Publications by authors named "Jose Castell"

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Ontogeny of drug-induced fatty liver disease (DIFLD): from key initiating events to disease phenotypes.
Ernesto López-Pascual, Marta Moreno-Torres, Erika Moro, Anna Rapisarda, Rita Ortega-Vallbona, José V Castell

Arch Toxicol· December 2025

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Unravelling drug-induced hepatic steatosis: Clinical sub-phenotypes, outcome prediction, and identification of high-concern drugs and hazardous chemical attributes.
Marta Moreno-Torres, Ernesto López-Pascual, Erika Moro, Anna Rapisarda, Birgitte Lindeman, José V Castell

Biomed Pharmacother· October 2025

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Sinusoidal Obstruction Syndrome After Allogeneic Hematopoietic Cell Transplantation With Post-Transplant Cyclophosphamide.
Aitana Balaguer-Roselló, Juan Montoro, Marta Villalba, Patricia Lizama, Lisseth Torres, José Vicente Castell

Transplant Cell Ther· September 2025

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Surgical approach and postoperative outcomes after left pancreatectomy (Spandispan prospective project).
Belén Hernández-Roca, José M Ramia, Juli Busquets, Luis Secanella, Nuria Peláez, José Tomás Castell

Cir Esp (Engl Ed)· September 2025

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Effect of Volume on Postoperative Outcomes After Left Pancreatectomy: A Multicenter Prospective Snapshot Study (SPANDISPAN Project).
Daniel Aparicio-López, José M Ramia, Celia Villodre, Juan J Rubio-García, Belén Hernández, José T Castell

J Clin Med· August 2025

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The acyl glucuronide of 2-(4-diethylamino-2-hydroxybenzoyl)benzoic acid: Synthesis, structural assignment, occurrence as a human phase II metabolite of Uvinul® A Plus and acute aquatic toxicity.
María Payá-García, Gemma M Rodríguez-Muñiz, Marta Moreno-Torres, Erika Moro, Lucas Santos-Juanes, José V Castell

Chemosphere· May 2025

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A microRNA signature for valproate-induced steatosis in human hepatocytes and its application to predict fatty liver in paediatric epileptic patients on valproate therapy.
Polina Soluyanova, Marta Del Pozo, Erika Moro-Castaño, Ana V Marco-Hernández, José V Castell

Toxicology· December 2024

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Uncovering the toxicity mechanisms of a series of carboxylic acids in liver cells through computational and experimental approaches.
Rita Ortega-Vallbona, Rebeca Méndez, Laia Tolosa, Sylvia E Escher, José V Castell

Toxicology· May 2024

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Drug-Induced Fatty Liver Disease (DIFLD): A Comprehensive Analysis of Clinical, Biochemical, and Histopathological Data for Mechanisms Identification and Consistency with Current Adverse Outcome Pathways.
Ernesto López-Pascual, Ivan Rienda, Judith Perez-Rojas, Anna Rapisarda, Guillem Garcia-Llorens, José V Castell

Int J Mol Sci· May 2024

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Protectiveness of NAM-based hazard assessment - which testing scope is required?
Walter Zobl, Annette Bitsch, Jonathan Blum, Jan J W A Boei, Liliana Capinha, Jose Castell

ALTEX· April 2024

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Report of the First ONTOX Stakeholder Network Meeting: Digging Under the Surface of ONTOX Together With the Stakeholders.
Michael G Diemar, Mathieu Vinken, Marc Teunis, Cyrille A M Krul, Francois Busquet, Jose V Castell

Altern Lab Anim· March 2024

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Exploring Individual Variability in Drug-Induced Liver Injury (DILI) Responses through Metabolomic Analysis.
Marta Moreno-Torres, Guillermo Quintás, Teresa Martínez-Sena, Ramiro Jover, José V Castell

Int J Mol Sci· March 2024

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Cluster-Partial Least Squares (c-PLS) regression analysis: Application to miRNA and metabolomic data.
Julia Kuligowski, Álvaro Pérez-Rubio, Marta Moreno-Torres, Polina Soluyanova, Judith Pérez-Rojas, José V Castell

Anal Chim Acta· January 2024

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Automated Generation of hiPSC-Derived Hepatic Progeny by Cost-Efficient Compounds.
Gert Vanmarcke, Jonathan Sai-Hong Chui, Axelle Cooreman, Kristof De Vos, Lana Cleuren, José V Castell

Stem Cells· November 2023

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Comparing the direct assessment of steatosis in liver explants with mid- and near-infrared vibrational spectroscopy, prior to organ transplantation.
Iván Rienda, Erika Moro, Álvaro Pérez-Rubio, Ramón Trullenque-Juan, David Pérez-Guaita, Jose V Castell

Analyst· August 2023

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Gut Microbiota and Plasma Bile Acids Associated with Non-Alcoholic Fatty Liver Disease Resolution in Bariatric Surgery Patients.
Álvaro Pérez-Rubio, Polina Soluyanova, Erika Moro, Guillermo Quintás, Iván Rienda, José V Castell

Nutrients· July 2023

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Metabolomics-based strategy to assess drug hepatotoxicity and uncover the mechanisms of hepatotoxicity involved.
Teresa Martínez-Sena, Erika Moro, Marta Moreno-Torres, Guillermo Quintás, Jan Hengstler, José V Castell

Arch Toxicol· June 2023

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Enhancing the accuracy of mid-infrared spectroscopy-based liver steatosis quantification using digital image analysis as a reference.
Iván Rienda, Isabel Ten-Doménech, Erika Moro, Marta Moreno-Torres, Judith Pérez-Rojas, Jose V Castell

Analyst· June 2023

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The assessment of the potential hepatotoxicity of new drugs by metabolomics.
Guillermo Quintás, José V Castell, Marta Moreno-Torres

Front Pharmacol· May 2023

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A robust reprogramming strategy for generating hepatocyte-like cells usable in pharmaco-toxicological studies.
Guillem Garcia-Llorens, Teresa Martínez-Sena, Eugenia Pareja, Laia Tolosa, José V Castell

Stem Cell Res Ther· April 2023

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In vitro/in silico prediction of drug induced steatosis in relation to oral doses and blood concentrations by the Nile Red assay.
Tim Brecklinghaus, Wiebke Albrecht, Julia Duda, Franziska Kappenberg, Lisa Gründler, José V Castell

Toxicol Lett· September 2022

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Quantitative Prediction of Steatosis in Patients with Non-Alcoholic Fatty Liver by Means of Hepatic MicroRNAs Present in Serum and Correlating with Hepatic Fat.
Guillermo Quintás, Florian Caiment, Iván Rienda, Judith Pérez-Rojas, Eugenia Pareja, José V Castell

Int J Mol Sci· August 2022

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Modeling a Novel Variant of Glycogenosis IXa Using a Clonal Inducible Reprogramming System to Generate "Diseased" Hepatocytes for Accurate Diagnosis.
Guillem Garcia-Llorens, Sergi Lopez-Navarro, Teresa Jaijo, Jose V Castell, Roque Bort

J Pers Med· July 2022

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The Potential Role of Metabolomics in Drug-Induced Liver Injury (DILI) Assessment.
Marta Moreno-Torres, Guillermo Quintás, José V Castell

Metabolites· June 2022

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Methionine Cycle Rewiring by Targeting miR-873-5p Modulates Ammonia Metabolism to Protect the Liver from Acetaminophen.
Rubén Rodríguez-Agudo, Naroa Goikoetxea-Usandizaga, Marina Serrano-Maciá, Pablo Fernández-Tussy, David Fernández-Ramos, Jose Vicente Castell

Antioxidants (Basel)· April 2022

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