Publications by authors named "Joseph Guarnieri"

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Partial restoration of mitochondrial dysfunction by AAV-Ant1 protects from dilated cardiomyopathy in Ant1 plus mtDNA mutant mice.
Alessia Angelin, Kierstin Keller, Peiran Lu, Joseph W Guarnieri, Gabrielle A Widjaja

Nat Commun· December 2025

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Importance of De Novo Gene Evolution to Emerging Viral Threats: The ORF10 Strain-Restricted Orphan Gene of SARS-CoV-2 Promotes Pathogenesis.
Jeffrey A Haltom, Nidia S Trovao, Joseph W Guarnieri, Vincent Pan, Urminder Singh

Mol Biol Evol· October 2025

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Respiratory viral infections awaken metastatic breast cancer cells in lungs.
Shi B Chia, Bryan J Johnson, Junxiao Hu, Felipe Valença-Pereira, Marc Chadeau-Hyam, Joseph W Guarnieri

Nature· September 2025

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Obesity-Induced Metabolic Priming Exacerbates SARS-CoV-2 Inflammation.
Gustavo Gastão Davanzo, Bianca Gazieri Castelucci, Gabriela Fabiano de Souza, Stéfanie Primon Muraro, Larissa Menezes Dos Reis, Joseph W Guarnieri

Immunology· July 2025

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ZNFX1 Functions as a Master Regulator of Epigenetically Induced Pathogen Mimicry and Inflammasome Signaling in Cancer.
Lora Stojanovic, Rachel Abbotts, Kaushelendra Tripathi, Collin M Coon, Saranya Rajendran, Joseph W Guarnieri

Cancer Res· April 2025

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Mitochondrial hyperactivity and reactive oxygen species drive innate immunity to the yellow fever virus-17D live-attenuated vaccine.
Samantha G Muccilli, Benjamin Schwarz, Byron Shue, Forrest Jessop, Jeffrey G Shannon, Joseph W Guarnieri

PLoS Pathog· April 2025

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Lethal COVID-19 associates with RAAS-induced inflammation for multiple organ damage including mediastinal lymph nodes.
Michael J Topper, Joseph W Guarnieri, Jeffrey A Haltom, Amy Chadburn, Henry Cope

Proc Natl Acad Sci U S A· December 2024

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Methodologies for Mitochondrial Omic Profiling During Spaceflight.
Joseph W Guarnieri, JangKeun Kim, Douglas C Wallace, Christopher E Mason, Masafumi Muratani

Methods Mol Biol· November 2024

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To boldly go where no microRNAs have gone before: spaceflight impact on risk for small-for-gestational-age infants.
Giada Corti, JangKeun Kim, Francisco J Enguita, Joseph W Guarnieri, Lawrence I Grossman

Commun Biol· October 2024

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Author Correction: To boldly go where no microRNAs have gone before: spaceflight impact on risk for small-for-gestational-age infants.
Giada Corti, JangKeun Kim, Francisco J Enguita, Joseph W Guarnieri, Lawrence I Grossman

Commun Biol· October 2024

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PET Imaging with [F]ROStrace Detects Oxidative Stress and Predicts Parkinson's Disease Progression in Mice.
Yi Zhu, Neha Kohli, Anthony Young, Malkah Sheldon, Jani Coni, Joseph W Guarnieri

Antioxidants (Basel)· October 2024

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ZNFX1 is a Novel Master Regulator in Epigenetically-induced Pathogen Mimicry and Inflammasome Signaling in Cancer.
Lora Stojanovic, Rachel Abbotts, Kaushlendra Tripathi, Collin M Coon, Saranya Rajendran, Joseph W Guarnieri

bioRxiv· October 2024

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Mitochondrial Hyperactivity and Reactive Oxygen Species Drive Innate Immunity to the Yellow Fever Virus-17D Live-Attenuated Vaccine.
Samantha G Muccilli, Benjamin Schwarz, Forrest Jessop, Jeffrey G Shannon, Eric Bohrnsen, Joseph W Guarnieri

bioRxiv· September 2024

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Mitochondrial antioxidants abate SARS-COV-2 pathology in mice.
Joseph W Guarnieri, Timothy Lie, Yentli E Soto Albrecht, Peter Hewin, Kellie A Jurado

Proc Natl Acad Sci U S A· July 2024

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SARS-CoV-2 mitochondrial metabolic and epigenomic reprogramming in COVID-19.
Joseph W Guarnieri, Jeffrey A Haltom, Yentli E Soto Albrecht, Timothy Lie, Arnold Z Olali

Pharmacol Res· June 2024

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Secretome profiling reveals acute changes in oxidative stress, brain homeostasis, and coagulation following short-duration spaceflight.
Nadia Houerbi, JangKeun Kim, Eliah G Overbey, Richa Batra, Annalise Schweickart, Joseph W Guarnieri

Nat Commun· June 2024

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Space radiation damage rescued by inhibition of key spaceflight associated miRNAs.
J Tyson McDonald, JangKeun Kim, Lily Farmerie, Meghan L Johnson, Nidia S Trovao, Joseph W Guarnieri

Nat Commun· June 2024

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A comprehensive SARS-CoV-2 and COVID-19 review, Part 2: host extracellular to systemic effects of SARS-CoV-2 infection.
S Anand Narayanan, David A Jamison, Joseph W Guarnieri, Victoria Zaksas, Michael Topper

Eur J Hum Genet· January 2024

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SARS-CoV-2 Orphan Gene ORF10 Contributes to More Severe COVID-19 Disease.
Jeffrey Haltom, Nidia S Trovao, Joseph Guarnieri, Pan Vincent, Urminder Singh

medRxiv· November 2023

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Core mitochondrial genes are down-regulated during SARS-CoV-2 infection of rodent and human hosts.
Joseph W Guarnieri, Joseph M Dybas, Hossein Fazelinia, Man S Kim, Justin Frere

Sci Transl Med· August 2023

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SARS-COV-2 viroporins activate the NLRP3-inflammasome by the mitochondrial permeability transition pore.
Joseph W Guarnieri, Alessia Angelin, Deborah G Murdock, Patrick Schaefer, Prasanth Portluri

Front Immunol· March 2023

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A comprehensive SARS-CoV-2 and COVID-19 review, Part 1: Intracellular overdrive for SARS-CoV-2 infection.
David A Jamison, S Anand Narayanan, Nídia S Trovão, Joseph W Guarnieri, Michael J Topper

Eur J Hum Genet· August 2022

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TARGETED DOWN REGULATION OF CORE MITOCHONDRIAL GENES DURING SARS-COV-2 INFECTION.
Joseph W Guarnieri, Joseph M Dybas, Hossein Fazelinia, Man S Kim, Justin Frere

bioRxiv· February 2022

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Role of miR-2392 in driving SARS-CoV-2 infection.
J Tyson McDonald, Francisco J Enguita, Deanne Taylor, Robert J Griffin, Waldemar Priebe, Joseph W Guarnieri

Cell Rep· October 2021

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The Great Deceiver: miR-2392's Hidden Role in Driving SARS-CoV-2 Infection.
J Tyson McDonald, Francisco Javier Enguita, Deanne Taylor, Robert J Griffin, Waldemar Priebe, Joseph W Guarnieri

bioRxiv· August 2021

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