Christina Stevens, Christopher Maddage, Kerri Lasky, Holly K Koblish

J Immunother Cancer· March 2020

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Evaluation of Pyrrolobenzodiazepine-Loaded Nanoparticles: A Targeted Drug Delivery Approach.
Puneet Tyagi, Sergei Pechenov, Jonathan RiosDoria, Luke Masterson, Niall J Dickinson

J Pharm Sci· April 2019

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Targeting ADAM17 inhibits human colorectal adenocarcinoma progression and tumor-initiating cell frequency.
Joseph Dosch, Elizabeth Ziemke, Shanshan Wan, Kathryn Luker, Theodore Welling

Oncotarget· September 2017

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Antibody-Drug Conjugates Bearing Pyrrolobenzodiazepine or Tubulysin Payloads Are Immunomodulatory and Synergize with Multiple Immunotherapies.
Jonathan Rios-Doria, Jay Harper, Raymond Rothstein, Leslie Wetzel, Jon Chesebrough

Cancer Res· May 2017

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Targeting CD73 in the tumor microenvironment with MEDI9447.
Carl M Hay, Erin Sult, Qihui Huang, Kathy Mulgrew, Stacy R Fuhrmann

Oncoimmunology· August 2016

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Lipid- and polyion complex-based micelles as agonist platforms for TNFR superfamily receptors.
Ryan N Gilbreth, Shabazz Novarra, Leslie Wetzel, Stelios Florinas, Horacio Cabral

J Control Release· July 2016

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Doxil synergizes with cancer immunotherapies to enhance antitumor responses in syngeneic mouse models.
Jonathan Rios-Doria, Nicholas Durham, Leslie Wetzel, Raymond Rothstein, Jon Chesebrough

Neoplasia· August 2015

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A Monoclonal Antibody to ADAM17 Inhibits Tumor Growth by Inhibiting EGFR and Non-EGFR-Mediated Pathways.
Jonathan Rios-Doria, Darrin Sabol, Jon Chesebrough, Dave Stewart, Linda Xu

Mol Cancer Ther· July 2015

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IT-141, a Polymer Micelle Encapsulating SN-38, Induces Tumor Regression in Multiple Colorectal Cancer Models.
Adam Carie, Jonathan Rios-Doria, Tara Costich, Brian Burke, Richard Slama

J Drug Deliv· August 2012

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A versatile polymer micelle drug delivery system for encapsulation and in vivo stabilization of hydrophobic anticancer drugs.
Jonathan Rios-Doria, Adam Carie, Tara Costich, Brian Burke, Habib Skaff

J Drug Deliv· August 2012

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Ectopic expression of histone H2AX mutants reveals a role for its post-translational modifications.
Jonathan Rios-Doria, Aneliya Velkova, Virna Dapic, José M Galán-Caridad, Vesna Dapic

Cancer Biol Ther· March 2009

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DNA damage response: determining the fate of phosphorylated histone H2AX.
Jonathan Rios-Doria, Alyson Fay, Aneliya Velkova, Alvaro N A Monteiro

Cancer Biol Ther· February 2006

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Truncated E-cadherin potentiates cell death in prostate epithelial cells.
Jonathan Rios-Doria, Mark L Day

Prostate· May 2005

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Cleavage of beta-catenin by calpain in prostate and mammary tumor cells.
Jonathan Rios-Doria, Rainer Kuefer, Stephen P Ethier, Mark L Day

Cancer Res· October 2004

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The role of calpain in the proteolytic cleavage of E-cadherin in prostate and mammary epithelial cells.
Jonathan Rios-Doria, Kathleen C Day, Rainer Kuefer, Michael G Rashid, Arul M Chinnaiyan

J Biol Chem· January 2003

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