Publications by authors named "Judith Unterlass"

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Kinetic and structural characterization of NUDT15 and NUDT18 as catalysts of isoprene pyrophosphate hydrolysis.
Emma R Scaletti, Judith E Unterlass, Ingrid Almlöf, Tobias Koolmeister, Karl S Vallin

FEBS J· October 2024

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Protein-metabolite interactomics of carbohydrate metabolism reveal regulation of lactate dehydrogenase.
Kevin G Hicks, Ahmad A Cluntun, Heidi L Schubert, Sean R Hackett, Jordan A Berg, Judith Unterlass

Science· March 2023

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Pharmacological targeting of MTHFD2 suppresses acute myeloid leukemia by inducing thymidine depletion and replication stress.
Nadilly Bonagas, Nina M S Gustafsson, Martin Henriksson, Petra Marttila, Robert Gustafsson, Judith E Unterlass

Nat Cancer· February 2022

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Targeting OGG1 arrests cancer cell proliferation by inducing replication stress.
Torkild Visnes, Carlos Benítez-Buelga, Armando Cázares-Körner, Kumar Sanjiv, Bishoy M F Hanna, Judith Edda Unterlass

Nucleic Acids Res· December 2020

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Crystal structures of human PAICS reveal substrate and product binding of an emerging cancer target.
Jana Škerlová, Judith Unterlass, Mona Göttmann, Petra Marttila, Evert Homan

J Biol Chem· August 2020

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Structure-Activity Relationships (SARs) of α-Ketothioamides as Inhibitors of Phosphoglycerate Dehydrogenase (PHGDH).
Quentin Spillier, Séverine Ravez, Judith Unterlass, Cyril Corbet, Charline Degavre

Pharmaceuticals (Basel)· January 2020

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Warburg and Krebs and related effects in cancer.
Judith E Unterlass, Nicola J Curtin

Expert Rev Mol Med· September 2019

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A synthetic diphosphoinositol phosphate analogue of inositol trisphosphate.
Andrew M Riley, Judith Unterlass, Vera Konieczny, Colin W Taylor, Thomas Helleday

Medchemcomm· July 2018

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Validating and enabling phosphoglycerate dehydrogenase (PHGDH) as a target for fragment-based drug discovery in PHGDH-amplified breast cancer.
Judith E Unterlass, Arnaud Baslé, Timothy J Blackburn, Julie Tucker, Céline Cano

Oncotarget· March 2018

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A comprehensive structural, biochemical and biological profiling of the human NUDIX hydrolase family.
Jordi Carreras-Puigvert, Marinka Zitnik, Ann-Sofie Jemth, Megan Carter, Judith E Unterlass

Nat Commun· November 2017

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Structural insights into the enzymatic activity and potential substrate promiscuity of human 3-phosphoglycerate dehydrogenase (PHGDH).
Judith E Unterlass, Robert J Wood, Arnaud Baslé, Julie Tucker, Céline Cano

Oncotarget· November 2017

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