Publications by authors named "Joseph Lehar"

Claim this Profile
C
Current Status and Future Directions: The Application of Artificial Intelligence/Machine Learning for Precision Medicine.
Kunal Naik, Rahul K Goyal, Luca Foschini, Choi Wai Chak, Christian Thielscher

Clin Pharmacol Ther· April 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
U
Using a wearable patch to develop a digital monitoring biomarker of inflammation in response to LPS challenge.
Stefan Avey, Meenakshi Chatterjee, Nikolay V Manyakov, Philip Cooper, Nina Sabins, Joseph Lehar

Clin Transl Sci· February 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
Q
Quantifying neurologic disease using biosensor measurements in-clinic and in free-living settings in multiple sclerosis.
Tanuja Chitnis, Bonnie I Glanz, Cindy Gonzalez, Brian C Healy, Taylor J Saraceno

NPJ Digit Med· December 2019

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
CANDI: an R package and Shiny app for annotating radiographs and evaluating computer-aided diagnosis.
Marcus A Badgeley, Manway Liu, Benjamin S Glicksberg, Mark Shervey, John Zech, Joseph Lehar

Bioinformatics· May 2019

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
N
Next-generation characterization of the Cancer Cell Line Encyclopedia.
Mahmoud Ghandi, Franklin W Huang, Judit Jané-Valbuena, Gregory V Kryukov, Christopher C Lo, Joseph Lehar

Nature· May 2019

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
Addendum: The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Jordi Barretina, Giordano Caponigro, Nicolas Stransky, Kavitha Venkatesan, Adam A Margolin

Nature· January 2019

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
Automated deep-neural-network surveillance of cranial images for acute neurologic events.
Joseph J Titano, Marcus Badgeley, Javin Schefflein, Margaret Pain, Andres Su, Joseph Lehar

Nat Med· September 2018

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
N
Natural Language-based Machine Learning Models for the Annotation of Clinical Radiology Reports.
John Zech, Margaret Pain, Joseph Titano, Marcus Badgeley, Javin Schefflein, Joseph Lehar

Radiology· May 2018

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
R
Resistance mechanisms to TP53-MDM2 inhibition identified by in vivo piggyBac transposon mutagenesis screen in an Arf mouse model.
Emilie A Chapeau, Agnieszka Gembarska, Eric Y Durand, Emeline Mandon, Claire Estadieu, Joseph Lehar

Proc Natl Acad Sci U S A· March 2017

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
H
High-Order Drug Combinations Are Required to Effectively Kill Colorectal Cancer Cells.
Thomas Horn, Stéphane Ferretti, Nicolas Ebel, Angela Tam, Samuel Ho

Cancer Res· December 2016

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Simulating Serial-Target Antibacterial Drug Synergies Using Flux Balance Analysis.
Andrew S Krueger, Christian Munck, Gautam Dantas, George M Church, James Galagan

PLoS One· July 2016

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
G
Gene Expression Ratios Lead to Accurate and Translatable Predictors of DR5 Agonism across Multiple Tumor Lineages.
Anupama Reddy, Joseph D Growney, Nick S Wilson, Caroline M Emery, Jennifer A Johnson

PLoS One· May 2016

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Correction: Gene Expression Ratios Lead to Accurate and Translatable Predictors of DR5 Agonism across Multiple Tumor Lineages.
Anupama Reddy, Joseph D Growney, Nick S Wilson, Caroline M Emery, Jennifer A Johnson

PLoS One· April 2016

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
A meta-analysis approach for characterizing pan-cancer mechanisms of drug sensitivity in cell lines.
Kendric Wang, Raunak Shrestha, Alexander W Wyatt, Anupama Reddy, Joseph Lehár

PLoS One· November 2015

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
H
High-throughput screening using patient-derived tumor xenografts to predict clinical trial drug response.
Hui Gao, Joshua M Korn, Stéphane Ferretti, John E Monahan, Youzhen Wang, Joseph Lehar

Nat Med· November 2015

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
A screen of approved drugs and molecular probes identifies therapeutics with anti-Ebola virus activity.
Lisa M Johansen, Lisa Evans DeWald, Charles J Shoemaker, Benjamin G Hoffstrom, Calli M Lear-Rooney

Sci Transl Med· June 2015

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
CDK 4/6 inhibitors sensitize PIK3CA mutant breast cancer to PI3K inhibitors.
Sadhna R Vora, Dejan Juric, Nayoon Kim, Mari Mino-Kenudson, Tiffany Huynh, Joseph Lehar

Cancer Cell· July 2014

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
Inhibiting Tankyrases sensitizes KRAS-mutant cancer cells to MEK inhibitors via FGFR2 feedback signaling.
Marie Schoumacher, Kristen E Hurov, Joseph Lehár, Yan Yan-Neale, Yuji Mishina

Cancer Res· June 2014

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Characterization of the novel and specific PI3Kα inhibitor NVP-BYL719 and development of the patient stratification strategy for clinical trials.
Christine Fritsch, Alan Huang, Christian Chatenay-Rivauday, Christian Schnell, Anupama Reddy, Joseph Lehar

Mol Cancer Ther· May 2014

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
F
FDA-approved selective estrogen receptor modulators inhibit Ebola virus infection.
Lisa M Johansen, Jennifer M Brannan, Sue E Delos, Charles J Shoemaker, Andrea Stossel

Sci Transl Med· June 2013

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
R
RAD001 enhances the potency of BEZ235 to inhibit mTOR signaling and tumor growth.
Beat Nyfeler, Yan Chen, Xiaoyan Li, Maria Pinzon-Ortiz, Zuncai Wang

PLoS One· May 2013

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Jordi Barretina, Giordano Caponigro, Nicolas Stransky, Kavitha Venkatesan, Adam A Margolin

Nature· March 2012

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
K
Knocking out multigene redundancies via cycles of sexual assortment and fluorescence selection.
Yo Suzuki, Robert P St Onge, Ramamurthy Mani, Oliver D King, Adrian Heilbut

Nat Methods· February 2011

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
Identification of synergistic combinations of F508del cystic fibrosis transmembrane conductance regulator (CFTR) modulators.
Stephen Lin, Jinliang Sui, Shakira Cotard, Brenda Fung, Jennifer Andersen, Joseph Lehar

Assay Drug Dev Technol· December 2010

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
R
Recurrent, robust and scalable patterns underlie human approach and avoidance.
Byoung Woo Kim, David N Kennedy, Joseph Lehár, Myung Joo Lee, Anne J Blood

PLoS One· May 2010

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis