Publications by authors named "Yan Yan-Neale"

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Toward the Validation of Maternal Embryonic Leucine Zipper Kinase: Discovery, Optimization of Highly Potent and Selective Inhibitors, and Preliminary Biology Insight.
B Barry Touré, John Giraldes, Troy Smith, Elizabeth R Sprague, Yaping Wang, Yan Yan-Neale

J Med Chem· May 2016

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Disordered methionine metabolism in MTAP/CDKN2A-deleted cancers leads to dependence on PRMT5.
Konstantinos J Mavrakis, E Robert McDonald, Michael R Schlabach, Eric Billy, Gregory R Hoffman, Yan Yan-Neale

Science· March 2016

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Inhibiting Tankyrases sensitizes KRAS-mutant cancer cells to MEK inhibitors via FGFR2 feedback signaling.
Marie Schoumacher, Kristen E Hurov, Joseph Lehár, Yan Yan-Neale, Yuji Mishina

Cancer Res· June 2014

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The design, synthesis and structure-activity relationships of novel isoindoline-based histone deacetylase inhibitors.
Michael Shultz, Jianmei Fan, Christine Chen, Young Shin Cho, Nicole Davis, Yan Yan-Neale

Bioorg Med Chem Lett· August 2011

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Optimization of the in vitro cardiac safety of hydroxamate-based histone deacetylase inhibitors.
Michael D Shultz, Xueying Cao, Christine H Chen, Young Shin Cho, Nicole R Davis, Yan Yan-Neale

J Med Chem· July 2011

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Conformational refinement of hydroxamate-based histone deacetylase inhibitors and exploration of 3-piperidin-3-ylindole analogues of dacinostat (LAQ824).
Young Shin Cho, Lewis Whitehead, Jianke Li, Christine H-T Chen, Lei Jiang, Yan Yan-Neale

J Med Chem· April 2010

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Activation of mitochondrial pathway is crucial for tumor selective induction of apoptosis by LAQ824.
Shaowen Wang, Yan Yan-Neale, Richard Cai, Irina Alimov, Dalia Cohen

Cell Cycle· August 2006

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Transcription regulation by histone deacetylases.
Shaowen Wang, Yan Yan-Neale, Marija Zeremski, Dalia Cohen

Novartis Found Symp· June 2004

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Histone deacetylase 1 represses the small GTPase RhoB expression in human nonsmall lung carcinoma cell line.
Shaowen Wang, Yan Yan-Neale, Denise Fischer, Marija Zeremski, Richard Cai

Oncogene· September 2003

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Rapid expression cloning of receptors using epitope-tagged ligands and high-speed cell sorting.
Anna S Robeva, Yan Yan-Neale, Patricia Burfeind, Dale L Bodian, Gung-Wei Chirn

Cytometry A· February 2003

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Gene expression profiling of epothilone A-resistant cells.
Peter Atadja, Yan Yan-Neale, Harry Towbin, Frank Buxton, Dalia Cohen

Novartis Found Symp· December 2002

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