Publications by authors named "Joseph D Schonhoft"

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Genomic and Epigenomic ctDNA Profiling in Liquid Biopsies from Heavily Pretreated Patients with DNA Damage Response-Deficient Tumors.
Ian M Silverman, Joseph D Schonhoft, Benjamin Herzberg, Arielle Yablonovitch, Errin Lagow

Clin Cancer Res· October 2025

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Exceptional response to the ATR inhibitor, camonsertib, in a patient with ALT+ metastatic melanoma.
Natalie Y L Ngoi, Ian M Silverman, Adrienne Johnson, Chenfeng Meng, Joseph D Schonhoft

NPJ Precis Oncol· July 2025

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Discovery of RP-1664: A First-in-Class Orally Bioavailable, Selective PLK4 Inhibitor.
Frédéric Vallée, Matias Casás-Selves, Monica Bubenik, Martin Duplessis, Boubacar Sow, Joseph D Schonhoft

J Med Chem· June 2025

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Ataxia telangiectasia and Rad3-related (ATR) inhibitor camonsertib dose optimization in patients with biomarker-selected advanced solid tumors (TRESR study).
Elisa Fontana, Ezra Rosen, Elizabeth K Lee, Martin Højgaard, Niharika B Mettu, Joseph D Schonhoft

J Natl Cancer Inst· September 2024

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Post-therapy emergence of an NBN reversion mutation in a patient with pancreatic acinar cell carcinoma.
Meredith S Pelster, Ian M Silverman, Joseph D Schonhoft, Adrienne Johnson, Pier Selenica

NPJ Precis Oncol· April 2024

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Phase 1b study of enzalutamide plus CC-115, a dual mTORC1/2 and DNA-PK inhibitor, in men with metastatic castration-resistant prostate cancer (mCRPC).
Jimmy L Zhao, Emmanuel S Antonarakis, Heather H Cheng, Daniel J George, Rahul Aggarwal, Joseph D Schonhoft

Br J Cancer· January 2024

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Camonsertib in DNA damage response-deficient advanced solid tumors: phase 1 trial results.
Timothy A Yap, Elisa Fontana, Elizabeth K Lee, David R Spigel, Martin Højgaard, Joseph D Schonhoft

Nat Med· June 2023

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Analysis of BRCA2 Copy Number Loss and Genomic Instability in Circulating Tumor Cells from Patients with Metastatic Castration-resistant Prostate Cancer.
Ethan S Barnett, Nikolaus Schultz, Konrad H Stopsack, Ernest T Lam, Andrea Arfe, Joseph D Schonhoft

Eur Urol· February 2023

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Dynamic expression of Schlafen 11 (SLFN11) in circulating tumour cells as a liquid biomarker in small cell lung cancer.
Bingnan Zhang, C Allison Stewart, Qi Wang, Robert J Cardnell, Pedro Rocha, Joseph D Schonhoft

Br J Cancer· August 2022

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Author Correction: Circulating tumor cell heterogeneity in neuroendocrine prostate cancer by single cell copy number analysis.
Vincenza Conteduca, Sheng-Yu Ku, Luisa Fernandez, Angel Dago-Rodriquez, Jerry Lee, Joseph D Schonhoft

NPJ Precis Oncol· September 2021

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Circulating tumor cell heterogeneity in neuroendocrine prostate cancer by single cell copy number analysis.
Vincenza Conteduca, Sheng-Yu Ku, Luisa Fernandez, Angel Dago-Rodriquez, Jerry Lee, Joseph D Schonhoft

NPJ Precis Oncol· August 2021

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Circulating Tumor Cell Chromosomal Instability and Neuroendocrine Phenotype by Immunomorphology and Poor Outcomes in Men with mCRPC Treated with Abiraterone or Enzalutamide.
Landon C Brown, Susan Halabi, Joseph D Schonhoft, Qian Yang, Jun Luo

Clin Cancer Res· July 2021

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Circulating Tumor Cell Subtypes and T-cell Populations as Prognostic Biomarkers to Combination Immunotherapy in Patients with Metastatic Genitourinary Cancer.
Heather J Chalfin, Tiziano Pramparo, Amir Mortazavi, Scot A Niglio, Joseph D Schonhoft

Clin Cancer Res· March 2021

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Morphology-Predicted Large-Scale Transition Number in Circulating Tumor Cells Identifies a Chromosomal Instability Biomarker Associated with Poor Outcome in Castration-Resistant Prostate Cancer.
Joseph D Schonhoft, Jimmy L Zhao, Adam Jendrisak, Emily A Carbone, Ethan S Barnett

Cancer Res· November 2020

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Prospective Multicenter Study of Circulating Tumor Cell AR-V7 and Taxane Versus Hormonal Treatment Outcomes in Metastatic Castration-Resistant Prostate Cancer.
Andrew J Armstrong, Jun Luo, David M Nanus, Paraskevi Giannakakou, Russell Z Szmulewitz, Joseph D Schonhoft

JCO Precis Oncol· October 2020

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Development of an immunofluorescent AR-V7 circulating tumor cell assay - A blood-based test for men with metastatic prostate cancer.
David Lu, Rachel Krupa, Melissa Harvey, Ryon P Graf, Nicole Schreiber, Joseph D Schonhoft

J Circ Biomark· October 2020

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Identification and Characterization of Circulating Tumor Cells in Men Who have Undergone Prostatectomy for Clinically Localized, High Risk Prostate Cancer.
Terence W Friedlander, Christopher Welty, Archana Anantharaman, Joseph D Schonhoft, Adam Jendrisak

J Urol· October 2019

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Circulating Tumor Cells as a Predictor of Treatment Response in Clinically Localized Prostate Cancer.
Simpa S Salami, Udit Singhal, Daniel E Spratt, Ganesh S Palapattu, Brent K Hollenbeck, Joseph D Schonhoft

JCO Precis Oncol· May 2019

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Disordered N-Terminal Domain of Human Uracil DNA Glycosylase (hUNG2) Enhances DNA Translocation.
Gaddiel Rodriguez, Alexandre Esadze, Brian P Weiser, Joseph D Schonhoft, Philip A Cole

ACS Chem Biol· September 2017

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Peptide probes detect misfolded transthyretin oligomers in plasma of hereditary amyloidosis patients.
Joseph D Schonhoft, Cecilia Monteiro, Lars Plate, Yvonne S Eisele, John M Kelly

Sci Transl Med· September 2017

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The endoplasmic reticulum HSP40 co-chaperone ERdj3/DNAJB11 assembles and functions as a tetramer.
Kai-Chun Chen, Song Qu, Saikat Chowdhury, Isabelle C Noxon, Joseph D Schonhoft

EMBO J· August 2017

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Molecular crowding enhances facilitated diffusion of two human DNA glycosylases.
Shannen L Cravens, Joseph D Schonhoft, Meng M Rowland, Alyssa A Rodriguez, Breeana G Anderson

Nucleic Acids Res· April 2015

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Microscopic mechanism of DNA damage searching by hOGG1.
Meng M Rowland, Joseph D Schonhoft, Paige L McKibbin, Sheila S David, James T Stivers

Nucleic Acids Res· August 2014

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Correction to DNA translocation by human uracil DNA glycosylase: role of DNA phosphate charge.
Joseph D Schonhoft, John G Kosowicz, James T Stivers

Biochemistry· November 2013

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DNA translocation by human uracil DNA glycosylase: role of DNA phosphate charge.
Joseph D Schonhoft, John G Kosowicz, James T Stivers

Biochemistry· April 2013

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