Publications by authors named "Joseph Davide"

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Development of process analytical tools for rapid monitoring of live virus vaccines in manufacturing.
Sijia Yi, Reilly McCracken, Joseph Davide, Daniel Ryan Salovich, Travis Whitmer

Sci Rep· September 2022

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Flow virometry for process monitoring of live virus vaccines-lessons learned from ERVEBO.
Geoffri Ricci, Kevin Minsker, Austin Kapish, James Osborn, Sha Ha, Joseph Davide

Sci Rep· April 2021

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Intratracheal Administration of siRNA Triggers mRNA Silencing in the Lung to Modulate T Cell Immune Response and Lung Inflammation.
Bruce Ng, Tanesha Cash-Mason, Yi Wang, Jessica Seitzer, Julja Burchard, Joseph Davide

Mol Ther Nucleic Acids· June 2019

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Visualization of mitotic arrest of cell cycle with bioluminescence imaging in living animals.
Guo-Jun Zhang, Tsing-Bau Chen, Joseph Davide, Weikang Tao, Amy Vanko

Mol Imaging Biol· August 2013

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Quantification of Cy-5 siRNA signal in the intra-vital multi-photon microscopy images.
Antong Chen, Belma Dogdas, Saurin Mehta, Kathleen Haskell, Bruce Ng, Joseph Davide

Annu Int Conf IEEE Eng Med Biol Soc· July 2013

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Mechanistically probing lipid-siRNA nanoparticle-associated toxicities identifies Jak inhibitors effective in mitigating multifaceted toxic responses.
Weikang Tao, Xianzhi Mao, Joseph P Davide, Bruce Ng, Mingmei Cai

Mol Ther· March 2011

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Noninvasive imaging of lipid nanoparticle-mediated systemic delivery of small-interfering RNA to the liver.
Weikang Tao, Joseph P Davide, Mingmei Cai, Guo-Jun Zhang, Victoria J South

Mol Ther· September 2010

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Evaluation of efficacy, biodistribution, and inflammation for a potent siRNA nanoparticle: effect of dexamethasone co-treatment.
Marc T Abrams, Martin L Koser, Jessica Seitzer, Stephanie C Williams, Martha A DiPietro, Joseph P Davide

Mol Ther· January 2010

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Kinesin spindle protein (KSP) inhibitors. 9. Discovery of (2S)-4-(2,5-difluorophenyl)-n-[(3R,4S)-3-fluoro-1-methylpiperidin-4-yl]-2-(hydroxymethyl)-N-methyl-2-phenyl-2,5-dihydro-1H-pyrrole-1-carboxamide (MK-0731) for the treatment of taxane-refractory cancer.
Christopher D Cox, Paul J Coleman, Michael J Breslin, David B Whitman, Robert M Garbaccio, Joseph P Davide

J Med Chem· July 2008

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Kinesin spindle protein (KSP) inhibitors. Part 6: Design and synthesis of 3,5-diaryl-4,5-dihydropyrazole amides as potent inhibitors of the mitotic kinesin KSP.
Paul J Coleman, John D Schreier, Christopher D Cox, Mark E Fraley, Robert M Garbaccio, Joseph P Davide

Bioorg Med Chem Lett· October 2007

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Kinesin spindle protein (KSP) inhibitors. Part 8: Design and synthesis of 1,4-diaryl-4,5-dihydropyrazoles as potent inhibitors of the mitotic kinesin KSP.
Anthony J Roecker, Paul J Coleman, Swati P Mercer, John D Schreier, Carolyn A Buser, Joseph P Davide

Bioorg Med Chem Lett· October 2007

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Kinesin spindle protein (KSP) inhibitors. Part 7: Design and synthesis of 3,3-disubstituted dihydropyrazolobenzoxazines as potent inhibitors of the mitotic kinesin KSP.
Robert M Garbaccio, Edward S Tasber, Lou Anne Neilson, Paul J Coleman, Mark E Fraley, Joseph P Davide

Bioorg Med Chem Lett· October 2007

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An inhibitor of the kinesin spindle protein activates the intrinsic apoptotic pathway independently of p53 and de novo protein synthesis.
Weikang Tao, Victoria J South, Ronald E Diehl, Joseph P Davide, Laura Sepp-Lorenzino

Mol Cell Biol· January 2007

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Induction of apoptosis by an inhibitor of the mitotic kinesin KSP requires both activation of the spindle assembly checkpoint and mitotic slippage.
Weikang Tao, Victoria J South, Yun Zhang, Joseph P Davide, Linda Farrell

Cancer Cell· July 2005

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Macrocyclic piperazinones as potent dual inhibitors of farnesyltransferase and geranylgeranyltransferase-I.
Christopher J Dinsmore, C Blair Zartman, Jeffrey M Bergman, Marc T Abrams, Carolyn A Buser, Joseph P Davide

Bioorg Med Chem Lett· February 2004

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A cell-based radioligand binding assay for farnesyl: protein transferase inhibitors.
Robert B Lobell, Joseph P Davide, Nancy E Kohl, H Donald Burns, Wai-Si Eng

J Biomol Screen· August 2003

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The synthesis and biological evaluation of a series of potent dual inhibitors of farnesyl and geranyl-Geranyl protein transferases.
Thomas J Tucker, Marc T Abrams, Carolyn A Buser, Joseph P Davide, Michelle Ellis-Hutchings

Bioorg Med Chem Lett· August 2002

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Preclinical and clinical pharmacodynamic assessment of L-778,123, a dual inhibitor of farnesyl:protein transferase and geranylgeranyl:protein transferase type-I.
Robert B Lobell, Dongming Liu, Carolyn A Buser, Joseph P Davide, Elizabeth DePuy

Mol Cancer Ther· July 2002

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3-Aminopyrrolidinone farnesyltransferase inhibitors: design of macrocyclic compounds with improved pharmacokinetics and excellent cell potency.
Ian M Bell, Steven N Gallicchio, Marc Abrams, Lorena S Beese, Douglas C Beshore, Joseph Davide

J Med Chem· June 2002

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Potent inhibitors of farnesyltransferase and geranylgeranyltransferase-I.
Diem N Nguyen, Craig A Stump, Eileen S Walsh, Christine Fernandes, Joseph P Davide

Bioorg Med Chem Lett· May 2002

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