Publications by authors named "Judith C Fleming"

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Delayed and Prolonged Histone Hyperacetylation with a Selective HDAC1/HDAC2 Inhibitor.
Joey L Methot, Dawn Mampreian Hoffman, David J Witter, Matthew G Stanton, Paul Harrington, Judith C Fleming

ACS Med Chem Lett· April 2014

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Parallel medicinal chemistry approaches to selective HDAC1/HDAC2 inhibitor (SHI-1:2) optimization.
Solomon D Kattar, Laura M Surdi, Anna Zabierek, Joey L Methot, Richard E Middleton, Judith C Fleming

Bioorg Med Chem Lett· February 2009

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SAR profiles of spirocyclic nicotinamide derived selective HDAC1/HDAC2 inhibitors (SHI-1:2).
Joey L Methot, Christopher L Hamblett, Dawn M Mampreian, Joon Jung, Andreas Harsch, Judith C Fleming

Bioorg Med Chem Lett· December 2008

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Phenylglycine and phenylalanine derivatives as potent and selective HDAC1 inhibitors (SHI-1).
Kevin J Wilson, David J Witter, Jonathan B Grimm, Phieng Siliphaivanh, Karin M Otte, Judith C Fleming

Bioorg Med Chem Lett· March 2008

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Amino acid derivatives as histone deacetylase inhibitors.
Jed L Hubbs, Hua Zhou, Astrid M Kral, Judith C Fleming, William K Dahlberg

Bioorg Med Chem Lett· January 2008

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Optimization of biaryl Selective HDAC1&2 Inhibitors (SHI-1:2).
David J Witter, Paul Harrington, Kevin J Wilson, Melissa Chenard, Judith C Fleming

Bioorg Med Chem Lett· January 2008

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The discovery of 6-amino nicotinamides as potent and selective histone deacetylase inhibitors.
Christopher L Hamblett, Joey L Methot, Dawn M Mampreian, David L Sloman, Matthew G Stanton, Judith C Fleming

Bioorg Med Chem Lett· October 2007

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Design of novel histone deacetylase inhibitors.
Phieng Siliphaivanh, Paul Harrington, David J Witter, Karin Otte, Paul Tempest, Judith C Fleming

Bioorg Med Chem Lett· August 2007

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Male infertility and thiamine-dependent erythroid hypoplasia in mice lacking thiamine transporter Slc19a2.
Judith C Fleming, Elena Tartaglini, Ryosuke Kawatsuji, David Yao, Yuko Fujiwara, Mark D Fleming

Mol Genet Metab· November 2004

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Defective RNA ribose synthesis in fibroblasts from patients with thiamine-responsive megaloblastic anemia (TRMA).
László G Boros, Mara P Steinkamp, Judith C Fleming, Wai-Nang Paul Lee, Marta Cascante

Blood· November 2003

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