Publications by authors named "Jonathan Sachs"

Claim this Profile
F
Fluorescence Lifetime-Based FRET Biosensors for Monitoring N Terminal Domain-Dependent Interactions of TDP-43 in Living Cells: A Novel Approach for ALS and FTD Drug Discovery.
Noah Nathan Kochen, Marguerite Murray, Sophia Zafari, Nagamani Vunnam, Elly E Liao, Jonathan N Sachs

ACS Chem Neurosci· July 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
E
Engineering Affibody Binders to Death Receptor 5 and Tumor Necrosis Factor Receptor 1 With Improved Stability.
Gregory H Nielsen, Jonathan N Sachs, Benjamin J Hackel

Biotechnol Bioeng· June 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
M
Multiplexed Dark FRET Biosensors: An accessible live-cell platform for target- and cell-specific monitoring of protein-protein interactions in 2D and 3D model systems.
Anthony Braun, Elly Liao, Nagamani Vunnam, Marguerite Murray, Jonathan Sachs

Res Sq· May 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
Post-translational modification sites are present in hydrophilic cavities of alpha-synuclein, tau, FUS, and TDP-43 fibrils: A molecular dynamics study.
Noah Nathan Kochen, Darren Seaney, Vivek Vasandani, Marguerite Murray, Anthony R Braun, Jonathan N Sachs

Proteins· July 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
N
Nimesulide, a COX-2 inhibitor, sensitizes pancreatic cancer cells to TRAIL-induced apoptosis by promoting DR5 clustering †.
Nagamani Vunnam, Malaney C Young, Elly E Liao, Chih Hung Lo, Evan Huber, Jonathan N Sachs

Cancer Biol Ther· December 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
Proteasomal Stimulation by MK886 and Its Derivatives Can Rescue Tau-Induced Neurite Pathology.
Elly E Liao, Mu Yang, Noah Nathan Kochen, Nagamani Vunnam, Anthony R Braun, Jonathan N Sachs

Mol Neurobiol· October 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
Advancements in a FRET Biosensor for Live-Cell Fluorescence-Lifetime High-Throughput Screening of Alpha-Synuclein.
Anthony R Braun, Noah Nathan Kochen, Samantha L Yuen, Elly E Liao, Razvan L Cornea, Jonathan N Sachs

ASN Neuro· July 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
H
Haboob Dust Storms and Motor Vehicle Collision-related Trauma in Phoenix, Arizona.
Michael B Henry, Michael Mozer, Jerome J Rogich, Kyle Farrell, Jonathan W Sachs

West J Emerg Med· July 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
Z
Zafirlukast Is a Promising Scaffold for Selectively Inhibiting TNFR1 Signaling.
Nagamani Vunnam, Mu Yang, Chih Hung Lo, Carolyn Paulson, William D Fiers, Jonathan N Sachs

ACS Bio Med Chem Au· June 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Discovery of a Non-competitive TNFR1 Antagonist Affibody with Picomolar Monovalent Potency That Does Not Affect TNFR2 Function.
Nagamani Vunnam, MaryJane Been, Evan Huber, Carolyn Paulson, Sophia Szymonski, Jonathan N Sachs

Mol Pharm· April 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
pH Effects Can Dominate Chemical Shift Perturbations in H,N-HSQC NMR Spectroscopy for Studies of Small Molecule/α-Synuclein Interactions.
Anil K Pandey, Caroline R Buchholz, Noah Nathan Kochen, William C K Pomerantz, Anthony R Braun, Jonathan N Sachs

ACS Chem Neurosci· February 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
Indirubin Inhibits TRAIL-Induced Activation of Death Receptor 5 in Jurkat Cells.
Malaney C Young, Nagamani Vunnam, Robyn T Rebbeck, Samantha L Yuen, David D Thomas, Jonathan N Sachs

Nat Prod Commun· January 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
B
Broad Tricyclic Ring Inhibitors Block SARS-CoV-2 Spike Function Required for Viral Entry.
Sneha Ratnapriya, Anthony R Braun, Héctor Cervera Benet, Danielle Carlson, Shilei Ding, Jonathan N Sachs

ACS Infect Dis· October 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
F
Fluorescence Lifetime Measurement of Prefibrillar Sickle Hemoglobin Oligomers as a Platform for Drug Discovery in Sickle Cell Disease.
Nagamani Vunnam, Scott Hansen, Dillon C Williams, MaryJane Olivia Been, Chih Hung Lo, Jonathan N Sachs

Biomacromolecules· September 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
Threonine Cavities Are Targetable Motifs That Control Alpha-Synuclein Fibril Growth.
Noah Nathan Kochen, Vivek Vasandani, Darren Seaney, Anil K Pandey, Michael A Walters, Jonathan N Sachs

ACS Chem Neurosci· September 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
R
Risk Stratification in Primary Care: Value-Based Contributions of Provider Adjudication.
Brian C Ricci, Jonathan Sachs, Konrad Dobbertin, Faiza Khan, David A Dorr

J Gen Intern Med· February 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
The quality of social determinants data in the electronic health record: a systematic review.
Lily A Cook, Jonathan Sachs, Nicole G Weiskopf

J Am Med Inform Assoc· December 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Disparities in telephone and video telehealth engagement during the COVID-19 pandemic.
Jonathan W Sachs, Peter Graven, Jeffrey A Gold, Steven Z Kassakian

JAMIA Open· July 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
Potent inhibitors of toxic alpha-synuclein identified via cellular time-resolved FRET biosensors.
Anthony R Braun, Elly E Liao, Mian Horvath, Prakriti Kalra, Karen Acosta, Jonathan N Sachs

NPJ Parkinsons Dis· June 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
F
Fluorescence-Based TNFR1 Biosensor for Monitoring Receptor Structural and Conformational Dynamics and Discovery of Small Molecule Modulators.
Chih Hung Lo, Tory M Schaaf, David D Thomas, Jonathan N Sachs

Methods Mol Biol· April 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
The role of wild-type tau in Alzheimer's disease and related tauopathies.
Chih Hung Lo, Jonathan N Sachs

J Life Sci (Westlake Village)· December 2020

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
N
Noncompetitive Allosteric Antagonism of Death Receptor 5 by a Synthetic Affibody Ligand.
Nagamani Vunnam, Sophia Szymonski, Petra Hirsova, Gregory J Gores, Jonathan N Sachs

Biochemistry· October 2020

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Discovery of Small Molecule Inhibitors of Huntingtin Exon 1 Aggregation by FRET-Based High-Throughput Screening in Living Cells.
Chih Hung Lo, Nitin K Pandey, Colin Kin-Wye Lim, Zhipeng Ding, Meixin Tao, Jonathan N Sachs

ACS Chem Neurosci· August 2020

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Conformational states of TNFR1 as a molecular switch for receptor function.
Chih Hung Lo, Evan C Huber, Jonathan N Sachs

Protein Sci· June 2020

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
H
How Do Ethanolamine Plasmalogens Contribute to Order and Structure of Neurological Membranes?
Ana West, Valeria Zoni, Walter E Teague, Alison N Leonard, Stefano Vanni, Jonathan N Sachs

J Phys Chem B· February 2020

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis