Publications by authors named "Joshua D Leach"

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MNK Inhibition Sensitizes -Mutant Colorectal Cancer to mTORC1 Inhibition by Reducing eIF4E Phosphorylation and c-MYC Expression.
John R P Knight, Constantinos Alexandrou, George L Skalka, Nikola Vlahov, Kathryn Pennel, Joshua D Leach

Cancer Discov· May 2021

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Epithelial NOTCH Signaling Rewires the Tumor Microenvironment of Colorectal Cancer to Drive Poor-Prognosis Subtypes and Metastasis.
Rene Jackstadt, Sander R van Hooff, Joshua D Leach, Xabier Cortes-Lavaud, Jeroen O Lohuis

Cancer Cell· September 2019

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Author Correction: Loss of BCL9/9l suppresses Wnt driven tumourigenesis in models that recapitulate human cancer.
David M Gay, Rachel A Ridgway, Miryam Müller, Michael C Hodder, Ann Hedley, Joshua D Leach

Nat Commun· March 2019

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Loss of BCL9/9l suppresses Wnt driven tumourigenesis in models that recapitulate human cancer.
David M Gay, Rachel A Ridgway, Miryam Müller, Michael C Hodder, Ann Hedley, Joshua D Leach

Nat Commun· February 2019

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CXCR2 inhibition suppresses acute and chronic pancreatic inflammation.
Colin W Steele, Saadia A Karim, Mona Foth, Loveena Rishi, Joshua D G Leach

J Pathol· September 2015

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What Is Your Neurologic Diagnosis? Suspected immune-mediated thrombocytopenia with secondary spinal cord hemorrhage.
Julien Guevar, Rodrigo Gutierrez-Quintana, Joshua D G Leach, Jacques Penderis

J Am Vet Med Assoc· September 2015

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Mitotic Stress Is an Integral Part of the Oncogene-Induced Senescence Program that Promotes Multinucleation and Cell Cycle Arrest.
Dina Dikovskaya, John J Cole, Susan M Mason, Colin Nixon, Saadia A Karim, Joshua D G Leach

Cell Rep· September 2015

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Fumarate induces redox-dependent senescence by modifying glutathione metabolism.
Liang Zheng, Simone Cardaci, Livnat Jerby, Elaine D MacKenzie, Marco Sciacovelli, Joshua D G Leach

Nat Commun· January 2015

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